RUY ENRIQUE PEREZ MONTFORT



DATOS GENERALES
Nombre completo   RUY ENRIQUE PEREZ MONTFORT
Máximo nivel de estudios   DOCTORADO
Antigüedad académica en la UNAM   48 años
NOMBRAMIENTOS
Vigente   INVESTIGADOR TITULAR C TC Definitivo
Instituto de Fisiología Celular
Desde 01-01-2008 (fecha inicial de registros en el SIIA)
PROFESOR ASIGNATURA A TP Definitivo
Coordinación de Estudios de Posgrado
Desde 01-01-2008 (fecha inicial de registros en el SIIA)
ESTIMULOS, PROGRAMAS, PREMIOS Y RECONOCIMIENTOS
* SNI III - 2024
* PRIDE D - 2024

INFORMACIÓN DE PUBLICACIONES
Firmas  
Perez Montfort R. Pérez-Montfort R. Perez-Montfort, R Perez-Montfort, R. Perez-Montfort, Ruy
ID's SCOPUS  
55993696500 7004155242 24299267300
ORCID's  
0000-0003-0810-1159
Áreas de conocimiento  
Biochemistry & molecular biology Biochemistry and molecular biology Biology Biophysics Biotechnology & applied microbiology
Cell biology Crystallography Chemistry, medicinal Chemistry, multidisciplinary Chemistry, organic
Entomology Genetics & heredity Jcs 2008 Microbiology Multidisciplinary sciences
Obstetrics & gynecology Oncology Parasitology Scie jcr Tropical medicine
Agricultural and biological sciences (miscellaneous) Agronomy and Crop Science Biochemistry Biochemistry, Genetics and Molecular Biology (miscellaneous) Biophysics
Biotechnology Cell biology Condensed Matter Physics Chemistry (miscellaneous) Drug Discovery
Infectious Diseases Insect Science Medicine (miscellaneous) Molecular biology Multidisciplinary
Pharmaceutical science Pharmacology, Toxicology and Pharmaceutics (miscellaneous) Toxicology Veterinary (miscellaneous)
Coautorías con entidades de la UNAM  
  • Instituto de Biología
  • Instituto de Investigaciones Biomédicas
  • Instituto de Química
  • Instituto de Fisiología Celular
  • Instituto de Biotecnología
  • Facultad de Ciencias
  • Facultad de Medicina
  • Facultad de Química
  • Facultad de Estudios Superiores "Cuautitlán"
  • Escuela Nacional Preparatoria Plantel 1 "Gabino Barreda"
  • Escuela Nacional Colegio de Ciencias y Humanidades "Naucalpan"
  • Coordinación de Estudios de Posgrado
Revistas en las que ha publicado  (57):
  1. ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS, Estados Unidos America (2008)
  2. ACTA PROTOZOOLOGICA, Polonia (1994)
  3. ANALYTICAL BIOCHEMISTRY, Estados Unidos America (1989)
  4. ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, Estados Unidos America (1988)
  5. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, Estados Unidos America (1994, 2002, 2006)
  6. Archives Of Medical Research, México (1992, 1996)
  7. Archivos De Investigación Médica, México (1986)
  8. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Estados Unidos America (2002, 2018)
  9. BIOCHEMICAL JOURNAL, Reino Unido (1998)
  10. BIOCHEMISTRY, Estados Unidos America (1983, 1985, 1999, 2001, 2002, 2003, 2004, 2006, 2008)
  11. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, Países Bajos (2018)
  12. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY, (1990, 1998)
  13. BIOMEDICINE & PHARMACOTHERAPY, Francia (1995)
  14. Biotechnology Reports, Países Bajos (2017)
  15. BRAIN BEHAVIOR AND IMMUNITY, Estados Unidos America (1996)
  16. BULLETIN OF THE WORLD HEALTH ORGANIZATION, Suiza (1979)
  17. CURRENT PROTEIN & PEPTIDE SCIENCE, (2019)
  18. CURRENT TOPICS IN MEDICINAL CHEMISTRY, (2002)
  19. CHEMICO-BIOLOGICAL INTERACTIONS, Irlanda (2016)
  20. CHEMISTRY & BIOLOGY, Estados Unidos America (1995)
  21. Chemmedchem, Alemania (2016)
  22. EUROPEAN JOURNAL OF BIOCHEMISTRY, (1996, 1997, 1998)
  23. EUROPEAN JOURNAL OF CANCER, Reino Unido (1998)
  24. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, Francia (2010, 2015)
  25. EXPERIMENTAL PARASITOLOGY, Estados Unidos America (1988, 1996, 2000)
  26. Federation Proceedings, (1984)
  27. FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, Suiza (2021)
  28. FUTURE MEDICINAL CHEMISTRY, Reino Unido (2021)
  29. GACETA MEDICA DE MEXICO, México (1996)
  30. Gene, Países Bajos (1994)
  31. GYNECOLOGIC ONCOLOGY, Estados Unidos America (2005)
  32. INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY, Reino Unido (2011)
  33. JOURNAL OF BIOLOGICAL CHEMISTRY, Estados Unidos America (2004, 2005, 2008)
  34. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, Reino Unido (2013, 2014, 2023)
  35. JOURNAL OF MOLECULAR BIOLOGY, Estados Unidos America (1998, 2004)
  36. JOURNAL OF PARASITOLOGY, Estados Unidos America (1997)
  37. Journal Of The Mexican Chemical Society, México (2019)
  38. MOLECULAR AND BIOCHEMICAL PARASITOLOGY, Países Bajos (1987, 1989)
  39. MOLECULAR AND CELLULAR BIOCHEMISTRY, Países Bajos (1991)
  40. MOLECULAR BIOLOGY OF THE CELL, Estados Unidos America (2019)
  41. MOLECULAR IMMUNOLOGY, Reino Unido (1982, 1984)
  42. Molecules, Suiza (2015, 2017, 2022)
  43. NEUROBIOLOGY OF LEARNING AND MEMORY, Estados Unidos America (1995)
  44. OPEN BIOLOGY, Reino Unido (2016)
  45. PARASITOL RES, (1991, 1994, 1999)
  46. PARASITOLOGY RESEARCH, Estados Unidos America (2002, 2008, 2009)
  47. PLOS NEGLECTED TROPICAL DISEASES, Estados Unidos America (2007)
  48. PLOS ONE, Estados Unidos America (2007, 2011, 2015, 2018)
  49. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Estados Unidos America (1999)
  50. PROTEIN AND PEPTIDE LETTERS, (1997, 2011)
  51. PROTEIN EXPRESSION AND PURIFICATION, Estados Unidos America (1997)
  52. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, Estados Unidos America (2002, 2004, 2007, 2008, 2014, 2017)
  53. SCIENTIFIC REPORTS, Reino Unido (2020)
  54. Southwestern Entomologist, Estados Unidos America (2016)
  55. STRUCTURE, Estados Unidos America (2017)
  56. TROPICAL MEDICINE & INTERNATIONAL HEALTH, Estados Unidos America (1999)
  57. Veterinary Sciences, Suiza (2018)


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Documentos indexados (WoS y Scopus)

# Título del documento Autores Año Revista Fuente Citas WoS Citas Scopus
1Repurposing of rabeprazole as an anti-Trypanosoma cruzi drug that targets cellular triosephosphate isomeraseCoautor: Perez-Montfort, Ruy, Garcia-Torres, Itzhel, De la Mora-De la Mora, Ignacio, Lopez-Velazquez, Gabriel, et al.2023JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRYWoS-id: 001019362600001
Scopus-id: 2-s2.0-85163955636
22
2Phenotypic and Target-Directed Screening Yields New Acaricidal Alternatives for the Control of TicksCoautor: Pérez-Montfort R., Saporiti T., Cabrera M., Bentancur J., et al.2022MoleculesWoS-id: 000904530400001
Scopus-id: 2-s2.0-85144563968
11
3Pyrazol(in)e derivatives of curcumin analogs as a new class of anti-Trypanosoma cruzi agentsCoautor: Perez-Montfort, Ruy, Matiadis, Dimitris, Saporiti, Tatiana, Aguilera, Elena, et al.2021FUTURE MEDICINAL CHEMISTRYWoS-id: 000625283800001
Scopus-id: 2-s2.0-85103761809
66
4Protein Serine/Threonine Phosphatase Type 2C of Leishmania mexicanaCoautor: Perez-Montfort, Ruy, Escalona-Montano, Alma Reyna, Zuñiga-Fabián M., Cabrera, Nallely, et al.2021FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGYWoS-id: 000645274200001
Scopus-id: 2-s2.0-85104945901
44
5Native aggregation is a common feature among triosephosphate isomerases of different speciesCoautor: Perez-Montfort, Ruy, Rodriguez-Bolanos, Monica, Miranda-Astudillo, Hector, Perez-Castaneda, Edgar, et al.2020SCIENTIFIC REPORTSWoS-id: 000562863200001
Scopus-id: 2-s2.0-85078461387
88
6Medical and Veterinary Importance of the Moonlighting Functions of Triosephosphate Isomerase2ᵒ autor y autor de correspondencia: Perez-Montfort, Ruy, Rodríguez-Bolaños M.2019CURRENT PROTEIN & PEPTIDE SCIENCEWoS-id: 000458731200001
Scopus-id: 2-s2.0-85062078455
1717
7Key within-membrane residues and precursor dosage impact the allotopic expression of yeast subunit II of cytochrome c oxidaseCoautor: Perez-Montfort, Ruy, Rubalcava-Gracia, Diana, Garcia-Rincon, Juan, Hamel, Patrice Paul, et al.2019MOLECULAR BIOLOGY OF THE CELLWoS-id: 000481574400002
Scopus-id: 2-s2.0-85071355018
66
8Co-localization of the Receptor for Advanced Glycation End Products (RAGE) with S100 Calcium-Binding Protein B (S100B) in Human Umbilical Vein EndothelialCoautor: Perez-Montfort, R., Serratos, I. N., Lopez-Macay, A., Castellanos, P., et al.2019Journal Of The Mexican Chemical SocietyWoS-id: 000496748200003
Scopus-id: 2-s2.0-85116656976
00
9Three unrelated and unexpected amino acids determine the susceptibility of the interface cysteine to a sulfhydryl reagent in the triosephosphate isomerases of two trypanosomesCoautor y autor de correspondencia: Perez-Montfort R., Díaz-Mazariegos S., Cabrera N.2018PLOS ONEWoS-id: 000422653800008
Scopus-id: 2-s2.0-85040732112
11
10Differential effects on enzyme stability and kinetic parameters of mutants related to human triosephosphate isomerase deficiencyCoautor: Perez-Montfort, Ruy, Cabrera, Nallely, Torres-Larios, Alfredo, Garcia-Torres, Itzhel, et al.2018BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTSWoS-id: 000435048700013
Scopus-id: 2-s2.0-85044439938
1213
11A strategy based on thermal flexibility to design triosephosphate isomerase proteins with increased or decreased kinetic stabilityCoautor: Perez-Montfort, Ruy, Quezada, Andrea G., Cabrera, Nallely, Pineiro, Angel, et al.2018BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONSWoS-id: 000444791600123
Scopus-id: 2-s2.0-85051719824
33
12Novel and selective Rhipicephalus microplus triosephosphate isomerase inhibitors with acaricidal activityCoautor: Perez-Montfort, Ruy, Saramago, Luiz, Gomes, Helga, Aguilera, Elena, et al.2018Veterinary SciencesWoS-id: 000565909500014
Scopus-id: 2-s2.0-85053625419
1317
13Interplay between Protein Thermal Flexibility and Kinetic StabilityCoautor: Pérez-Montfort, R., Quezada, A.G., Díaz-Salazar, A.J., Cabrera, N., et al.2017STRUCTUREWoS-id: 000396701400016
Scopus-id: 2-s2.0-85008154386
2830
14The effect of specific proline residues on the kinetic stability of the triosephosphate isomerases of two trypanosomesCoautor: Pérez-Montfort, R., Guzmán-Luna, V., Quezada, A.G., Díaz-Salazar, A.J., et al.2017PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICSWoS-id: 000397798700002
Scopus-id: 2-s2.0-85011655872
55
15A guide to the effects of a large portion of the residues of triosephosphate isomerase on catalysis, stability, druggability, and human diseaseCoautor: Perez-Montfort, Ruy, Olivares-Illana, Vanesa, Riveros-Rosas, Hector, Cabrera, Nallely, et al.2017PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICSWoS-id: 000403700700002
Scopus-id: 2-s2.0-85018354804
2928
16Multi-Anti-Parasitic Activity of Arylidene Ketones and Thiazolidene Hydrazines against Trypanosoma cruzi and Leishmania spp.Coautor: Perez-Montfort, Ruy, Alvarez, Guzman, Perdomo, Cintya, Coronel, Cathia, et al.2017MoleculesWoS-id: 000404522900032
Scopus-id: 2-s2.0-85020167841
2225
17The importance of arginine codons AGA and AGG for the expression in E. coli of triosephosphate isomerase from seven different speciesCoautor: Perez-Montfort, R., Aguirre-López, B., Cabrera, N., de Gómez-Puyou, M.T., et al.2017Biotechnology ReportsScopus-id: 2-s2.0-85010209443
04
18Early expression of the receptor for advanced glycation end products in a toxic model produced by 6-hydroxydopamine in the rat striatumCoautor: Perez-Montfort, Ruy, Serratos, Iris N., Castellanos, Pilar, Pastor, Nina, et al.2016CHEMICO-BIOLOGICAL INTERACTIONSWoS-id: 000372404800002
Scopus-id: 2-s2.0-84959089717
78
19Potent and Selective Inhibitors of Trypanosoma cruzi Triosephosphate Isomerase with Concomitant Inhibition of Cruzipain: Inhibition of Parasite Growth through Multitarget ActivityCoautor: Pérez-Montfort R., Aguilera E., Varela J., Birriel E., et al.2016ChemmedchemWoS-id: 000380024300016
Scopus-id: 2-s2.0-84976469757
3924
20Identification of the critical residues responsible for differential reactivation of the triosephosphate isomerases of two trypanosomesCoautor y autor de correspondencia: Perez-Montfort, Ruy, Rodriguez-Bolanos, Monica, Cabrera, Nallely2016OPEN BIOLOGYWoS-id: 000385433600003
Scopus-id: 2-s2.0-84991628685
76
21Back Cover: Potent and Selective Inhibitors of Trypanosoma cruzi Triosephosphate Isomerase with Concomitant Inhibition of Cruzipain: Inhibition of Parasite Growth through Multitarget Activity (ChemMedChem 12/2016)Coautor: Pérez-Montfort, R., Aguilera, E., Varela, J., Birriel, E., et al.2016ChemmedchemScopus-id: 2-s2.0-84976513671
016
22First record of bartonella vinsonii in the sucking louse hoplopleura hirsuta1 collected from hispid cotton rats, sigmodon hispidus, in MexicoCoautor: Perez-Montfort, Ruy, Sanchez-Montes, Sokani, Guzman-Cornejo, Carmen, Herrera-Montalvo, Gerardo, et al.2016Southwestern EntomologistWoS-id: 000388733700013
Scopus-id: 2-s2.0-84996630454
25
23Modeling the interaction between quinolinate and the receptor for advanced glycation end products (RAGE): Relevance for early neuropathological processesCoautor: Pérez-Montfort R., Serratos I.N., Castellanos P., Pastor N., et al.2015PLOS ONEWoS-id: 000351275700062
Scopus-id: 2-s2.0-84924371085
1417
24Development of bis-thiazoles as inhibitors of triosephosphate isomerase from Trypanosoma cruzi. Identification of new non-mutagenic agents that are active in vivoCoautor: Pérez-Montfort R., Álvarez G., Martínez J., Varela J., et al.2015EUROPEAN JOURNAL OF MEDICINAL CHEMISTRYWoS-id: 000358097200024
Scopus-id: 2-s2.0-84935860989
3536
253-H-[1,2]Dithiole as a new anti-trypanosoma cruzi chemotype: Biological and mechanism of action studiesCoautor: Pérez-Montfort R., Couto M., Sánchez C., Dávila B., et al.2015MoleculesWoS-id: 000361375400066
Scopus-id: 2-s2.0-84941243748
1216
26Different contribution of conserved amino acids to the global properties of triosephosphate isomerasesCoautor: Pérez-Montfort R., Aguirre Y., Cabrera N., Aguirre B., et al.2014PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICSWoS-id: 000331065400013
Scopus-id: 2-s2.0-84892675123
1316
27New chemotypes as Trypanosoma cruzi triosephosphate isomerase inhibitors: A deeper insight into the mechanism of inhibitionCoautor: Pérez-Montfort R., Alvarez G., Martínez J., Aguirre-López B., et al.2014JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRYWoS-id: 000332865600007
Scopus-id: 2-s2.0-84896349759
2224
281,2,4-thiadiazol-5(4H)-ones: A new class of selective inhibitors of Trypanosoma cruzi triosephosphate isomerase. Study of the mechanism of inhibitionCoautor: Pérez-Montfort R., Alvarez G., Aguirre-López B., Cabrera N., et al.2013JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRYWoS-id: 000324402600013
Scopus-id: 2-s2.0-84874589088
1515
29Identification of Amino Acids that Account for Long-Range Interactions in Two Triosephosphate Isomerases from Pathogenic TrypanosomesCoautor: Perez-Montfort, R, Garcia-Torres, I, Cabrera, N, Torres-Larios, A, et al.2011PLOS ONEWoS-id: 000289620100018
Scopus-id: 2-s2.0-79955147061
1514
30Structural and biochemical characterization of a recombinant triosephosphate isomerase from Rhipicephalus (Boophilus) microplusCoautor: Perez-Montfort R., Moraes J., Arreola R., Cabrera N., et al.2011INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGYWoS-id: 000290355300007
Scopus-id: 2-s2.0-79954417290
1516
31A Ribosomal Misincorporation of Lys for Arg in Human Triosephosphate Isomerase Expressed in Escherichia coli Gives Rise to Two Protein PopulationsCoautor: Pérez-Montfort R., Aguirre B., Costas M., Cabrera N., et al.2011PLOS ONEWoS-id: 000292142800009
Scopus-id: 2-s2.0-79959595380
1317
32Thermodynamic and Kinetic Destabilization of Triosephosphate Isomerase Resulting from the Mutation of Conserved and Non-conserved CysteinesCoautor: Pérez-Montfort R., Cruces-Ángeles M.E., Cabrera N., Reyes-López C.A., et al.2011PROTEIN AND PEPTIDE LETTERSWoS-id: 000298540100015
Scopus-id: 2-s2.0-80054878255
55
33Massive screening yields novel and selective Trypanosoma cruzi triosephosphate isomerase dimer-interface-irreversible inhibitors with anti-trypanosomal activityCoautor: Pérez-Montfort R., Álvarez G., Aguirre-López B., Varela J., et al.2010EUROPEAN JOURNAL OF MEDICINAL CHEMISTRYWoS-id: 000285485000027
Scopus-id: 2-s2.0-78649328166
4146
34PCR for identification of species causing American cutaneous leishmaniasisCoautor: Pérez-Montfort R., Berzunza-Cruz M., Bricaire G., Suazo, N, et al.2009PARASITOLOGY RESEARCHWoS-id: 000262701400026
Scopus-id: 2-s2.0-63849123097
2423
35A monoclonal antibody that inhibits Trypanosoma cruzi growth in vitro and its reaction with intracellular triosephosphate isomeraseCoautor: Pérez-Montfort R., Cortés-Figueroa A.A., Pérez-Torres A., Salaiza N., et al.2008PARASITOLOGY RESEARCHWoS-id: 000253522900010
Scopus-id: 2-s2.0-39749186619
2122
36Key residues of loop 3 in the interaction with the interface residue at position 14 in triosephosphate isomerase from Trypanosoma bruceiCoautor: Perez-Montfort R., Cabrera N., Hernández-Alcántara G., Mendoza-Hernández G., et al.2008BIOCHEMISTRYWoS-id: 000253926500021
Scopus-id: 2-s2.0-40849092636
1212
37The conserved salt bridge linking two C-terminal beta/alpha units in homodimeric triosephosphate isomerase determines the folding rate of the monomerCoautor: Pérez-Montfort R., Reyes-López C.A., González-Mondragón E., Benítez-Cardoza C.G., et al.2008PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICSWoS-id: 000257689600015
Scopus-id: 2-s2.0-47349116319
911
38Expression, purification and preliminary X-ray diffraction studies of the transcriptional factor PyrR from Bacillus haloduransCoautor: Pérez-Montfort R., Arreola R., Vega-Miranda A., Gómez-Puyou A., et al.2008ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONSWoS-id: 000258071000004
Scopus-id: 2-s2.0-49249119652
00
39Structural basis of human triosephosphate isomerase deficiency: Mutation E104D is related to alterations of a conserved water network at the dimer interfaceCoautor: Pérez-Montfort R., Rodríguez-Almazán C., Arreola R., Rodríguez-Larrea D., et al.2008JOURNAL OF BIOLOGICAL CHEMISTRYWoS-id: 000258455400058
Scopus-id: 2-s2.0-53149132027
7374
40The Stability and Formation of Native Proteins from Unfolded Monomers Is Increased through Interactions with Unrelated ProteinsCoautor: Pérez-Montfort R., Rodríguez-Almazán C., Torner F.J., Costas M., et al.2007PLOS ONEWoS-id: 000207451500007
Scopus-id: 2-s2.0-52649135840
1011
41Crosstalk between the subunits of the homodimeric enzyme triosephosphate isomeraseCoautor: Pérez-Montfort R., Zomosa-Signoret V., Aguirre-López B., Hernández-Alcántara G., et al.2007PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICSWoS-id: 000244509700008
Scopus-id: 2-s2.0-33847338021
99
42Perturbation of the dimer interface of triosephosphate isomerase and its effect on Trypanosoma cruziCoautor: Pérez-Montfort R., Olivares-Illana V., Rodríguez-Romero A., Becker I., et al.2007PLOS NEGLECTED TROPICAL DISEASESWoS-id: 000261707200001
Scopus-id: 2-s2.0-47749092414
4847
43Loosely packed papain prosegment displays inhibitory activityCoautor: Pérez-Montfort R., Gutiérrez-González L.H., Rojo-Domínguez A., Cabrera-González N.E., et al.2006ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICSWoS-id: 000235782700006
Scopus-id: 2-s2.0-32544458651
1213
44Structural differences in triosephosphate isomerase from different species and discovery of a multitrypanosomatid inhibitor2ᵒ autor: Pérez-Montfort R., Olivares-Illana V., López-Calahorra F., Costas M., et al.2006BIOCHEMISTRYWoS-id: 000235792300011
Scopus-id: 2-s2.0-33644535470
4953
45Immunosuppressive activity of proteases in cervical carcinomaCoautor: Perez-Montfort R., Daneri-Navarro A., Del Toro-Arreola S., Sanchez-Hernandez P.E., et al.2005GYNECOLOGIC ONCOLOGYWoS-id: 000230284200018
Scopus-id: 2-s2.0-20444468420
1212
46Pyruvate kinase revisited: The activating effect of K+Coautor: Pérez-Montfort R., Oria-Hernández J., Cabrera N., Ramírez-Silva L.2005JOURNAL OF BIOLOGICAL CHEMISTRYWoS-id: 000233044500074
Scopus-id: 2-s2.0-27844607375
4848
47Conserved Cysteine 126 in Triosephosphate Isomerase Is Required Not for Enzymatic Activity but for Proper Folding and StabilityCoautor: Pérez-Montfort R., González-Mondragón E., Zubillaga R.A., Saavedra E., et al.2004BIOCHEMISTRYWoS-id: 000220276700027
Scopus-id: 2-s2.0-12144288174
5959
48An unusual triosephosphate isomerase from the early divergent eukaryote Giardia lambliaCoautor: Pérez-Montfort R., López-Velázquez G., Molina-Ortiz D., Cabrera N., et al.2004PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICSWoS-id: 000221802000005
Scopus-id: 2-s2.0-16744364095
2224
49Inactivation of triosephosphate isomerase from Trypanosoma cruzi by an agent that perturbs its dimer interfaceCoautor: Pérez-Montfort R., Téllez-Valencia A., Olivares-Illana V., Hernández-Santoyo A., et al.2004JOURNAL OF MOLECULAR BIOLOGYWoS-id: 000223480000017
Scopus-id: 2-s2.0-4143068388
6364
50Kinetic mechanism and metabolic role of pyruvate phosphate dikinase from Entamoeba histolyticaCoautor: Perez-Montfort R., Varela-Gómez M., Moreno-Sánchez R., Pardo J.P.2004JOURNAL OF BIOLOGICAL CHEMISTRYWoS-id: 000225793600031
Scopus-id: 2-s2.0-11144232331
2222
51Control of the reactivation kinetics of homodimeric triosephosphate isomerase from unfolded monomersCoautor: Pérez-Montfort R., Zomosa-Signoret V., Hernández-Alcántara G., Reyes-Vivas H., et al.2003BIOCHEMISTRYWoS-id: 000181714300018
Scopus-id: 2-s2.0-0037465762
4544
52Unfolding of triosephosphate isomerase from Trypanosoma brucei: Identification of intermediates and insight into the denaturation pathway using tryptophan mutantsCoautor: Pérez-Montfort R., Chánez-Cárdenas M.E., Fernández-Velasco D.A., Vázquez-Contreras E., et al.2002ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICSWoS-id: 000174586500001
Scopus-id: 2-s2.0-0037088535
4142
53Catalysis and stability of triosephosphate isomerase from Trypanosoma brucei with different residues at position 14 of the dimer interface. Characterization of a catalytically competent monomeric enzymeCoautor: Pérez-Montfort R., Hernández-Alcántara G., Garza-Ramos G., Hernández G.M., et al.2002BIOCHEMISTRYWoS-id: 000174792300007
Scopus-id: 2-s2.0-0037006981
2422
54Susceptibility to proteolysis of triosephosphate isomerase from two pathogenic parasites: Characterization of an enzyme with an intact and a nicked monomerCoautor: Pérez-Montfort R., Reyes-Vivas H., Martínez-Martínez E., Mendoza-Hernández G., et al.2002PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICSWoS-id: 000177068000013
Scopus-id: 2-s2.0-0037103071
2928
55Highly specific inactivation of triosephosphate isomerase from Trypanosoma cruziCoautor: Pérez-Montfort R., Téllez-Valencia A., Ávila-Ríos S., Rodríguez-Romero A., et al.2002BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONSWoS-id: 000177262000031
Scopus-id: 2-s2.0-0036377325
6161
56Polymorphism analysis of the internal transcribed spacer and small subunit of ribosomal RNA genes of Leishmania mexicanaCoautor: Pérez-Montfort R., Berzunza-Cruz M., Cabrera N., Crippa-Rossi M., et al.2002PARASITOLOGY RESEARCHWoS-id: 000178419600008
Scopus-id: 2-s2.0-0036042283
3747
57The interfaces of oligomeric proteins as targets for drug design against enzymes from parasites.1ᵉʳ autor: Perez-Montfort R., Gomez-Puyou M.T., Gomez-Puyou A.2002CURRENT TOPICS IN MEDICINAL CHEMISTRYScopus-id: 2-s2.0-0036582008
016
58Factors that control the reactivity of the interface cysteine of triosephosphate isomerase from Trypanosoma brucei and Trypanosoma cruziCoautor: Pérez-Montfort R., Reyes-Vivas H., Hernádez-Alcantara G., López-Velazquez G., et al.2001BIOCHEMISTRYWoS-id: 000167407000015
Scopus-id: 2-s2.0-0035852995
2627
59Leishmania mexicana mexicana: Genetic heterogeneity of Mexican isolates revealed by restriction length polymorphism analysis of kinetoplast DNACoautor: Pérez-Montfort R., Berzunza-Cruz M., Bricaire G., Romero S.Zuluoaga, et al.2000EXPERIMENTAL PARASITOLOGYWoS-id: 000089694900006
Scopus-id: 2-s2.0-0033820209
1516
60The efficacy of pentamidine combined with allopurinol and immunotherapy for the treatment of patients with diffuse cutaneous leishmaniasisCoautor: Perez-Montfort R., Becker I., Volkow P., Velasco-Castrejon O., et al.1999PARASITOL RESWoS-id: 000078275200001
Scopus-id: 2-s2.0-0032960092
2932
61Derivatization of the interface cysteine of triosephosphate isomerase from Trypanosoma brucei and Trypanosoma cruzi as probe of the interrelationship between the catalytic sites and the dimer interface1ᵉʳ autor: Pérez-Montfort R., Garza-Ramos G., Hernández Alcántara G., Reyes-Vivas H., et al.1999BIOCHEMISTRYWoS-id: 000079510800032
Scopus-id: 2-s2.0-0040315151
3537
62Crystal structure of triosephosphate isomerase from Trypanosoma cruzi in hexaneCoautor: Pérez-Montfort R., Gao X.-G., Maldonado E., Garza-Ramos G., et al.1999PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICAWoS-id: 000082424100026
Scopus-id: 2-s2.0-0033621083
3434
63Treatment of two patients with diffuse cutaneous leishmaniasis caused by Leishmania mexicana modifies the immunohistological profile but not the disease outcomeCoautor: Pérez-Montfort R., Salaiza-Suazo N., Volkow P., Pérez Tamayo R., et al.1999TROPICAL MEDICINE & INTERNATIONAL HEALTHWoS-id: 000084856100003
Scopus-id: 2-s2.0-0033452407
3642
64Expression and characterization of recombinant pyruvate phosphate dikinase from Entamoeba histolyticaCoautor y autor de correspondencia: Perez-Montfort R., Saavedra-Lira E., Ramirez-Silva L.1998BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGYWoS-id: 000072159400008
Scopus-id: 2-s2.0-0031888152
3137
65Urokinase-type plasminogen activator and plasminogen activator inhibitors (PAI-1 and PAI-2) in extracts of invasive cervical carcinoma and precursor lesionsCoautor: Perez-Montfort R., Daneri-Navarro A., Macias-Lopez G., Oceguera-Villanueva A., et al.1998EUROPEAN JOURNAL OF CANCERWoS-id: 000073132200028
Scopus-id: 2-s2.0-0032033452
3537
66Reactivation of triosephosphate isomerase from three trypanosomatids and human: Effect of SuraminCoautor: Perez-Montfort R., Gao X.-G., Garza-Ramos G., Saavedra-Lira E., et al.1998BIOCHEMICAL JOURNALWoS-id: 000073881900012
Scopus-id: 2-s2.0-0032524567
1110
67Differences in the intersubunit contacts in triosephosphate isomerase from two closely related pathogenic trypanosomesCoautor: Perez-Montfort R., Maldonado E., Soriano-García M., Moreno A., et al.1998JOURNAL OF MOLECULAR BIOLOGYWoS-id: 000076450900016
Scopus-id: 2-s2.0-0032538281
6163
68Sulfhydryl reagent susceptibility in proteins with high sequence similarity: Triosephosphate isomerase from Trypanosoma brucei, Trypanosoma cruzi and Leishmania mexicanaCoautor: Pérez-Montfort R., Garza-Ramos G., Cabrera N., Saavedra-Lira E., et al.1998EUROPEAN JOURNAL OF BIOCHEMISTRYScopus-id: 2-s2.0-0032079362
3547
69Crystallization and preliminary X-ray analysis of triosephosphateisomerase from Trypanosoma cruziCoautor: Pérez-Montfort R., Maldonado E., Moreno A., Panneerselvam K., et al.1997PROTEIN AND PEPTIDE LETTERSScopus-id: 2-s2.0-0005697529
07
70A mechanism of acquired resistance to complement-mediated lysis by Entamoeba histolyticaCoautor y autor de correspondencia: Pérez-Montfort R., Gutiérrez-Kobeh L., Cabrera N.1997JOURNAL OF PARASITOLOGYWoS-id: A1997WT43600011
Scopus-id: 2-s2.0-0030973762
1110
71Cloning, expression, purification and characterization of triosephosphate isomerase from Trypanosoma cruziCoautor: Pérez-Montfort R., Ostoa-Saloma P., Garza-Ramos G., Ramírez J., et al.1997EUROPEAN JOURNAL OF BIOCHEMISTRYWoS-id: A1997WP33100003
Scopus-id: 2-s2.0-0030997077
5152
72Purification of alcohol dehydrogenase from Entamoeba histolytica and Saccharomyces cerevisiae using zinc-affinity chromatographyCoautor: Pérez-Montfort R., Cabrera N., Rangel P., Hernández-Muñoz R.1997PROTEIN EXPRESSION AND PURIFICATIONWoS-id: A1997XQ12700007
Scopus-id: 2-s2.0-0031214614
66
73Energy production in Entamoeba histolytica: New perspectives in rational drug design2ᵒ autor y autor de correspondencia: Perez-Montfort R., Saavedra-Lira E.1996Archives Of Medical ResearchWoS-id: A1996VF99600001
Scopus-id: 2-s2.0-0029815186
2525
74Species-specific inhibition of homologous enzymes by modification of nonconserved amino acids residues. The cysteine residues of triosephosphate isomerase2ᵒ autor: Pérez-Montfort R., Garza-Ramos G., Rojo-Domínguez A., De Gómez-Puyou M.T., et al.1996EUROPEAN JOURNAL OF BIOCHEMISTRYWoS-id: A1996VL74800016
Scopus-id: 2-s2.0-0029836936
3438
75Insular cortex lesions impair the acquisition of conditioned immunosuppressionCoautor: Pérez-Montfort R., Ramírez-Amaya V., Alvarez-Borda B., Ormsby C.E., et al.1996BRAIN BEHAVIOR AND IMMUNITYWoS-id: A1996VF83600003
Scopus-id: 2-s2.0-0030174573
3543
76Impacto de nuevas metodologías en el estudio de parásitos.Coautor: Pérez-Montfort R., Ortega-Pierres G., Alagón A., Cortés A., et al.1996GACETA MEDICA DE MEXICOScopus-id: 2-s2.0-0030226347
00
77Entamoeba histolytica: Localization of a 30-kDa cysteine proteinase using a monoclonal antibody2ᵒ autor: Pérez-Montfort R., Becker I., Pérez-Torres A., Rondán-Zárate A., et al.1996EXPERIMENTAL PARASITOLOGYWoS-id: A1996UJ13500011
Scopus-id: 2-s2.0-0343182981
1314
78Proteolytic activity in extracts of invasive cervical carcinoma and precursor lesionsCoautor: Perez-Montfort R., Daneri-Navarro A., Del Toro-Arreola S., Bravo-Cuellar A., et al.1995BIOMEDICINE & PHARMACOTHERAPYWoS-id: A1995RW74500007
Scopus-id: 2-s2.0-0029115403
1213
79Enhancement of antibody production by a learning paradigmCoautor: Perez-Montfort R., Alvarez-Borda B., Ramirez-Amaya V., Bermudez-Rattoni F.1995NEUROBIOLOGY OF LEARNING AND MEMORYScopus-id: 2-s2.0-0029115406
2838
80Using evolutionary changes to achieve species-specific inhibition of enzyme action - studies with triosephosphate isomeraseCoautor: Perez-Montfort R., Gómez-Puyou A., Saavedra-Lira E., Becker I., et al.1995CHEMISTRY & BIOLOGYWoS-id: A1995TP78200009
Scopus-id: 2-s2.0-0029557025
7073
81Differential inactivation of rabbit and yeast triosephosphate isomerase: Effect of oxidations produced by chloramine-T2ᵒ autor: Pérez-Montfort R., Zubillaga R.A., Gómez-Puyou A.1994ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICSWoS-id: A1994PE54100019
Scopus-id: 2-s2.0-0028022857
77
82Purification and immunologic characterization of a 30-kDa cysteine proteinase of Entamoeba histolyticaCoautor: Pérez-Montfort R., Montfort L., Pérez-Tamayo R., González Canto A., et al.1994PARASITOL RESWoS-id: A1994PM66500011
Scopus-id: 2-s2.0-0028127032
109
83Proteolytic activity in extracts of Entamoeba invadens and E.histolytica: A comparative study1ᵉʳ autor: Perez-Montfort R., Engelmayer J., Ostoa-Saloma P., Gutierrez-Kobeh L., et al.1994ACTA PROTOZOOLOGICAScopus-id: 2-s2.0-0028321226
01
84Cloning and sequence determination of the gene coding for the pyruvate phosphate dikinase of Entamoeba histolytica2ᵒ autor y autor de correspondencia: Pérez-Montfort R., Saavedra-Lira E.1994GeneWoS-id: A1994NP20100014
Scopus-id: 2-s2.0-0028358231
1413
85Partial nucleotide sequence of the enzyme pyruvate, orthophosphate dikinase of Entamoeba histolytica HM1:IMSSCoautor y autor de correspondencia: Perez Montfort R., Saavedra Lira E., Robinson O.1992Archives Of Medical ResearchWoS-id: A1992BX10Y00011
Scopus-id: 2-s2.0-0027105155
43
86Altered coupling states between calcium transport and (Ca2+, Mg2+)-ATPase in the AS-30D Ascites hepatocarcinoma plasma membrane2ᵒ autor: Pérez-Montfort R., Mas-Oliva J., Cárdenas-García M., Rivas-Duro M.1991MOLECULAR AND CELLULAR BIOCHEMISTRYWoS-id: A1991EW47300005
Scopus-id: 2-s2.0-0026011355
66
87Role of leukocytes and amebic proteinases in experimental rat testicular necrosis produced by Entamoeba histolyticaCoautor: Pérez-Montfort R., Pérez-Tamayo R., Becker I., Montfort I., et al.1991PARASITOL RESWoS-id: A1991FD87100002
Scopus-id: 2-s2.0-0026031932
1210
88Causes of the decrease in fluorescence due to proteolysis of a-caseinCoautor y autor de correspondencia: Perez-Montfort R., Ostoa-Saloma P., Ramirez J.1990BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGYWoS-id: A1990EL06000009
Scopus-id: 2-s2.0-0025133328
79
89Measurement of casein digestion by a fluorometric methodCoautor y autor de correspondencia: Perez-Montfort R., Ostoa-Saloma P., Ramírez J.1989ANALYTICAL BIOCHEMISTRYWoS-id: A1989T387800007
Scopus-id: 2-s2.0-0024618472
1011
90Proteinases of Entamoeba histolytica associated with different subcellular fractionsCoautor: Perez-Montfort R., Ostoa-Saloma P., Cabrera N., Becker I.1989MOLECULAR AND BIOCHEMICAL PARASITOLOGYWoS-id: A1989R721500004
Scopus-id: 2-s2.0-0024203186
2418
91Entamoeba histolytica: Role of amebic proteinases and polymorphonuclear leukocytes in acute experimental amebiasis in the ratCoautor: Pérez-Montfort R., Becker I., Pérez-Tamayo R., Montfort I., et al.1988EXPERIMENTAL PARASITOLOGYWoS-id: A1988R259300015
Scopus-id: 2-s2.0-0024204762
3022
92Vasoactive intestinal peptide. A possible REM sleep factorCoautor: PÉREZ-MONTFORT R., DRUCKER-COLÍN R., PROSPÉRO-GARCÍA O., PACHECO M.T.1988ANNALS OF THE NEW YORK ACADEMY OF SCIENCESScopus-id: 2-s2.0-0023689261
08
93Catalytic classes of proteinases of Entamoeba histolytica1ᵉʳ autor: Perez-Montfort R., Ostoa-Saloma P., Velazquez-Medina L., Montfort I., et al.1987MOLECULAR AND BIOCHEMICAL PARASITOLOGYWoS-id: A1987K657100011
Scopus-id: 2-s2.0-0023444106
4744
94Effect of cellular immunity on the interaction between the peritoneal cell and the ameba in vitro [Efecto de la inmunidad celular en la interaccioón entre célula peritoneal y amiba in vitro.]Coautor y autor de correspondencia: Pérez-Montfort R., Pérez-Tamayo R., Martínez-Villegas J.E.1986Archivos De Investigación MédicaScopus-id: 2-s2.0-0022856465
05
95Noncovalently and covalently bound lipid on the receptor for immunoglobulin ECoautor: Perez-Montfort R., Kinet J.-P., Quarto R., Metzger H.1985BIOCHEMISTRYWoS-id: A1985AWF5000048
Scopus-id: 2-s2.0-0022396578
4032
96Hydrophobic properties of the beta and gamma subunits of the receptor for IGE1ᵉʳ autor: Perez-Montfort R., Alcaraz G., Metzger H.1984Federation ProceedingsScopus-id: 2-s2.0-0021264860
00
97Analysis of the structure and function of the receptor for immunoglobulin ECoautor: Perez-Montfort R., Metzger H., Rivnay B., Henkart M., et al.1984MOLECULAR IMMUNOLOGYWoS-id: A1984TZ39600006
Scopus-id: 2-s2.0-0021711461
2521
98Changes in the receptor for immunoglobulin E coincident with receptor-mediated stimulation of basophilic leukemia cells1ᵉʳ autor: Perez-Montfort R., Fewtrell C., Metzger H.1983BIOCHEMISTRYWoS-id: A1983RU62000009
Scopus-id: 2-s2.0-0021038483
2921
99A previously unrecognized subunit of the receptor for immunoglobulin E1ᵉʳ autor: Perez-Montfort R., Kinet J.-P., Metzger H.1983BIOCHEMISTRYWoS-id: A1983RU62000007
Scopus-id: 2-s2.0-0021096467
8160
100Covalent cross-linking of subunits of the receptor for immunoglobulin E induced by immunoprecipitation2ᵒ autor: Perez-Montfort R., Kinet J.-P., Metzger H.1983BIOCHEMISTRYWoS-id: A1983RU62000008
Scopus-id: 2-s2.0-0021096478
2012
101Proteolysis of soluble Ige-receptor complexes: Localization of sites on IgE which interact with the Fc receptor1ᵉʳ autor: Perez-Montfort R., Metzger H.1982MOLECULAR IMMUNOLOGYWoS-id: A1982PH78000005
Scopus-id: 2-s2.0-0019964251
6049
102The immunology of human and animal cysticercosis: A review2ᵒ autor: Perez-Montfort R., Flisser A., Larralde C.1979BULLETIN OF THE WORLD HEALTH ORGANIZATIONWoS-id: A1979JB93300023
Scopus-id: 2-s2.0-0018591994
8260
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Proyectos

# Nombre Participantes Convocatoria Fecha Inicio Fecha Fin
1Una nueva estrategia para el desarrollo de fármacos antitripanosomáticos.RUY ENRIQUE PEREZ MONTFORT,
Presupuesto de la UNAM asignado a la Dependencia01-01-200831-12-2028
2Enzima de Protozoarios parásitos.RUY ENRIQUE PEREZ MONTFORT,
Presupuesto de la UNAM asignado a la Dependencia01-01-201015-01-2028
3Estudios en enfermedades humanas de la triosafosfato isomerasaRUY ENRIQUE PEREZ MONTFORT,
Recursos CONACYT18-07-201615-02-2020
4Homodímeros y heterodímeros de mutantes en las argininas 98 y 99 en triosafosfato isomerasa humanaRUY ENRIQUE PEREZ MONTFORT,
Recursos PAPIIT01-01-201731-12-2018
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Docencia Impartida

# Entidad Nivel Asignatura Año Semestre Alumnos
1Facultad de CienciasMaestríaTRABAJO DE INVESTIGACIÓN III20192020-11
2Facultad de CienciasMaestríaTRABAJO DE INVESTIGACIÓN II20192019-21
3Facultad de CienciasMaestríaTRABAJO DE INVESTIGACIÓN I20182019-11
4Facultad de QuímicaMaestríaTRABAJO DE INVESTIGACION III20172018-11
5Facultad de QuímicaMaestríaTRABAJO DE INVESTIGACIÓN II20172017-21
6Facultad de QuímicaMaestríaSEMINARIO DE INVESTIGACION III20162016-21
7Facultad de QuímicaMaestríaTRABAJO DE INVESTIGACION III20162016-21
8Facultad de QuímicaMaestríaSEMINARIO DE INVESTIGACION II20152016-11
9Facultad de QuímicaMaestríaTRABAJO DE INVESTIGACION II20152016-11
10Facultad de QuímicaMaestríaTRABAJO DE INVESTIGACION I20152015-21
11Facultad de QuímicaMaestríaSEMINARIO DE INVESTIGACION I20152015-21
12Facultad de QuímicaMaestríaCURSO I20142014-227
13Facultad de QuímicaMaestríaTRABAJO DE INVESTIGACION III20142014-21
14Facultad de QuímicaMaestríaTRABAJO DE INVESTIGACION II20132014-11
15Facultad de QuímicaMaestríaTRABAJO DE INVESTIGACION III20122012-21
16Facultad de QuímicaMaestríaSEMINARIO DE INVESTIGACION III20122012-21
17Facultad de QuímicaMaestríaSEMINARIO DE INVESTIGACION II20112012-11
18Facultad de QuímicaMaestríaSEMINARIO DE INVESTIGACION III20112012-11
19Facultad de QuímicaMaestríaTRABAJO DE INVESTIGACION III20112012-11
20Facultad de QuímicaMaestríaTRABAJO DE INVESTIGACION II20112012-11
21Facultad de QuímicaMaestríaTRABAJO DE INVESTIGACION I20112011-21
22Facultad de QuímicaMaestríaTRABAJO DE INVESTIGACION III20112011-21
23Facultad de QuímicaMaestríaTRABAJO DE INVESTIGACION II20112011-21
24Facultad de QuímicaMaestríaSEMINARIO DE INVESTIGACION I20112011-21
25Facultad de QuímicaMaestríaSEMINARIO DE INVESTIGACION II20112011-21
26Facultad de QuímicaMaestríaSEMINARIO DE INVESTIGACION I20102011-11
27Facultad de QuímicaMaestríaTRABAJO DE INVESTIGACION I20102011-11
28Facultad de QuímicaMaestríaTRABAJO DE INVESTIGACION II20102011-11
29Facultad de QuímicaMaestríaTRABAJO DE INVESTIGACION III20102011-11
30Facultad de QuímicaMaestríaTRABAJO DE INVESTIGACION III20102010-21
31Facultad de QuímicaMaestríaTRABAJO DE INVESTIGACION II20102010-21
32Facultad de QuímicaMaestríaTRABAJO DE INVESTIGACION II20092010-11
33Facultad de MedicinaLicenciaturaTRABAJO DE INVESTIGACION 420092009-21
34Facultad de MedicinaLicenciaturaTRABAJO DE INVESTIGACION 320082009-11
35Facultad de QuímicaMaestríaSEMINARIO DE INVESTIGACION IV20072008-11
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Capítulos de libros (Humanindex)

# Título del libro Título del capítulo ISBN Editorial Año Fuente