| 1 | The -514C>T polymorphism in the LIPC gene modifies type 2 diabetes risk through modulation of HDL-cholesterol levels in Mexicans | Coautor: Rodríguez-Guillen R., Guerra-García M.T., Moreno-Macías H., Ochoa-Guzmán A., et al. | 2021 | JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION | WoS-id: 000545040800001
Scopus-id: 2-s2.0-85087490959
| 10 | 10 |
| 2 | Familial hypertriglyceridemia: an entity with distinguishable features from other causes of hypertriglyceridemia | Coautor: Rodriguez-Guillen, Rosario, Cruz-Bautista, Ivette, Huerta-Chagoya, Alicia, Moreno-Macias, Hortensia, et al. | 2021 | LIPIDS IN HEALTH AND DISEASE | WoS-id: 000620219200002
Scopus-id: 2-s2.0-85101485953
| 7 | 8 |
| 3 | Spasmogenic and spasmolytic activities of Agastache mexicana ssp mexicana and A. mexicana ssp xolocotziana methanolic extracts on the guinea pig ileum | 2ᵒ autor: Rodriguez, Rodolfo, Ventura-Martinez, Rosa, Eva Gonzalez-Trujano, Maria, Angeles-Lopez, Guadalupe E., et al. | 2017 | JOURNAL OF ETHNOPHARMACOLOGY | WoS-id: 000393529900007
Scopus-id: 2-s2.0-85006833509
| 15 | 16 |
| 4 | Novel colon cancer susceptibility variants identified from a genome-wide association study in African Americans | Coautor: Rodríguez-Guillén, R., Wang, H., Schmit, S.L., Haiman, C.A., et al. | 2017 | INTERNATIONAL JOURNAL OF CANCER | WoS-id: 000400158800012
Scopus-id: 2-s2.0-85017121986
| 21 | 21 |
| 5 | Measuring the Effectiveness of Pharmacology Teaching in Undergraduate Medical Students | Coautor y autor de correspondencia: Rodriguez, R, Urrutia-Aguilar, ME, Martinez-Gonzalez, A | 2012 | JOURNAL OF PATIENT SAFETY | WoS-id: 000313585500005
Scopus-id: 2-s2.0-84857924566
| 2 | 7 |
| 6 | Acute morphological changes in guinea-pig ileum myenteric neurons after ischemia in situ with superfusion in vitro | Coautor: Rodriguez, R, Ventura-Martinez, R, Santiago-Mejia, J, Gomez, C, et al. | 2008 | PATHOLOGY RESEARCH AND PRACTICE | WoS-id: 000254172400006
Scopus-id: 2-s2.0-38949122359
| 8 | 10 |
| 7 | Bilateral sequential common carotid artery sectioning in mice as a new model for testing neuroprotective drugs | 1ᵉʳ autor: Rodriguez R., Rodriguez-Boscan I., Lugo-Sira D., Vidrio H., et al. | 2000 | J STROKE CEREBROVASC | Scopus-id: 2-s2.0-0033759975
| 0 | 11 |
| 8 | Changing the countenance of pharmacology courses: Disappearance of live biology, and the cultivation of depersonalized clinical language [2] (multiple letters) | 2ᵒ autor: Rodriguez R., Thron C.D., Vidrio H., Lopez-Martinez E., et al. | 1998 | TRENDS IN PHARMACOLOGICAL SCIENCES | WoS-id: 000072089400006
Scopus-id: 2-s2.0-0031904906
| 0 | 0 |
| 9 | Changing the countenance of pharmacology courses in medical schools | 1ᵉʳ autor: Rodriguez R., Vidrio H., Lopez-Martinez E., Contreras E., et al. | 1997 | TRENDS IN PHARMACOLOGICAL SCIENCES | Scopus-id: 2-s2.0-0030776773
| 0 | 7 |
| 10 | Influence of chronic prenatal and postnatal administration of naltrexone in locomotor activity induced by morphine in mice | Coautor: Rodriguez R., Jimenez M.M., Estrada M.L., Medina M. | 1997 | Archives Of Medical Research | WoS-id: A1997WN84300011
Scopus-id: 2-s2.0-0030901899
| 8 | 10 |
| 11 | Anticholinergic properties of progesterone in the isolated ileum of the guinea-pig | 1ᵉʳ autor: Rodríguez R., Fernandez G., Ramírez R., Medina M. | 1996 | DRUG DEVELOPMENT RESEARCH | WoS-id: A1996VF05000006
Scopus-id: 2-s2.0-0029760013
| 2 | 3 |
| 12 | Involvement of nitric oxide in bone marrow-derived natural suppressor activity: Its dependence on IFN-? | 2ᵒ autor: Rodriguez R., Angulo I., Garcia B., Medina M., et al. | 1995 | JOURNAL OF IMMUNOLOGY | WoS-id: A1995RE57400004
Scopus-id: 2-s2.0-0029065835
| 66 | 77 |
| 13 | Comparative efficacy and safety of intravenous non-steroidal anti-inflammatory drugs in two animal models of pain | 1ᵉʳ autor: Rodriguez R., Medina M., Rojas Y. | 1995 | DRUG DEVELOPMENT RESEARCH | WoS-id: A1995TL85000006
Scopus-id: 2-s2.0-0029557657
| 1 | 0 |
| 14 | Mitotic index and cell proliferation kinetics for identification of antineoplastic activity | Coautor: Rodriguez R., Rojas E., Herrera L.A., Sordo M., et al. | 1993 | ANTI-CANCER DRUGS | WoS-id: A1993MP02900005
Scopus-id: 2-s2.0-0027761916
| 92 | 99 |
| 15 | Experimental models of epilepsy [Modelos experimentales de epilepsia.] | Coautor: Rodríguez R., Fernández Guardiola A., Tapia R., Brailowsky S., et al. | 1992 | GACETA MEDICA DE MEXICO | Scopus-id: 2-s2.0-0026893718
| 0 | 4 |
| 16 | Are mitotic index and lymphocyte proliferation kinetics reproducible endpoints in genetic toxicology testing? | Coautor: Rodriguez R., Rojas E., Montero R., Herrera L.A., et al. | 1992 | Mutation Research Letters | WoS-id: A1992JH19400009
Scopus-id: 2-s2.0-0026751696
| 41 | 43 |
| 17 | Effect of various psychotropic drugs on the performance of avoidance and escape behaviors in rats | 1ᵉʳ autor y autor de correspondencia: Rodriguez R. | 1992 | PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR | WoS-id: A1992JZ94300027
Scopus-id: 2-s2.0-0026448321
| 17 | 17 |
| 18 | Opioid like effects of cycloheximide and bacitracin | Coautor: Rodriguez R., Figueroa-Hernandez J.L., Garcia E., Medina M. | 1991 | Proceedings of the Western Pharmacology Society | Scopus-id: 2-s2.0-0025815064
| 0 | 0 |
| 19 | Pertussis toxin increases sensitivity to the lethal effect of morphine in mice | Coautor: Rodriguez R., Campos-Sepulveda A.E., Garcia-Sainz J.A., Lujan M. | 1991 | Proceedings of the Western Pharmacology Society | Scopus-id: 2-s2.0-0025899581
| 0 | 0 |
| 20 | Effects of anticonvulsants on intestinal kindling | 1ᵉʳ autor: Rodriguez R., Ramirez R., Lujan M., Medina M., et al. | 1991 | Proceedings of the Western Pharmacology Society | Scopus-id: 2-s2.0-0025885380
| 0 | 0 |
| 21 | Neonatal monosodium glutamate reduced pentobarbital hypnotic susceptibility in adult mice | Coautor: Rodriguez R., Gomez C., Lujan M., Servin D., et al. | 1991 | Proceedings of the Western Pharmacology Society | Scopus-id: 2-s2.0-0025894853
| 0 | 0 |
| 22 | GABA withdrawal signs in the isolated guinea pig ileum | Coautor y autor de correspondencia: Rodriguez R., Ramirez R., Lujan M. | 1991 | Proceedings of the Western Pharmacology Society | Scopus-id: 2-s2.0-0025740298
| 0 | 0 |
| 23 | Acute toxicity of casiopeine, a new type of cytotoxic agent | Coautor: Rodriguez R., Garcia E., Medina M., Rojas Y., et al. | 1991 | Proceedings of the Western Pharmacology Society | Scopus-id: 2-s2.0-0025812667
| 0 | 2 |
| 24 | Electrocardiographic alterations induced by repeated electrical stimulation of the heart at low intensity | Coautor: Rodríguez R., García-Márquez F., Moreno J.A., Luján M. | 1988 | LIFE SCIENCES | WoS-id: A1988M655600003
Scopus-id: 2-s2.0-0023921252
| 0 | 0 |
| 25 | Relaxant action of androgens, progestins and corticosteroids on the isolated ileum of the guinea pig. | Coautor: Rodríguez R., Kubli-Garfias C., Medina-Jiménez M., García-Yañez E., et al. | 1987 | Acta Physiologica Et Pharmacologica Latinoamericana : Organo De La Asociacion Latinoamericana De Ciencias Fisiolo | WoS-id: A1987J853000005
Scopus-id: 2-s2.0-0023488592
| 18 | 19 |
| 26 | Kindling-like convulsive activities in the isolated ileum of the guinea pig. I. Electrical stimulation | 2ᵒ autor: Rodríguez R., Luján M., Capistrán C., Velasco F., et al. | 1987 | EXPERIMENTAL NEUROLOGY | WoS-id: A1987K720600005
Scopus-id: 2-s2.0-0023640618
| 1 | 2 |
| 27 | Kindling-like phenomenon in the isolated ileum of the guinea-pig | 1ᵉʳ autor: Rodríguez R., Capistrán C.M., López E., Beltrán del Río L., et al. | 1986 | LIFE SCIENCES | WoS-id: A1986D782200002
Scopus-id: 2-s2.0-0022529789
| 2 | 2 |
| 28 | Quantitative and temporal characteristics of photocell measured locomotor activity in a sample of mice | Coautor: Rodriguez R., Izazola Conde C., Garcia E., Mata Moreno E. | 1983 | Proceedings of the Western Pharmacology Society | WoS-id: A1983QS86700064
Scopus-id: 2-s2.0-0020656334
| 0 | 0 |
| 29 | Effects of different parameters of stimulation on the naloxone induced contraction in the electrically stimulated guinea-pig ileum | Coautor y autor de correspondencia: RODRIGUEZ R., Mosqueda R., Lujan M. | 1982 | Federation Proceedings | Scopus-id: 2-s2.0-17944387974
| 0 | 0 |
| 30 | Involvement of neuronal components in the contractile response of electrically stimulated ileum to naloxone | Coautor: RODRIGUEZ R., Lujan M., Lopez E., Aguilar H. | 1982 | Federation Proceedings | Scopus-id: 2-s2.0-19244378687
| 0 | 0 |
| 31 | Pharmacological characterization of opiate physical dependence in the isolated ileum of the guinea-pig | 2ᵒ autor y autor de correspondencia: RODRIGUEZ R., Lujan M. | 1981 | BRITISH JOURNAL OF PHARMACOLOGY | WoS-id: A1981MA75900009
Scopus-id: 2-s2.0-0019408030
| 49 | 46 |
| 32 | Pharmacological characterization of the contraction induced by naloxone in the isolated guinea-pig ileum stimulated at high frequencies [CARACTERIZACION FARMACOLOGICA DE LA CONTRACION INDUCIDA POR LA NALOXONA EN EL ILEO AISLADO DE COBAYO EST | Coautor y autor de correspondencia: Rodriguez R., Valencia-Flores I.G., Lujan M. | 1981 | Boletín De Estudios Médicos Y Biológicos | Scopus-id: 2-s2.0-0019844602
| 0 | 0 |
| 33 | Analgesia brought about by electric stimulation in the mouse. Effect of naloxone. Preliminary results [ANALGESIA PRODUCIDA POR ESTIMULACION ELECTRICA EN EL RATON. EFECTO DE LA NALOXONA. RESULTADOS PRELIMINARES] | Coautor y autor de correspondencia: Rodriguez R., Campos A.E., Lujan M. | 1981 | Boletín De Estudios Médicos Y Biológicos | Scopus-id: 2-s2.0-0019856212
| 0 | 0 |
| 34 | Electrically induced narcotic-like dependence in the isolated guinea-pig ileum | Coautor y autor de correspondencia: Rodríguez R., Luján M., Valencia-Flores G. | 1980 | LIFE SCIENCES | WoS-id: A1980KN55200010
Scopus-id: 2-s2.0-0019123538
| 9 | 6 |
| 35 | Toward a behavioral toxicology of paint thinner | Coautor y autor de correspondencia: Rodriguez R., Colotla V.A., Lorenzana-Jimenez M. | 1980 | Neurobehavioral Toxicology And Teratology | WoS-id: A1980JW08000006
Scopus-id: 2-s2.0-0019164465
| 9 | 6 |
| 36 | Use of the isolated guinea-pig ileum for experimental analysis of physical drug-dependence [EL USO DEL ILEO AISLADO DE COBAYO EN EL ANALISIS EXPERIMENTAL DE LA DEPENDENCIA FISICA A NARCOTICOS] | 1ᵉʳ autor: Rodriguez R., Lujan M. | 1980 | Boletín De Estudios Médicos Y Biológicos | Scopus-id: 2-s2.0-0019239668
| 0 | 0 |
| 37 | Effects of solvents on schedule-controlled behavior | Coautor: Rodriguez R., Colotla V.A., Bautista S., Lorenzana-Jimenez M. | 1979 | Neurobehavioral Toxicology And Teratology | Scopus-id: 2-s2.0-0018685887
| 0 | 38 |
| 38 | Role of prostaglandin E2 in the manifestation of morphine dependence in the isolated guinea-pig ileum [PARTICIPACION DE PROSTAGLANDINA E2 EN LA MANIFESTACION DE LA DEPENDENCIA A MORFINA EN EL ILEO AISLADO DE COBAYO] | Coautor: Rodriguez R., Valencia-Flores G., Aguilar H., Lujan M. | 1979 | Boletín De Estudios Médicos Y Biológicos | Scopus-id: 2-s2.0-0018552547
| 0 | 0 |
| 39 | Increased sensitivity to naloxone of animals pretreated with p-chlorophenylalanine: Temporal variation of this phenomenon [AUMENTO EN LA SENSIBILIDAD A LA NALOXONA EN ANIMALES PRETRATADOS CON p-CLOROFENILALANINA. LA VARIACION TEMPORAL DE EST | Coautor: Rodriguez R., Campos A.E., Medina M., Lujan M. | 1979 | Boletín De Estudios Médicos Y Biológicos | Scopus-id: 2-s2.0-0018553237
| 0 | 0 |
| 40 | Effect of naloxone on the stretch response induced with acetylcholine in the mouse [EFECTO DE LA NALOXONA SOBRE LA RESPUESTA DE ESTIRAMIENTO INDUCIDA POR LA ACETILCOLINA EN EL RATON] | Coautor: Rodriguez R., Garcia E., Medina M., Lujan M. | 1979 | Boletín De Estudios Médicos Y Biológicos | Scopus-id: 2-s2.0-0018553467
| 0 | 0 |
| 41 | Effect of a long-term rhythm on the susceptibility of the guinea-pig ileum to naloxone [EVIDENCIA DE UN RITMO DE LARGA DURACION EN LA SUSCEPTIBILIDAD DEL ILEO DE COBAYO A LA NALOXONA] | 2ᵒ autor y autor de correspondencia: Rodriguez R., Lujan M. | 1979 | Boletín De Estudios Médicos Y Biológicos | Scopus-id: 2-s2.0-0018617148
| 0 | 0 |
| 42 | Effect of naloxone on locomotor activity of mice intoxicated with morphine [EFECTO DE LA NALOXONA SOBRE LA ACTIVIDAD LOCOMOTORA DEL RATON INTOXICADO CON MORFINA] | Coautor: Rodriguez R., Figueroa-Hernandez J.L., Medina M., Lujan M. | 1979 | Boletín De Estudios Médicos Y Biológicos | Scopus-id: 2-s2.0-0018623949
| 0 | 0 |
| 43 | d-Amphetamine effects on behavior produced by periodic food deliveries in the rat | Coautor y autor de correspondencia: Rodriguez R., Nieto J., Makhlouf C. | 1979 | PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR | WoS-id: A1979HT82100010
Scopus-id: 2-s2.0-0018635878
| 8 | 9 |
| 44 | Morphine dependence in the isolated guinea-pig ileum and its modification by p-chlorophenylalanine | 1ᵉʳ autor: Rodríguez R., Luján M., Campos A.E., Chorné R. | 1978 | LIFE SCIENCES | WoS-id: A1978FP77800006
Scopus-id: 2-s2.0-0018260551
| 12 | 13 |
| 45 | Further characterization of opiate physical dependence in the isolated guinea-pig ileum | 2ᵒ autor y autor de correspondencia: Rodriguez R., Lujan M. | 1978 | Pharmacologist | Scopus-id: 2-s2.0-0018096327
| 0 | 4 |
| 46 | The effect of p-chlorophenylalanine pretreatment of the phenomena of acute tolerance and dependence to morphine in the isolated guinea pig ileum | Coautor: Rodriguez R., Lujan M., Izazola-Conde C., Valencia-Flores G. | 1977 | Federation Proceedings | Scopus-id: 2-s2.0-0017414953
| 0 | 0 |
| 47 | Preliminary evidence indicating that tolerance and physical dependence on morphine are mediated by different mechanisms of action [EVIDENCIA PRELIMINAR DE QUE LA TOLERANCIA Y LA DEPENDENCIA FISICA A LA MORFINA SON MEDIADAS POR DISTINTOS MECA | Coautor: Rodriguez R., Lujan M., Izazola-Conde C., Valencia-Flores G. | 1977 | Boletín De Estudios Médicos Y Biológicos | Scopus-id: 2-s2.0-0017561696
| 0 | 0 |
| 48 | The teaching of pharmacology in the formation of the general practitioner [La enseñanza de la farmacologiá en la formación del médico general] | 1ᵉʳ autor: Rodríguez R., Alcántara G., Medina-Maldonado E. | 1976 | GACETA MEDICA DE MEXICO | Scopus-id: 2-s2.0-0016936491
| 0 | 0 |
| 49 | Serotoninergic mechanism and physical dependence of morphine [Mecanismos serotonérgicos y dependencia física a la morfina] | 1ᵉʳ autor: Rodríguez R., Luján M., Chorné R., Campos A.E. | 1976 | GACETA MEDICA DE MEXICO | Scopus-id: 2-s2.0-0016986902
| 0 | 0 |
| 50 | Participation of serotonin in physical drug dependence [PARTICIPACION DE LA SEROTONINA EN LA DEPENDENCIA FISICA A NARCOTICOS] | Coautor: Rodriguez R., Lujan M., Guerrero F., Chorne R. | 1974 | Boletín De Estudios Médicos Y Biológicos | Scopus-id: 2-s2.0-0016133972
| 0 | 0 |
| 51 | Analgesic properties of narcotic antagonists [PROPIEDADES ANALGESICAS DE LOS ANTAGONISTAS DE LOS NARCOTICOS] | 1ᵉʳ autor y autor de correspondencia: Rodriguez R. | 1974 | Archivos De Investigación Médica | WoS-id: A1974V302900012
Scopus-id: 2-s2.0-0016142676
| 1 | 1 |
| 52 | Serotoninergic mechanisms and mental depression [MECANISMOS SEROTONERGICOS Y DEPRESION MENTAL] | 1ᵉʳ autor y autor de correspondencia: Rodriguez R. | 1974 | Boletín De Estudios Médicos Y Biológicos | Scopus-id: 2-s2.0-0016223707
| 0 | 0 |
| 53 | Serotonin-like actions of quipazine on the central nervous system | 1ᵉʳ autor: Rodríguez R., Rojas-Ramírez J.A., Drucker-Colín R.R. | 1973 | EUROPEAN JOURNAL OF PHARMACOLOGY | WoS-id: A1973R476400007
Scopus-id: 2-s2.0-0015692053
| 155 | 124 |
| 54 | Reversal by narcotics and narcotic antagonists of pain-induced functional impairment. | 1ᵉʳ autor: Rodríguez R., Pardo E.G. | 1973 | Advances In Biochemical Psychopharmacology | Scopus-id: 2-s2.0-0015832616
| 0 | 2 |
| 55 | Bicyclic Mannich bases. 1. Psychotropic activity of 2-(4-aryl-1-piperazinyl)bicyclo[3.3.1]nonan-9-ones and derivatives | Coautor y autor de correspondencia: RODRIGUEZ R., Schut R.N., Ward F.E. | 1972 | JOURNAL OF MEDICINAL CHEMISTRY | WoS-id: A1972L758200022
Scopus-id: 2-s2.0-0015305993
| 9 | 7 |
| 56 | Antagonism of tremorine-induced tremor by serotoninergic agents in mice. Interactions with levodopa. | 1ᵉʳ autor y autor de correspondencia: Rodríguez R. | 1972 | LIFE SCIENCES | WoS-id: A1972M476200004
Scopus-id: 2-s2.0-0015350535
| 23 | 14 |
| 57 | Quipazine, a new type of antidepressant agent | 1ᵉʳ autor: Rodríguez R., Pardo E.G. | 1971 | Psychopharmacology | WoS-id: A1971J946600012
Scopus-id: 2-s2.0-0014999164
| 63 | 52 |
| 58 | Experimental substantiation of the therapeutic usefulness of quipazine [VALIDACION EXPERIMENTAL DEL USO TERAPEUTICO DE LA QUIPAZINA] | 1ᵉʳ autor: Rodriguez R., Vera Trueba J., Pardo E.G., Cervantes M. | 1971 | Neurologia-Neurocirugia Psiquiatria | Scopus-id: 2-s2.0-0015162892
| 0 | 0 |
| 59 | General pharmacology of Zolertine, a new antihypertensive agents [Farmacología general de la zolertina, un nuevo agente antihipertensor.] | 2ᵒ autor: Rodríguez R., Vidrio H., Hong E., Magaña J.L., et al. | 1968 | GACETA MEDICA DE MEXICO | Scopus-id: 2-s2.0-0014329434
| 0 | 0 |
| 60 | High vacuum isolation valve | 2ᵒ autor y autor de correspondencia: Rodríguez R.G., Guerrero J.M. | 1968 | REVIEW OF SCIENTIFIC INSTRUMENTS | WoS-id: A1968B792700043
Scopus-id: 2-s2.0-36849106348
| 0 | 0 |
| 61 | New antihypertensive aminoalkyltetrazoles | Coautor: RODRIGUEZ R., Hayao S., Havera H.J., Strycker W.G., et al. | 1967 | JOURNAL OF MEDICINAL CHEMISTRY | WoS-id: A19679253700025
Scopus-id: 2-s2.0-33947338601
| 63 | 46 |
| 62 | Effect of Non-Steroidal Anti-Inflammatory Drugs in the Evans Blue Pleural Effusion | 2ᵒ autor y autor de correspondencia: Rodriguez R., Sancilio L.F. | 1966 | P SOC EXP BIOL MED | WoS-id: A19668738800020
Scopus-id: 2-s2.0-0013991420
| 12 | 6 |
| 63 | Reversal by acetylsalicylic acid of pain induced functional impairment | 2ᵒ autor y autor de correspondencia: Rodríguez R., Pardo E.G. | 1966 | LIFE SCIENCES | Scopus-id: 2-s2.0-0344319346
| 0 | 16 |
| 64 | PHARMACOLOGY OF A GROUP OF PHENYLPIPERAZINE TETRAZOLE DERIVATIVES WITH | 1ᵉʳ autor: RODRIGUEZ R., HONG E., VIDRIO H., PARDO E.G. | 1965 | JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS | WoS-id: A19656394900008
Scopus-id: 2-s2.0-78651185701
| 21 | 5 |
| 65 | SOME CONSEQUENCES OF LONG-TERM MECAMYLAMINE ADMINISTRATION TO | Coautor: RODRIGUEZ R., VIDRIO H., GOMEZ J., PARDO E.G. | 1965 | JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS | WoS-id: A19656657700014
Scopus-id: 2-s2.0-0004931403
| 4 | 2 |
| 66 | COMPARATIVE STUDY OF A GROUP OF ADRENERGIC BLOCKING AGENTS. | 1ᵉʳ autor: RODRIGUEZ R., Vidrio H., PARDO E.G. | 1964 | Boletin Del Instituto De Estudios Medicos Y Biologicos, Universidad Nacional Autonoma De Mexico | Scopus-id: 2-s2.0-78651154268
| 0 | 0 |
ID's SCOPUS 