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Título del libro: Coagulation: Kinetics, Structure Formation And Disorders
Título del capítulo: Coagulation: Kinetic, structure, formation and disorders

Autores UNAM:
ARNULFO HERNAN NAVA ZAVALA;
Autores externos:

Idioma:
Inglés
Año de publicación:
2012
Palabras clave:

Coagulation; Hemophilia; Hemostasis; Thrombophilia


Resumen:

Maintenance of normal blood flow requires equilibrium between procoagulant and anticoagulant factors it is named hemostasis, occasionally procoagulant activity predominates, leading to clots formation; frequently, tissue damage is the triggering factor. Hereditary factors, primary or acquired play a role in the development of thrombosis. Primary thrombophilia is associated to hereditary factors, which promote hypercoagulability because natural anticoagulants are not exerting their activity. On the other hand, acquired thrombophilia may occur associated to autoimmune diseases, cancer, surgical procedures, pregnancy, postpartum period, and obesity. Activation of the coagulation system is characterized by the co-participation of inflammatory response components, factors related to the subjacent disease, and other procoagulant factors. The study of hemostasis in the patients should include both inflammatory and autoimmune response markers. © 2012 by Nova Science Publishers, Inc. All rights reserved.


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