Título del libro: Benzodiazepine: Abuse And Therapeutic Uses, Pharmacology And Health Effects
Título del capítulo: Risk factors for benzodiazepine dependence in women with major depression or anxiety disorders
ANA FRESAN ORELLANA;
Autores externos:
Idioma:
Inglés
Año de publicación:
2012
Palabras clave:
Anxiety disorders; Benzodiazepine dependence; Major depression; Women
Resumen:
Benzodiazepines (BDZ) have been for many decades a focus of interest in the field of pharmacology. They are one of the most commonly prescribed medications around the world and Mexico is not the exception: as anxiolytics and hypnotics, as well as for other indications in general medicine BDZ are the most consumed drugs of prescription in general population. Despite their great level of efficacy and safety, BDZ dependence is still a common concern for many clinicians occurring even at prescribed therapeutic dose-range. Unlike dependence to other psychoactive drugs, BDZ dependence is a condition that may be found related to its therapeutic framework and starting by a medical prescription. In mental health settings, people with psychiatric disorders are particularly at a greater risk for developing BDZ dependence since these medications are commonly used for the treatment of several psychiatric syndromes and symptoms, especially those related to anxiety and insomnia, which are frequent manifestations of depression. Although BDZ dependence among psychiatric patients is mainly reported in males, due to the more elevated prevalence of depression and anxiety in females, it is conceivable that this risk must be higher in women. However BDZ dependence in women with primary major depressive or anxiety disorders is usually overlooked when it should be an area of clinical relevance for its necessity of prevention and early management. Objective: In the present study we describe the socio-demographic characteristics and forms of prescription of BDZ in women with major depression or anxiety disorders. We then compare those who developed dependence with those who did not aiming to determine which of these variables may represent risk factors for the development of dependence. In accordance to previous reports with respect to socio-demographic variables, our hypothesis was that patients with dependence will be more frequently single, older, and with a higher educational level than those without dependence. Also, we anticipated that BDZ dependence would be related to an earlier onset of use and to a longer duration of treatments. All these variables will significantly predict BDZ dependence in this population. Method: One hundred and forty one female patients were included in the study, 86 (61%) with majo
Entidades citadas de la UNAM:
ISBN:
9781620816424
Editorial:
Nova Science Publishers, Inc. Nombre de la publicación:
Risk factors for benzodiazepine dependence in women with major depression or anxiety disorders
Página inicial:
91
Página final:
10
Tipo de producto:
Capítulo de un Libro
