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Título del libro: Antimicrobial Peptides: Properties, Functions And Role In Immune Response
Título del capítulo: Antimicrobial peptides: Immunomodulatory properties, functions and therapeutic applications in humans

Autores UNAM:
LUIS MANUEL TERAN JUAREZ;
Autores externos:

Idioma:
Inglés
Año de publicación:
2013
Resumen:

Antimicrobial peptides (AMPs) are small peptides which exhibit broad-spectrum antimicrobial activity and often activity against virus. In addition AMPs exert several functions including endotoxin neutralization, chemotactic and immunomodulating activities, angiogenesis, and wound repair. In recent years, the AMPs have been implicated in several diseases including psoriasis, atopic dermatitis, rosacea, and Crohn's ileal disease among others. Because of their therapeutic effects, some of these peptides have been used successfully in the treatment of several pathologies such acne vulgaris, periodontal disease, and cancer. This chapter provides an overview of the main AMPs in humans, and discuss their properties, functions, and role in immune response. © 2013 by Nova Science Publishers, Inc. All rights reserved.


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