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Título del libro: Advanced Sensor And Detection Materials
Título del capítulo: The Role of the Shape in the Design of New Nanoparticles

Autores UNAM:
GETHZEMANI MAYELI ESTRADA VILLEGAS; EMILIO BUCIO CARRILLO;
Autores externos:

Idioma:
Inglés
Año de publicación:
2014
Palabras clave:

Controlled drug delivery; Nanoparticles; Nanorods; Particle size; Particles (particulate matter); Surface chemistry; Synthesis (chemical); Targeted drug delivery; Yarn; Drug release; Nanocarriers; Particle shape; Polymer particles; Vectorization; Polymers


Resumen:

A number of design parameters that govern the functional behavior of nanocarriers, including the choice of polymer, particle size, and surface chemistry, have been in focus to optimize their performance in vivo. The size and shape of the nanoparticle strongly affects the transport through different biological barriers and circulation times. Currently, many novel shapes of nanoparticles exist, designed with different polymeric materials such as gold nanorods, carbon nanotubes, and fullerenes; and polymeric materials with hexagonal forms, helicoidal, toroidal, conical, ellipsoid, disks and others shapes synthesized with different monomer mixes. Another example is shapes made by fiber electrospun technique (sheet, attacked sheet, folded sheet, spiral wounded sheet, tube, and thread fibers). We discuss the methods of fabrication and the viability to synthesize new nanomaterials that can improve the release of drugs, the importance of particle shape and their role as a nanocarrier. © 2014 Scrivener Publishing LLC. All rights reserved.


Entidades citadas de la UNAM: