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Título del libro: Stem Cells And Human Diseases
Título del capítulo: Cancer stem cells in solid tumors, markers and therapy

Autores UNAM:
ELIZABETH LANGLEY MCCARRON; ALEJANDRO MANUEL GARCIA CARRANCA;
Autores externos:

Idioma:
Inglés
Año de publicación:
2012
Palabras clave:

Cancer; Cancer stem cell targets; Cancer stem cell therapy; Cancer stem cells; Solid tumors


Resumen:

Cancer is a multi-factorial disease related with a high number of deaths in the world. There are three cancer models which try to explain the origin and behavior of most known cancers: The stochastic, hierarchical and phenotype plasticity models, which are not exclusive of one an other. However, the most common cancers known until now follow the hierarchical model. In this model only cancer stem cells and some early progenitor cells have the capacity to initiate tumor growth. In this chapter, we focus on the cancers that follow this hierarchical model and the current therapeutic strategies designed to eliminate cancer stem cells in order to improve patient health. © 2012 Springer Science+Business Media B.V. All rights reserved.


Entidades citadas de la UNAM: