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Título del libro: Seeds As Functional Foods And Nutraceuticals: New Frontiers In Food Science
Título del capítulo: The use of soybean protein as a functional food to control lipid metabolism in some chronic diseases

Autores UNAM:
ARMANDO ROBERTO TOVAR PALACIO;
Autores externos:

Idioma:
Inglés
Año de publicación:
2014
Resumen:

The soybean is a high-protein legume with a protein digestibility chemical aminoacid score (PDCAAS) of 1, indicating that is a high-quality protein. For this reason,during the early 70's, the consumption of soy protein in combination with other vegetableproteins were used to fight against malnutrition in developing countries. In the last twodecades, advances in molecular biology have permitted the understanding of themolecular mechanism of action of this legume. It has been demonstrated that the aminoacid composition as well as the presence of bioactive compounds such as isoflavonesplay an important role in the regulation of lipid metabolism mediated by the transcriptionfactor SREBP-1, which in turn regulate insulin secretion and insulin sensitivity. Recentstudies have demonstrated that long term consumption of soy protein plays a significantrole in the management of some chronic diseases related with obesity such aslipotoxicity, diabetes and fatty liver disease by regulating the expression of severaltranscription factors involved in fatty acid synthesis, fatty acid oxidation, cholesterolsynthesis and leptin. Now, the nutrigenomics have permitted the development oftranslational nutrition to use the discoveries in nutrition and their application to benefitboth society and the food industry. Recently, we have designed a different type of dietaryportfolio (combination of 2 or more functional foods) including soy protein for specificdiseases and to reduce biochemical abnormalities frequently observed in subjects withsome chronic diseases. © 2014 Nova Science Publishers, Inc.


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