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Título del libro: Proceedings Of The 2006 Ieee Symposium On Computational Intelligence In Bioinformatics And Computational Biology, Cibcb'06
Título del capítulo: Fuzzy C-means for inferring functional coupling of proteins from their phylogenetic profiles

Autores UNAM:
JUAN ENRIQUE MORETT SANCHEZ;
Autores externos:

Idioma:

Año de publicación:
2006
Palabras clave:

Artificial intelligence; Clustering algorithms; Fuzzy clustering; Fuzzy systems; Proteins; Cluster of orthologous groups; Functional relationship; Fuzzy C mean; Fuzzy c-means clustering algorithms; Phylogenetic profile; Bioinformatics


Resumen:

This paper explores the use of the fuzzy C-means clustering algorithm for inferring functional relationships among proteins from their phylogenetic profiles. We conducted a series of experiments using phylogenetic profiles provided by the Cluster of Orthologous Groups of Proteins (COG) database. Experimental results demonstrate that the increasing expressiveness of fuzzy C-means enables the discovery of functional relationships on E.coli operons which traditional methods fail to detect. ©2006 IEEE.


Entidades citadas de la UNAM: