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SIIA Público
SISTEMA INTEGRAL DE INFORMACIÓN ACADÉMICA - PÚBLICO
Título del libro: Proceedings Of The 10th International Joint Conference On Biomedical Engineering Systems And Technologies, Vol 1: Biodevices Título del capítulo: Analysis of Impedance Spectroscopy Measurements of Biological Tissue using the Distribution of Relaxation Times Method
Biological Tissue; Electrical Impedance Spectroscopy; Distribution of Relaxation Times Method
Resumen:
This work proposes a method for analysing electrical impedance
spectroscopy (EIS) measurements of biological tissue in the range of 100
Hz to 1 MHz by means of the distribution of relaxation times (DRT) to
evaluate and study the different relaxation time constant involved in
electrical response. We numerically analyse different configurations of
RC circuits and compare the electrical response in time domain by DRT
with that of classical EIS representation in frequency domain as Bode
plots. Experimental validation of the technique using RC circuits, gives
an error of less than 1% for the EIS measurement system with respect to
theoretical calculation. We present preliminary measurements for WISTAR
rat tissue samples of spleen, lung and kidney fixed in formaldehyde
solution at 3.8% founding a more detailed occurrence of relaxation
mechanism that could provide useful information about the structure and
composition of biological tissues in a more precise way.
