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Título del libro: Current Progress In Medical Mycology
Título del capítulo: Sporothrix and sporotrichosis

Autores UNAM:
JOSE ALEXANDRO BONIFAZ TRUJILLO;
Autores externos:

Idioma:
Inglés
Año de publicación:
2017
Palabras clave:

Amphotericin B; Cutaneous lymphatic; Itraconazole; Pulmonary; Sporothrix brasiliensis; Sporothrix schenckii; Sporotrichosis; Yeasts


Resumen:

Sporotrichosis is the mycosis due to implantation of greatest global distribution. It is caused by a complex of thermodymorphic fungi of cryptic species, of which the most frequent and important are Sporothrix schenckii and Sporothrix brasiliensis. These fungi live in nature, matter in decomposition and several plants. The route of entry usually involves traumatic inoculation, but sometimes it could be by the respiratory route. In general, they produce a condition confined to the subcutaneous cellular tissue and, to a lesser extent, affect various viscera, such as the lungs and central nervous system. Clinically, it is a polymorphic condition with various manifestations depending mainly on the patient?s immune status and strain virulence. In cases associated with immunosuppression, cutaneous and extracutaneous features may occur. The main clinical form is lymphangitic cutaneous sporotrichosis. In this chapter, the authors discuss the biological aspects of the main pathogenic species of the Sporothrix schenckii complex, including virulence factors, clinical-epidemiological aspects, diagnosis, and treatment. © Springer International Publishing AG 2017.


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