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Título del libro: 2014 Ieee 4th International Conference On Computational Advances In Bio And Medical Sciences, Iccabs 2014
Título del capítulo: Structural vs. functional mechanisms of duplicate gene loss following whole genome doubling

Autores UNAM:

Autores externos:

Idioma:
Inglés
Año de publicación:
2014
Palabras clave:

Functional mechanisms; Gene duplications; Gene loss; Genome doubling; Genes


Resumen:

The process of whole genome doubling (WGD) gives rise to two copies of each chromosome in a genome, containing the same genes in the same order. Through an attrition mechanism known as fractionation, one of each pair of duplicate genes is lost over evolutionary time, resulting in an interleaving patterns of deletions from duplicated regions [1]. This differentiates the WGD/fractionation model from general approaches to gene duplication, pioneered by El-Mabrouk [2]. © 2014 IEEE.


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