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Título del libro: Phagocytosis: Overview, History And Role In Human Health And Disease
Título del capítulo: Receptor signaling during phagocytosis

Autores UNAM:
CARLOS ROSALES LEDEZMA; EILEEN URIBE QUEROL;
Autores externos:

Idioma:
Inglés
Año de publicación:
2018
Resumen:

Phagocytosis is an elegant but complex process for the ingestion and elimination of particles larger than 5 µm in diameter, including microbial pathogens, foreign toxic substances, and apoptotic cells. Hence, phagocytosis is fundamental for tissue homeostasis. Almost all types of cells perform phagocytosis. However, a specialized group of cells called professional phagocytes can perform phagocytosis with high efficiency. Professional phagocytes include monocytes, macrophages, neutrophils, dendritic cells, osteoclasts, and eosinophils. Phagocytosis can be divided into various steps: i) recognition of the target particle, ii) signaling to activate the internalization machinery, and iii) phagosome formation. In this chapter, we present a general view of the phagocytic receptors and describe the signaling pathways involved in phagocytosis. © 2018 Nova Science Publishers, Inc. All rights reserved.


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