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Título del libro: Phagocytosis: Overview, History And Role In Human Health And Disease
Título del capítulo: The first 100 years of phagocytosis

Autores UNAM:
CARLOS ROSALES LEDEZMA;
Autores externos:

Idioma:
Inglés
Año de publicación:
2018
Resumen:

Phagocytosis is a fundamental biological process performed by cells of multiple organisms. In unicellular organisms, phagocytosis is mainly a feeding process. But in pluricellular organisms, almost all types of cells can perform phagocytosis at different levels. However, specialized cells called professional phagocytes can perform phagocytosis with high efficiency. These phagocytes ingest microbial pathogens, foreign toxic substances, and dying cells. Consequently, phagocytosis is required for tissue remodeling and defense of the organism. Yet, phagocytosis was not at first, recognized as an important part of the immune system. It was Ilya Metchnikoff (1845-1916) who described phagocytosis a little over 100 years ago. He defended it in his cellular theory against the scientists who considered that immunity was due only to humoral factors, such as antibodies. Metchnikoff is considered the father of modern cellular immunology and for this, he was awarded the Nobel Prize in 1908. He Phagocytosis is a fundamental biological process performed by cells of multiple organisms. In unicellular organisms, phagocytosis is mainly a feeding process. But in pluricellular organisms, almost all types of cells can perform phagocytosis at different levels. However, specialized cells called professional phagocytes can perform phagocytosis with high efficiency. These phagocytes ingest microbial pathogens, foreign toxic substances, and dying cells. Consequently, phagocytosis is required for tissue remodeling and defense of the organism. Yet, phagocytosis was not at first, recognized as an important part of the immune system. It was Ilya Metchnikoff (1845-1916) who described phagocytosis a little over 100 years ago. He defended it in his cellular theory against the scientists who considered that immunity was due only to humoral factors, such as antibodies. Metchnikoff is considered the father of modern cellular immunology and for this, he was awarded the Nobel Prize in 1908. © 2018 Nova Science Publishers, Inc. All rights reserved.


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