Título del libro: Nanostructured Biomaterials For Regenerative Medicine
Título del capítulo: Nanostructured biomaterials with antimicrobial activity for tissue engineering
ARGELIA ALMAGUER FLORES; PHAEDRA SURIEL SILVA BERMUDEZ;
Autores externos:
Idioma:
Año de publicación:
2019
Palabras clave:
Antimicrobials; Bacterial adhesion; Biofilms; Biomaterial-related infections; Fungal infections; Hybrid nano-materials; Nanostructured biomaterials; Surface functionalization; Surface modifications
Resumen:
Nanostructured biomaterials have gained interest for tissue engineering applications since they exhibited excellent biological and mechanical features. However, biomaterial-related infections are still a major drawback; it is a persistent problem that can cause the failure of the implant and could compromise the life of the patient. This kind of infections occurs when microbial cells colonize the biomaterial?s surface before the adhesion and growth of the desired host tissue cells. This chapter describes initially the mechanisms of microbial adhesion, growth, and biofilm formation since such knowledge is essential for developing antimicrobial strategies. These strategies include chemical or physical surface modifications, the use of nano-pattern surfaces and nanoparticles, as well as the implementation of hybrid processes to deliver antimicrobial substances. Here in, we present a summary of the latest approaches proposed to prevent, and control, microbial colonization. In addition, a brief critical discussion of the methods and associated techniques used to evaluate the antibacterial response of the different nanostructured strategies applied to biomaterials is also included. © 2020 Elsevier Ltd. All rights reserved.
Entidades citadas de la UNAM:
ISBN:
9780081025956
Editorial:
WOODHEAD PUBL LTD Nombre de la publicación:
Nanostructured biomaterials with antimicrobial activity for tissue engineering
Página inicial:
81
Página final:
137
