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Título del libro: Bio-Pigmentation And Biotechnological Implementations
Título del capítulo: Biotechnological Production of Melanins with Microorganisms

Autores UNAM:
GUILLERMO GOSSET LAGARDA;
Autores externos:

Idioma:
Inglés
Año de publicación:
2017
Palabras clave:

biotechnological process development; engineered microorganisms; melanin production; microbial production; microbial strains; molecular biology


Resumen:

This chapter discusses advances in the processes and microbial strains used in melanin production. Melanin production is dependent mainly on the activity of enzymes from the tyrosinase and laccase protein families. The capacity to produce melanins has been observed in diverse microorganisms in their natural environment. To improve melanin production, biotechnological process development, and optimization approaches have been employed. The chapter also provides examples of such approaches. Advances in molecular biology enable the genetic engineering of an ever-increasing number of microbes, generating recombinant production strains. These advances have enabled the accumulation of knowledge related to the identification and characterization of genes related to the synthesis of melanin precursors and the enzymes involved in their oxidation, thus opening the possibility of genetically engineering organisms for enhanced melanin production or transferring this trait to a nonmelanogenic microorganism. © 2017 John Wiley & Sons, Inc.


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