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SISTEMA INTEGRAL DE INFORMACIÓN ACADÉMICA - PÚBLICO
Título del libro: Aerobic Utilization Of Hydrocarbons, Oils, And Lipids Título del capítulo: Membrane Lipid Degradation and Lipid Cycles in Microbes
All living cells are delimited from the exterior world by a membrane,
and membrane-forming lipids are the structural determinants for membrane
assembly and maintenance. Although biosynthesis of membrane-forming
lipids is well understood in many organisms, turnover, degradation, and
remodeling of these lipids are less studied. An initial degradation of
glycerol-containing membrane lipids may occur by (phospho)lipases or
transferases which remove distinct groups from the membrane lipid
converting it into a lysolipid or diacylglycerol. These degradation
intermediates can either be totally degraded into
low-molecular-weight-metabolites or missing groups can be reintroduced
onto the intermediates to convert them into fully functional membrane
lipids again, thereby completing a lipid cycle. Classic examples in
Escherichia coli are the lyso-phosphatidylethanolamine cycle, the
diacylglycerol cycle, or cycles involving the isoprenoid undecaprenol.
It is evident that many more lipid cycles exist in other proteobacteria
and in grampositive bacteria and that these cycles play major roles in
decorating biomolecules located outside the cytoplasmic compartment.
Entidades citadas de la UNAM:
Fuente:
ISBN: 9783319504186 Editorial: SPRINGER INTERNATIONAL PUBLISHING AG