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Título del libro: Melanin-Concentrating Hormone And Sleep: Molecular, Functional And Clinical Aspects
Título del capítulo: Cannabinoids, sleep, and the MCH system

Autores UNAM:

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Año de publicación:
2018
Resumen:

Marijuana is a colloquial name given to Cannabis sativa, which has been used for diverse purposes, including as a therapeutical element for multiple health issues. The neurobiological effects of C. sativa involve a complex biological machinery including receptors, named CB1 and CB2 cannabinoid receptors. These receptors recognize endogenous cannabinoid-like compounds, such as anandamide and 2-arachinonolglycerol which seems to display sleep-inducing properties. Along decades, the study of the putative role of exogenous and endogenous cannabinoids in sleep modulation has brought critical data. Since endocannabinoids have been described in sleep-related brain areas, intriguing issues regarding whether hypothalamic substrates, such as MHC, may be interacting with the endocannabinoids have been raised. © Springer International Publishing AG, part of Springer Nature 2018.


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