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Título del libro: Gecco 2022 Companion - Proceedings Of The 2022 Genetic And Evolutionary Computation Conference Título del capítulo: Neuroevolution based Multi-Objective Algorithm for Gene Selection and Microarray Classification
Autores UNAM: Autores externos: Idioma: Año de publicación: 2022Palabras clave:
microarray; gene selection; neuroevolution
Resumen:
Microarrays allow the expression level analysis of thousands of genes
simultaneously; thus, it is a common technique used for cancer detection
and diagnosis. However, existing microarray datasets have huge data
dimension and class imbalance, therefore, it is important to find
relevant genes that accurately set classes apart and allow building more
reliable classification models. A multi-objective algorithm is proposed
to evolve artificial neural networks' topology and connection weights
for microarray classification by minimizing the number of selected genes
and the cross-entropy loss. The algorithm is based on the evolutionary
multi-objective algorithm SMS-EMOA along with the genetic encoding and
the crossover and mutation operators from the neuroevolution algorithms
NEAT/N3O. Moreover, a speciation algorithm was implemented to protect
the diversity of the selected features within the solutions. To test the
algorithm performance, open datasets were used, most of them were
gathered from the Curated Microarray Database (CuMiDa). The algorithm
performance was measured by the geometric mean, the number of selected
features, and the population hypervolume, and it was compared against
N3O on microarray binary classification problems with competitive
results. Furthermore, the results were investigated for statistical
significance and show that the novel algorithm has a promising
performance on the problem at hand.
Entidades citadas de la UNAM:
Fuente:
ISBN: 9781450392686 Editorial: Association for Computing Machinery, Inc