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Título del libro: The Entomological Guide To Rhipicephalus
Título del capítulo: Types of acaricide resistance

Autores UNAM:
ENRIQUE ALEJANDRO REYNAUD GARZA;
Autores externos:

Idioma:

Año de publicación:
2021
Palabras clave:

Acaricide resistance; Metabolic resistance and target-site insensitivity; Resistance mechanisms; Tick control


Resumen:

The cattle tick infestations and the bovine infectious diseases transmitted by them, are controlled mainly by the massive use of acaricides on the livestock, however, this strategy has led to the emergence of tick resistance to most acaricide formulations, and the lack of acaricide effectiveness has become a severe threat to the strategies to control of ticks and tick borne diseases, consequently, it is a necessity to monitor the spread of acaricide resistancein order to design preventive and alternative measures of tick control in endemic areas, for a long time this has been done by toxicological bioassays using living field-isolated ticks of various development stages exposed to the different acaricide formulations, these procedures are time-consuming and expensive because they require abundant specialized labor and facilities, therefore, the use of fast molecular test is required to overcome the disadvantages of outdated bioassays. The design of a molecular test requires in the first place, the identification of the molecular mechanism of acaricide resistance in the cattle tick to the different acaricide chemical formulations, acaricide resistance is a genetically inherited phenomenon that involves the expression products of one or several genes. Two major genetic-driven mechanisms are recognized nowadays, namely: a) enhanced metabolic detoxification involving an activity increase of one or several xenobiotic metabolizing enzymes, b) altered target sites involving DNA mutations of the genes that code for the proteins that are targeted by the acaricide, this chapter describes themolecular and biochemical mechanisms that cause resistance to the most common acaricides used for tick control. © 2021 Nova Science Publishers, Inc. All rights reserved.


Entidades citadas de la UNAM: