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Título del libro: Nanomaterials And Nanotechnology In Medicine
Título del capítulo: Nanopharmaceuticals

Autores UNAM:
DAVID QUINTANAR GUERRERO; GERARDO LEYVA GOMEZ;
Autores externos:

Idioma:

Año de publicación:
2022
Palabras clave:

Active pharmaceutical gradients; Advanced drug-delivery systems; Dendrimers; Liposomes; Nanopharmaceuticals; Nanotechnology; Polymer nanomedicines; Solid lipid nanoparticles; Synthetic lipids


Resumen:

One of the specific applications of nanotechnology has been in the creation of advanced drug-delivery systems, which have given rise to the term "nanopharmaceuticals". Liposomes are a submicron and vesicular system for the transport and release of drugs; they are composed of a bilayer or multiple layers of natural or synthetic lipids with a central aqueous compartment. Polymer nanomedicines are the simplest form of nanomedicines and contain soft materials to increase solubility, biocompatibility, half-life, and bioavailability, as well as to control the release of active pharmaceutical gradients from nanomedicines in the body. One of the major attractions of Solid Lipid Nanoparticles has been the issue of toxicity, attributed to lipid composition. Dendrimers are a type of versatile three-dimensional, hyperbranched nanostructure whose size, shape, and topology can be controlled precisely during the synthesis process and prepared by means of iterative methods. © 2023John Wiley & Sons Ltd. All rights reserved.


Entidades citadas de la UNAM: