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Título del libro: One Century Of The Discovery Of Arsenicosis In Latin America (1914-2014): As 2014 - Proceedings Of The 5th International Congress On Arsenic In The Environment
Título del capítulo: Some cardiovascular effects of inorganic arsenic exposure in children exposed to drinking water

Autores UNAM:
CITLALLI OSORIO YAÑEZ; GUADALUPE AGUILAR MADRID;
Autores externos:

Idioma:
Inglés
Año de publicación:
2014
Palabras clave:

Arsenic; Blood; Metabolites; Potable water; Aortic root; Cross-sectional study; Diastolic blood pressures; Exposed to; Inorganic arsenic; Left ventricular hypertrophies; Left ventricular mass; Mexican children; Blood pressure


Resumen:

The present study investigates associations of inorganic arsenic (iAs) exposure, blood pressure and structural echocardiographic parameters in a cross sectional study of 173 Mexican children residents in an endemic area who presented concentrations of total speciated arsenic (tAs) in urine ranging from 5.7 to 370 ng As/mL. Results show that children in the highest exposure percentile (75th or <678 µg As/L/year) of cumulative As exposure (SAsE) were related to increased systolic or diastolic Blood Pressure (DBP), had higher Left Ventricular Mass (LVM) and increased Aortic Root Diameter (ARD) than children in the lowest exposure percentile p25th or <307 µg As/L/year). DBP and LVM were not related to iAs metabolites, but ARD were positively associated with the methyl-As (MAs) level in urine. In conclusion, we observed increased diastolic prehypertension and increased concentric left ventricular hypertrophy prevalence in children exposed to iAs. © 2014 Taylor & Francis Group.


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