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Título del libro: Diet And Nutrition In Dementia And Cognitive Decline
Título del capítulo: Olive Oil and Huntington's Disease

Autores UNAM:

Autores externos:

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Año de publicación:
2015
Palabras clave:

Antioxidants; Huntington's disease; Mediterranean diet; Neuroprotective; Olive oil; Oxidative stress


Resumen:

The benefits of the Mediterranean diet for the general status of human health are gaining attention due to the many antioxidative properties of its several components. As a primary constituent of the Mediterranean diet, olive oil contains an important number of antioxidants, which in turn represent a first line of defense against the noxious actions of reactive species, chemical species involved in aging, and the development of neurodegenerative features in neurological disorders. One of these disorders is Huntington's disease. Evidence collected from experimental models suggests that some components of olive oil could be responsible for the reduction of oxidative stress and the stimulation of neuroprotective mechanisms in the Huntington's disease phenotype, thereby suggesting that these molecules could be considered as potential therapeutic tools against this disorder. In this review we briefly describe and discuss this evidence, highlighting its relevance for a design of therapeutic approaches. © 2015 Elsevier Inc. All rights reserved.


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