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Título del libro: Clinical Virology
Título del capítulo: Astrovirus

Autores UNAM:
CARLOS FEDERICO ARIAS ORTIZ; TOMAS DAVID LOPEZ DIAZ;
Autores externos:

Idioma:

Año de publicación:
2016
Palabras clave:

Astrovirus; Chemical treatment; Clinical manifestations; Epidemiological studies; Illness pathogenesis; Immune response; Laboratory diagnosis; Virology


Resumen:

Hepatitis E was recognized as a disease in 1980 following a large outbreak of unexplained hepatitis in Kashmir, India, in 1978. The outbreak affected 52, 000 individuals, mostly young adults, with a self-limiting hepatitis similar to hepatitis A (1). However, this was not hepatitis A, because there was a very high mortality rate in afflicted pregnant women. Further, most of those infected had previously been exposed to HAV (2). In 1983, the causative virus was discovered by electron microscopy in the stool of a scientist from the former USSR who drank a pooled fecal extract from Soviet troops with unexplained hepatitis serving in Afghanistan (3). The viral genome was sequenced and given the name HEV in 1990 (4). Many of the historical outbreaks of unexplained hepatitis in Asia and other developing areas were subsequently found in retrospect to be caused by HEV (5, 6). © 2017 by ASM Press.


Entidades citadas de la UNAM: