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Título del libro: Turkey Diseases And Disorders: Volume 1: Bacterial And Fungal Infectious Diseases
Título del capítulo: Clostridial Dermatitis in Turkeys

Autores UNAM:
XOCHITL HERNANDEZ VELASCO; DANIEL HERNANDEZ PATLAN; BRUNO SOLIS CRUZ; VICTOR MANUEL PETRONE GARCIA;
Autores externos:

Idioma:

Año de publicación:
2024
Palabras clave:

Antibiotic alternatives; C. septicum; Cellulitis; Clostridial dermatitis; Immunization; Pathogenesis


Resumen:

Clostridial dermatitis (CD) or cellulitis is a per-acute fatal clostridial disease affecting turkeys primarily as they approach market age. C. septicum is primarily associated with CD in commercial turkeys. In 2010, the US Animal Health Association ranked CD among the top 10 infectious diseases affecting turkeys. Like gangrenous dermatitis (GD) in broilers, it is expected that skin scratches in turkeys could be the main predisposing factor. However, the exact pathogenesis of CD is unknown. Two theories have been reported to describe the pathogenesis of CD: (i) the inside-out theory that suggests translocation of C. septicum from the gastrointestinal tract due to increased intestinal permeability and (ii) the outside-in theory that suggests contamination of the wounds or abrasions with C. septicum spores present in the litter. Several attempts have been made to control the diseases using vaccination. Immunization with the inactivated vaccine against C. septicum requires multiple doses, which is not economically feasible. However, vaccination with a live attenuated C. septicum vaccine followed by administration of a C. septicum bacterin toxoid oil emulsion vaccine could mitigate the incidence of dermatitis on farms that have a history of CD outbreaks. Further research is needed to understand CD?s pathogenesis and identify effective antibiotic alternatives to control dermatitis in commercial turkeys. © Springer Nature Switzerland AG 2024.


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