LEONILA IRMA LAURA ESCOBAR PEREZ



DATOS GENERALES
Nombre completo   LEONILA IRMA LAURA ESCOBAR PEREZ
Máximo nivel de estudios   DOCTORADO
Antigüedad académica en la UNAM   34 años
NOMBRAMIENTOS
Vigente   PROFESOR DE CARRERA TITULAR C TC Definitivo
Facultad de Medicina
Desde 01-04-2016
PROFESOR DE CARRERA TITULAR B TC Definitivo
Facultad de Medicina
Desde 01-01-2008 (fecha inicial de registros en el SIIA) hasta 31-03-2016
ESTIMULOS, PROGRAMAS, PREMIOS Y RECONOCIMIENTOS
* SNI II2022 - VIGENTE
* SNI II2014 - 2020
* SNI I2008
* PRIDE D2016 - 2024
* PASPA Estancias Sabáticas2014
* PASPA Estancias de Investigación en el extranjero2012
* CATEDRA BERNARDO SEPULVEDA GUTIERREZ2018
* CATEDRA BERNARDO SEPULVEDA GUTIERREZ2017
* CATEDRA BERNARDO SEPULVEDA GUTIERREZ2016

INFORMACIÓN DE PUBLICACIONES
Firmas  
Escobar L. Escobar L.I. Escobar Perez, Laura Escobar, I, Laura Escobar, L Escobar, Laura
Escobar, Laura I. Escobar, LI Escobar-Pérez L. EscobarPerez, L Escobar-Perez, Laura
ID's SCOPUS  
56013879100
ORCID's  
0000-0002-5142-8993
Áreas de conocimiento  
Biochemistry and molecular biology Biology Biophysics Cell biology Chemistry, physical
Immunology Mathematics, interdisciplinary applications Medicine, general and internal Microscopy Multidisciplinary sciences
Pharmacology & pharmacy Pharmacology and pharmacy Physiology Urology & nephrology Urology and nephrology
Agricultural and Biological Sciences (miscellaneous) Atomic and Molecular Physics, and Optics Biochemistry, genetics and molecular biology (miscellaneous) Biophysics Clinical Biochemistry
Endocrinology Genetics (clinical) Histology Immunology and allergy Medical Laboratory Technology
Medicine (miscellaneous) Nephrology Pediatrics, Perinatology and Child Health Spectroscopy Toxicology
Urology
Coautorías con entidades de la UNAM  
  • Instituto de Investigaciones Biomédicas
  • Instituto de Química
  • Instituto de Fisiología Celular
  • Instituto de Neurobiología en Querétaro, Querétaro
  • Facultad de Ciencias
  • Facultad de Filosofia y Letras
  • Facultad de Medicina
  • Facultad de Química
  • Facultad de Estudios Superiores "Iztacala"
Revistas en las que ha publicado  (34):
  1. ACTA PEDIATRICA DE MEXICO, México (2015)
  2. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, Estados Unidos America (2004)
  3. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, Estados Unidos America (2010)
  4. ANALYTICAL BIOCHEMISTRY, Estados Unidos America (1990)
  5. Archivos De Investigación Médica, México (1984)
  6. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Estados Unidos America (2020)
  7. BIOCHEMISTRY, Estados Unidos America (1993)
  8. Biochemistry International, (1992)
  9. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, Países Bajos (2001)
  10. Biochimie, Francia (1992)
  11. BOLETIN MEDICO DEL HOSPITAL INFANTIL DE MEXICO, México (2013)
  12. FASEB JOURNAL, Estados Unidos America (2010)
  13. FEBS LETTERS, Estados Unidos America (2005)
  14. FEBS OPEN BIO, Reino Unido (2021)
  15. FRONTIERS IN IMMUNOLOGY, Suiza (2022)
  16. HISTOCHEMISTRY AND CELL BIOLOGY, Estados Unidos America (2010, 2016)
  17. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, Suiza (2019)
  18. INTERNATIONAL JOURNAL OF QUANTUM CHEMISTRY, Estados Unidos America (2012)
  19. JOURNAL OF BIOLOGICAL CHEMISTRY, Estados Unidos America (1995)
  20. JOURNAL OF CHROMATOGRAPHY A, Países Bajos (1983, 1984)
  21. JOURNAL OF MOLECULAR HISTOLOGY, Países Bajos (2014, 2020)
  22. JOURNAL OF PHYSICAL CHEMISTRY B, Estados Unidos America (2003)
  23. Journal Of The Mexican Chemical Society, México (2008)
  24. KIDNEY INTERNATIONAL, Estados Unidos America (2011)
  25. LIFE SCIENCES, Reino Unido (2003)
  26. Molecular Genetics & Genomic Medicine, Estados Unidos America (2016)
  27. Nefrologia, España (2013, 2016, 2018, 2023)
  28. Neurobiology, (1998)
  29. Peptides, Estados Unidos America (2010)
  30. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, Estados Unidos America (2016)
  31. PLOS ONE, Estados Unidos America (2013)
  32. REVISTA DE INVESTIGACION CLINICA-CLINICAL AND TRANSLATIONAL INVESTIGATION, México (2012, 2014, 2015)
  33. Tetrahedron, Reino Unido (1986)
  34. Toxicon, Reino Unido (1999, 2025)


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Documentos indexados (WoS y Scopus)

# Título del documento Autores Año Revista Fuente Citas WoS Citas Scopus
1Block of Kv1 potassium channels and NMR structure of recombinant conotoxin ?-SrXIA1ᵉʳ autor: Escobar L.I., Quezada Suaste C.D., Salvador C., Aparicio D.L., et al.2025ToxiconScopus-id: 2-s2.0-105004273282
00
2Autosomal dominant distal renal tubular acidosis in two pediatric patients with mutations in the SLC4A1 gene. Can the maximum urinary pCO2 test be normal?Coautor: Escobar, LI, Hernández, NEG, Tenorio, CG, Silva, LPM, et al.2023NefrologiaWoS-id: 001115657000001
10
3Autosomal dominant distal renal tubular acidosis in two pediatric patients with mutations in the SLC4A1 gene. Can the maximum urinary pCO2 test be normal?Coautor: Escobar L.I., Guerra Hernández N.E., Gómez Tenorio C., Méndez Silva L.P., et al.2023NefrologiaScopus-id: 2-s2.0-85172453393
01
4An ambient-temperature stable nanoparticle-based vaccine for nasal application that confers long-lasting immunogenicity to carried antigensCoautor: Escobar, Laura, Cruz-Resendiz, Adolfo, Acero, Gonzalo, Sampieri, Alicia, et al.2022FRONTIERS IN IMMUNOLOGYWoS-id: 000885604000001
Scopus-id: 2-s2.0-85142040450
44
5Identification of a unique endoplasmic retention motif in the Xenopus GIRK5 channel and its contribution to oocyte maturationCoautor: Escobar, Laura I., Rangel-Garcia, Claudia I., Salvador, Carolina, Chavez-Garcia, Karla, et al.2021FEBS OPEN BIOWoS-id: 000624457100001
Scopus-id: 2-s2.0-85101883321
33
6?Funny? channels in cardiac mitochondria modulate membrane potential and oxygen consumptionCoautor: Escobar, I, Laura, Padilla-Flores, Teresa, Lopez-Gonzalez, Zinaeli, Vaca, Luis, et al.2020BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONSWoS-id: 000526795700036
Scopus-id: 2-s2.0-85079423731
1113
7Metabolic acidosis and hyperkalemia differentially regulate cation HCN3 channel in the rat nephronCoautor: Escobar, Laura I., Lopez-Gonzalez, Zinaeli, Padilla-Flores, Teresa, Leon-Aparicio, Daniel, et al.2020JOURNAL OF MOLECULAR HISTOLOGYWoS-id: 000579565100001
Scopus-id: 2-s2.0-85092604733
34
8Novel Potassium Channels in Kidney Mitochondria: The Hyperpolarization-Activated and Cyclic Nucleotide-Gated HCN ChannelsCoautor: Escobar, Laura I., Leon-Aparicio, Daniel, Salvador, Carolina, Aparicio-Trejo O.E., et al.2019INTERNATIONAL JOURNAL OF MOLECULAR SCIENCESWoS-id: 000498822800027
Scopus-id: 2-s2.0-85073104881
2223
9Distal renal tubular acidosis in two children with acquired hypothyroidismCoautor: Escobar-Perez, Laura, Guerra-Hernandez, Norma E., Ordaz-Lopez, Karen V., Vargas-Poussou, Rosa, et al.2018NefrologiaWoS-id: 000450879700011
Scopus-id: 2-s2.0-85057083262
11
10Immunolocalization of hyperpolarization-activated cationic HCN1 and HCN3 channels in the rat nephron: regulation of HCN3 by potassium dietsCoautor: Escobar, Laura I., Lopez-Gonzalez, Zinaeli, Ayala-Aguilera, Cosete, Martinez-Morales, Flavio, et al.2016HISTOCHEMISTRY AND CELL BIOLOGYWoS-id: 000369327600004
Scopus-id: 2-s2.0-84954361102
67
11Case report of renal tubular acidosis and misdiagnosedCoautor: Escobar, Laura, Medeiros, Mara, Enciso, Sandra, Maria Hernandez, Ana, et al.2016NefrologiaWoS-id: 000377099000021
Scopus-id: 2-s2.0-84978982713
11
12Extracellular Cl- regulates human SO4 (2-)/anion exchanger SLC26A1 by altering pH sensitivity of anion transportCoautor: Escobar, Laura I., Wu, Meng, Heneghan, John F., Vandorpe, David H., et al.2016PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGYWoS-id: 000380241000002
Scopus-id: 2-s2.0-84964424979
1314
13Mutations in ATP6V1B1 and ATP6V0A4 genes cause recessive distal renal tubular acidosis in Mexican families1ᵉʳ autor: Escobar L.I., Simian C., Treard C., Hayek D., et al.2016Molecular Genetics & Genomic MedicineWoS-id: 000394441700008
Scopus-id: 2-s2.0-85016972748
2121
14Case reports and misdiagnosis of renal tubular acidosisCoautor: Escobar L., Medeiros M., Enciso S., Hernández A.M., et al.2016NefrologiaWoS-id: 000377099000021
Scopus-id: 2-s2.0-85044303151
11
15DISTAL RENAL TUBULAR ACIDOSIS SCREENING BY URINARY ACIDIFICATION TESTING IN MEXICAN CHILDRENCoautor: EscobarPerez, L, GuerraHernandez, NE, OrdazLopez, KV, GomezTenorio, C, et al.2015REVISTA DE INVESTIGACION CLINICA-CLINICAL AND TRANSLATIONAL INVESTIGATIONWoS-id: 000358392500006
Scopus-id: 2-s2.0-85020668012
68
16In relation to the article: Utility of two-hour urine collection test for the diagnosis of the type of renal tubular acidosisCoautor: Escobar Perez, Laura, Garcia Nieto, Victor Manuel, Exeni, Ramon, Matos Martinez, Mario, et al.2015ACTA PEDIATRICA DE MEXICOWoS-id: 000370326400010
Scopus-id: 2-s2.0-85020654500
00
17Differential expression of the Kv1 voltage-gated potassium channel family in the rat nephronCoautor: Escobar, LI, Carrisoza-Gaytan, R, Salvador, C, Diaz-Bello, B2014JOURNAL OF MOLECULAR HISTOLOGYWoS-id: 000342116200010
Scopus-id: 2-s2.0-85027934530
88
18Clinical and biochemical findings in Mexican patients with distal renal tubular acidosisCoautor: Escobar-Pérez L., Guerra-Hernández N., Matos-Martínez M., Ordaz-López K.V., et al.2014REVISTA DE INVESTIGACION CLINICA-CLINICAL AND TRANSLATIONAL INVESTIGATIONWoS-id: 000352520500002
Scopus-id: 2-s2.0-84938092791
77
19Differential expression of the Kv1 voltage-gated potassium channel family in the rat nephronCoautor: Escobar L.I., Carrisoza-Gaytán R., Salvador C., Diaz-Bello B.2014JOURNAL OF MOLECULAR HISTOLOGYScopus-id: 2-s2.0-84929130486
00
20Distal renal tubular acidosis: A hereditary disease with an inadequate urinary H+ excretion [La acidosis tubular renal distal: Una enfermedad hereditaria en la que no se pueden eliminar los hidrogeniones]1ᵉʳ autor: Escobar L., Mejía N., Gil H., Santos F.2013NefrologiaWoS-id: 000319716900001
Scopus-id: 2-s2.0-84878066999
2431
21The Polarization of the G-Protein Activated Potassium Channel GIRK5 to the Vegetal Pole of Xenopus laevis Oocytes Is Driven by a Di-Leucine MotifCoautor: Escobar, LI, Diaz-Bello, B, Rangel-Garcia, CI, Salvador, C, et al.2013PLOS ONEWoS-id: 000320362700100
Scopus-id: 2-s2.0-84878029139
65
22Renal tubular acidosis in children: State of the art, diagnosis and treatment2ᵒ autor: Escobar L., Muñoz-Arizpe R., Medeiros M.2013BOLETIN MEDICO DEL HOSPITAL INFANTIL DE MEXICOScopus-id: 2-s2.0-84879342510
06
23Soft-Soft Interactions in the Protein-Protein Recognition Process: The K+ Channel-Charybdotoxin CaseCoautor: Escobar L.I., Aparicio F., González-Rivas N., Ireta J., et al.2012INTERNATIONAL JOURNAL OF QUANTUM CHEMISTRYWoS-id: 000309995600010
Scopus-id: 2-s2.0-84867742565
44
24Over-diagnosis of renal tubular acidosis in Mexico2ᵒ autor: Escobar L., Munoz-Arizpe, R, Medeiros M.2012REVISTA DE INVESTIGACION CLINICA-CLINICAL AND TRANSLATIONAL INVESTIGATIONWoS-id: 000311258700010
Scopus-id: 2-s2.0-84869790469
812
25The hyperpolarization-activated cyclic nucleotide-gated HCN2 channel transports ammonium in the distal nephronCoautor: Escobar L.I., Carrisoza-Gaytán R., Rangel C., Salvador C., et al.2011KIDNEY INTERNATIONALWoS-id: 000295406600008
Scopus-id: 2-s2.0-80053566319
2327
26A modified dileucine motif mediates the internalization of a G-protein activated inward potassium channelCoautor: Escobar, L, Rangel, CI, Diaz-Bello, B, Padilla, T, et al.2010FASEB JOURNALWoS-id: 000208675507560
00
27Expression and immunolocalization of ERG1 potassium channels in the rat kidneyCoautor: Escobar L.I., Carrisoza R., Salvador C., Bobadilla N.A., et al.2010HISTOCHEMISTRY AND CELL BIOLOGYWoS-id: 000273745800005
Scopus-id: 2-s2.0-77950359846
1111
28Potassium secretion by voltage-gated potassium channel Kv1.3 in the rat kidneyCoautor: Escobar, LI, Carrisoza-Gaytan, R, Salvador, C, Satlin, LM, et al.2010AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGYWoS-id: 000278887300028
Scopus-id: 2-s2.0-77953827424
1618
29Peptide sr11a from Conus spurius is a novel peptide blocker for Kv1 potassium channelsCoautor: Escobar L.I., Aguilar M.B., Pérez-Reyes L.I., López Z., et al.2010PeptidesWoS-id: 000279078700009
Scopus-id: 2-s2.0-77952541919
2428
30Folded Conformations of Maitotoxin2ᵒ autor: Escobar L., Matus M.H., Galván M.2008Journal Of The Mexican Chemical SocietyWoS-id: 000261932900011
Scopus-id: 2-s2.0-77953845625
00
31Phosphorylation of a tyrosine at the N-terminus regulates the surface expression of GIRK5 homomultimers2ᵒ autor y autor de correspondencia: Escobar L.I., Mora S.I.2005FEBS LETTERSWoS-id: 000229822500009
Scopus-id: 2-s2.0-20444382085
66
32A voltage-gated K+ current in renal inner medullary collecting duct cells1ᵉʳ autor: Escobar L.I., Martínez-Téllez J.C., Salas M., Castilla S.A., et al.2004AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGYWoS-id: 000220032900026
Scopus-id: 2-s2.0-2142715270
2626
33Basal activity of GIRK5 isoformsCoautor: Escobar L.I., Salvador C., Mora S.I., Ordaz B., et al.2003LIFE SCIENCESWoS-id: 000180640000007
Scopus-id: 2-s2.0-0037435805
12
34On the existence of electronic states confined by charged groups in proteinsCoautor: Escobar L., Aparicio F., Ireta J., Rojo A., et al.2003JOURNAL OF PHYSICAL CHEMISTRY BWoS-id: 000181100500029
Scopus-id: 2-s2.0-84962432280
1617
35Functional properties of a truncated recombinant GIRK5 potassium channelCoautor: Escobar L.I., Salvador C., Martinez M., Mora S.Ivonne, et al.2001BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANESWoS-id: 000168735500013
Scopus-id: 2-s2.0-0035795731
1010
36Modulation of a calcium-activated chloride current by MaitotoxinCoautor: Escobar L.I., Martínez M., Salvador C., Farias J.M., et al.1999ToxiconWoS-id: 000078437400009
Scopus-id: 2-s2.0-2542508814
47
37Maitotoxin, a cationic channel activator1ᵉʳ autor: Escobar L.I., Salvador C., Martinez M., Vaca L.1998NeurobiologyScopus-id: 2-s2.0-0032463344
048
38Alcohols inhibit a cloned potassium channel at a discrete saturable site: Insights into the molecular basis of general anesthesiaCoautor: Escobar L., Covarrubias M., Vyas T.B., Wei A.1995JOURNAL OF BIOLOGICAL CHEMISTRYWoS-id: A1995RP70300036
Scopus-id: 2-s2.0-0029112894
8087
39Permeation properties and differential expression across the auditory receptor epithelium of an inward rectifier K+ channel cloned from the chick inner ear2ᵒ autor: Escobar L., Navaratnam D.S., Covarrubias M., Carl Oberholtzer J.1995JOURNAL OF BIOLOGICAL CHEMISTRYWoS-id: A1995RP70300009
Scopus-id: 2-s2.0-0029147815
4439
40Influence of protein surface charge on the bimolecular kinetics of a potassium channel peptide inhibitor1ᵉʳ autor: Escobar L., Root M.J., MacKinnon R.1993BIOCHEMISTRYWoS-id: A1993LN44200024
Scopus-id: 2-s2.0-0027219545
6057
41Noxiustoxin and leiurutoxin III, two homologous peptide toxins with binding properties to synaptosomal membrane K+ channels.Coautor: Escobar L., Valdivia H.H., Martin B.M., Possani L.D.1992Biochemistry InternationalWoS-id: A1992JQ09400001
Scopus-id: 2-s2.0-0026775567
1818
42Respiratory electron transfer activity in an asolectin-isooctane reverse micellar system1ᵉʳ autor: Escobar L., Escamilla E.1992BiochimieWoS-id: A1992HL54800007
Scopus-id: 2-s2.0-0026574090
24
43On the application of the Clark oxygen electrode to the study of enzyme kinetics in apolar solvents: The catalase reaction1ᵉʳ autor: Escobar L., Salvador C., Contreras M., Edgardo Escamilla J.1990ANALYTICAL BIOCHEMISTRYWoS-id: A1990CG86800025
Scopus-id: 2-s2.0-0025177093
1822
44Total assignment of 13C and 1H spectra of three isomeric triterpenol derivatives by 2D NMR: an investigation of the potential utility of 1H chemical shifts in structural investigations of complex natural productsCoautor: Escobar L.I., Reynolds W.F., McLean S., Poplawski J., et al.1986TetrahedronWoS-id: A1986D079100006
Scopus-id: 2-s2.0-3242690216
208211
45High-performance liquid chromatographic study of Casimiroa edulis. II. Determination of furocoumarinsCoautor: Escobar L.I., Enríquez R.G., Romero M.L., Joseph-Nathan P., et al.1984JOURNAL OF CHROMATOGRAPHY AWoS-id: A1984SN25000026
Scopus-id: 2-s2.0-0021227912
1819
46Comparative effect of zoapatle (Montanoa tomentosa) products and of verapamil on the in vitro uterine contractility of ratCoautor: Escobar L., Bejar E., Lozoya X., Enriquez R.1984Archivos De Investigación MédicaWoS-id: A1984C986100005
Scopus-id: 2-s2.0-0021701023
1011
47Determination of grandiflorenic acid in organic and aqueous extracts of Montanoa tomentosa (zoapatle) by reversed-phase high-performance liquid chromatography2ᵒ autor: Escobar L.I., Enríquez R.G., Romero M.L., Chávez M.A., et al.1983JOURNAL OF CHROMATOGRAPHY AWoS-id: A1983QJ24000039
Scopus-id: 2-s2.0-0000586605
2015
48High-performance liquid chromatographic study of casimiroa edulis. I. Determination of imidazole derivatives and rutin in aqueous and organic extracts2ᵒ autor: Escobar L.I., Romero M.L., Lozoya X., Enríquez R.G.1983JOURNAL OF CHROMATOGRAPHY AWoS-id: A1983RZ95600021
Scopus-id: 2-s2.0-0542367907
1621
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No se encuentran registros en la base de datos de obras con ISBN (Indautor).

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No se encuentran registros en la base de datos de patentes.

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No se encuentran registros en la base de datos de libros completos (Humanindex).

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Capítulos de libros (Humanindex)