MARIANA SEGOVIA MENDOZA



DATOS GENERALES
Nombre completo   MARIANA SEGOVIA MENDOZA
Máximo nivel de estudios   DOCTORADO
Antigüedad académica en la UNAM   5 años
NOMBRAMIENTOS
Vigente   PROFESOR DE CARRERA TITULAR A TC No Definitivo
Dirección General de Asuntos del Personal Académico
Desde 01-03-2024
PROFESOR DE CARRERA ASOCIADO B TC No Definitivo
Facultad de Medicina
Desde 16-01-2020 hasta 28-02-2024
POSDOCTOR TC No Definitivo
Instituto de Biotecnología
Desde 01-03-2018 hasta 28-02-2019
ESTIMULOS, PROGRAMAS, PREMIOS Y RECONOCIMIENTOS
* SNI I2022 - 2024
* SNI C2020 - 2021
* EQUIVALENCIA PRIDE B2020 - 2024

INFORMACIÓN DE PUBLICACIONES
Firmas  
Mariana S.-M. Mariana, Segovia-Mendoza Mendoza M.S. Segovia-Mendoza M. Segovia-Mendoza, M Segovia-Mendoza, Mariana
ID's SCOPUS  
56458990900
ORCID's  
0000-0002-4783-9474
Áreas de conocimiento  
Biochemistry and molecular biology Developmental biology Endocrinology and metabolism Immunology Medicine, general and internal
Microbiology Multidisciplinary sciences Oncology Pharmacology and pharmacy Public, environmental and occupational health
Reproductive biology Toxicology Clinical biochemistry Environmental science (miscellaneous) Health, toxicology and mutagenesis
Immunology and allergy Immunology and microbiology (miscellaneous) Medicine (miscellaneous) Multidisciplinary Obstetrics and gynecology
Oncology Organic chemistry Pediatrics, perinatology and child health Pharmaceutical science Pharmacology (medical)
Reproductive medicine Spectroscopy Toxicology
Coautorías con entidades de la UNAM  
  • Centro de Ciencias de la Atmósfera
  • Instituto de Investigaciones Biomédicas
  • Instituto de Química
  • Instituto de Biotecnología
  • Instituto de Neurobiología en Querétaro, Querétaro
  • Instituto de Ciencias de la Atmósfera y Cambio Climático
  • Facultad de Ciencias
  • Facultad de Medicina
  • Facultad de Química
  • Facultad de Medicina Veterinaria y Zootecnia
  • Dirección General de Asuntos del Personal Académico
Revistas en las que ha publicado  (21):
  1. AMERICAN JOURNAL OF CANCER RESEARCH, Estados Unidos America (2020)
  2. BIOLOGICAL & PHARMACEUTICAL BULLETIN, Japón (2021)
  3. Birth Defects Research, Reino Unido (2020)
  4. Cancers, Suiza (2019)
  5. CHEMICAL BIOLOGY & DRUG DESIGN, Estados Unidos America (2024)
  6. ENVIRONMENTAL RESEARCH, Estados Unidos America (2020)
  7. ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY, Países Bajos (2024)
  8. Frontiers in Bioscience-Landmark, Estados Unidos America (2021)
  9. FRONTIERS IN IMMUNOLOGY, Suiza (2019)
  10. Frontiers in Oncology, Suiza (2022)
  11. INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, Suiza (2022)
  12. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, Suiza (2021, 2022, 2023)
  13. JOURNAL OF IMMUNOLOGY RESEARCH, Estados Unidos America (2019, 2021)
  14. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH, Estados Unidos America (2019)
  15. JOURNAL OF REPRODUCTIVE IMMUNOLOGY, Irlanda (2024)
  16. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, Reino Unido (2021, 2025)
  17. Neurotherapeutics, Estados Unidos America (2025)
  18. Pathogens, Suiza (2022)
  19. Placenta, Reino Unido (2022)
  20. PLOS ONE, Estados Unidos America (2019)
  21. REVISTA DE INVESTIGACION CLINICA-CLINICAL AND TRANSLATIONAL INVESTIGATION, México (2019)


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Documentos indexados (WoS y Scopus)

# Título del documento Autores Año Revista Fuente Citas WoS Citas Scopus
1Clavulanic acid prevents paclitaxel-induced neuropathic pain through a systemic and central anti-inflammatory effect in miceCoautor: Segovia-Mendoza M., Balcazar-Ochoa L.G., Ángeles-López G.E., Chavarría A., et al.2025NeurotherapeuticsWoS-id: 001438488400001
Scopus-id: 2-s2.0-85214585618
00
2GPER1 activation by estrogenic compounds in the inflammatory profile of breast cancer cells1ᵉʳ autor: Mariana S.-M., Brenda R.-P., Heriberto P.-G., Cristina L., et al.2025JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGYWoS-id: 001448281300001
Scopus-id: 2-s2.0-85209590304
00
3Effects of calcitriol upon TGF-ßs and their receptors in trophoblast cellsCoautor: Segovia-Mendoza M., Noyola-Martínez N., Chirinos M., Ramírez-Camacho I., et al.2024JOURNAL OF REPRODUCTIVE IMMUNOLOGYWoS-id: 001146416100001
Scopus-id: 2-s2.0-85180613572
00
4Cardiovascular disrupting effects of bisphenols, phthalates, and parabens related to endothelial dysfunction: Review of toxicological and pharmacological mechanismsCoautor y autor de correspondencia: Segovia-Mendoza M., Lemini C., Silveyra P.2024ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGYWoS-id: 001206624100001
Scopus-id: 2-s2.0-85187553279
22
5Evaluation of doxorubicin and ß-lapachone analogs as anticancer agents, a biological and computational studyCoautor: Segovia-Mendoza, M, Mercado-Sánchez, I, López, J, Chávez-Rocha, R, et al.2024CHEMICAL BIOLOGY & DRUG DESIGNWoS-id: 001275832800001
Scopus-id: 2-s2.0-85199580110
22
6The Phytochemical a-Mangostin Inhibits Cervical Cancer Cell Proliferation and Tumor Growth by Downregulating E6/E7-HPV Oncogenes and KCNH1 Gene ExpressionCoautor: Segovia-Mendoza, Mariana, Diaz, Lorenza, Bernadez-Vallejo, Samantha V., Vargas-Castro, Rafael, et al.2023INTERNATIONAL JOURNAL OF MOLECULAR SCIENCESWoS-id: 000932820900001
Scopus-id: 2-s2.0-85147894253
1313
7Environmental Pollution to Blame for Depressive Disorder?1ᵉʳ autor: Segovia-Mendoza, Mariana, Palacios-Arreola, Margarita Isabel, Pavon, Lenin, Becerril, Luis Enrique, et al.2022INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTHWoS-id: 000755537300001
Scopus-id: 2-s2.0-85123752627
35
8The Endocrine Disruptor Compound Bisphenol-A (BPA) Regulates the Intra-Tumoral Immune Microenvironment and Increases Lung Metastasis in an Experimental Model of Breast CancerCoautor: Segovia-Mendoza, Mariana, Palacios-Arreola M.I., Moreno-Mendoza N.A., Nava-Castro K.E., et al.2022INTERNATIONAL JOURNAL OF MOLECULAR SCIENCESWoS-id: 000774199000001
Scopus-id: 2-s2.0-85125111697
1315
9Sexual Dimorphism of the Neuroimmunoendocrine Response in the Spleen during a Helminth Infection: A New Role for an Old Player?Coautor: Segovia-Mendoza, Mariana, Nava-Castro K.E., Pavon, Lenin, Becerril-Villanueva L.E., et al.2022PathogensWoS-id: 000774264200001
Scopus-id: 2-s2.0-85125854759
33
10EFFECTS OF CALCITRIOL UPON TGF-BS AND THEIR RECEPTORS IN TROPHOBLAST CELLSCoautor: Mariana, Segovia-Mendoza, Ixchel, Ramirez-Camacho, Joselin, Escamilla-Bucio, Juan Pablo, Aragon-Hernandez, et al.2022PlacentaWoS-id: 000802569200074
00
11Association of Serum Levels of Plasticizers Compounds, Phthalates and Bisphenols, in Patients and Survivors of Breast Cancer: A Real Connection?1ᵉʳ autor: Segovia-Mendoza M., Palacios-Arreola M.I., Monroy-Escamilla L.M., Soto-Piña A.E., et al.2022INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTHWoS-id: 000823532000001
Scopus-id: 2-s2.0-85133142858
79
12The Interplay of GPER1 with 17 beta-Aminoestrogens in the Regulation of the Proliferation of Cervical and Breast Cancer Cells: A Pharmacological Approach1ᵉʳ autor: Segovia-Mendoza, Mariana, Mirzaei, Elahe, Prado-Garcia, Heriberto, Miranda, Luis D., et al.2022INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTHWoS-id: 000866849600001
Scopus-id: 2-s2.0-85139812571
24
13Intratumoral Treatment with 5-Androstene-3ß, 17a-Diol Reduces Tumor Size and Lung Metastasis in a Triple-Negative Experimental Model of Breast CancerCoautor: Segovia-Mendoza M., Ruiz Manzano R.A., Nava-Castro K.E., Palacios-Arreola M.I., et al.2022INTERNATIONAL JOURNAL OF MOLECULAR SCIENCESWoS-id: 000867759000001
Scopus-id: 2-s2.0-85139812717
00
14Editorial: Exploring the breast tumor microenvironment: Association to metastasis, novel risk factors and novel treatments and immunotherapies2ᵒ autor: Segovia-Mendoza, Mariana, Nava-Castro, Karen Elizabeth, Morales-Montor, Jorge2022Frontiers in OncologyWoS-id: 000901789100001
Scopus-id: 2-s2.0-85144254976
00
15Determining Factors in the Therapeutic Success of Checkpoint Immunotherapies against PD-L1 in Breast Cancer: A Focus on Epithelial-Mesenchymal Transition Activation1ᵉʳ autor: Segovia-Mendoza, Mariana, Romero-Garcia, Susana, Lemini, Cristina, Prado-Garcia, Heriberto2021JOURNAL OF IMMUNOLOGY RESEARCHWoS-id: 000611571900001
Scopus-id: 2-s2.0-85099650744
1110
16Potential estrogenic properties of 17ß-hydroxy-ethylimine estradiol derivative targeted to menopause stage2ᵒ autor: Segovia-Mendoza M., Jimenez-Sánchez G.L., Figueroa A., Lemini C.2021BIOLOGICAL & PHARMACEUTICAL BULLETINWoS-id: 000620798500010
Scopus-id: 2-s2.0-85098630178
00
17Regulation of anti-tumorigenic pathways by the combinatory treatment of calcitriol and TGF-beta in PC-3 and DU145 cellsCoautor: Segovia-Mendoza, Mariana, Garcia-Olivares, Mitzi, Romero-Cordoba, Sandra, Ortiz-Sanchez, Elizabeth, et al.2021JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGYWoS-id: 000636293300008
Scopus-id: 2-s2.0-85101342493
56
18Bisphenol A: an endocrine-disruptor compound that modulates the immune response to infections2ᵒ autor: Mendoza M.S., Araiza V.H.D.R., Castro K.E.N., Cruz S.M., et al.2021Frontiers in Bioscience-LandmarkWoS-id: 000641416300006
Scopus-id: 2-s2.0-85092886001
2022
19Environmental parasitology and its impact on the host nueroimmunoendocrine networkCoautor: Segovia-Mendoza, Mariana, Gomez de Leon, Carmen T., Ostoa-Saloma, Pedro, Del Rio-Araiza, Victor H., et al.2021Frontiers in Bioscience-LandmarkWoS-id: 000641419000002
Scopus-id: 2-s2.0-85092885753
45
20Antitumoral effects of dovitinib in triple-negative breast cancer are synergized by calcitriol in vivo and in vitroCoautor: Segovia-Mendoza, Mariana, Garcia-Quiroz, Janice, Cardenas-Ochoa, Nohemi, Garcia-Becerra, Rocio, et al.2021JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGYWoS-id: 000703194900005
Scopus-id: 2-s2.0-85113470073
79
21Combinations of calcitriol with anticancer treatments for breast cancer: An update1ᵉʳ autor: Segovia-Mendoza M., García-Quiroz J., Díaz L., García-Becerra R.2021INTERNATIONAL JOURNAL OF MOLECULAR SCIENCESWoS-id: 000735321500001
Scopus-id: 2-s2.0-85120903478
2625
22Perinatal exposure to bisphenol A increases in the adulthood of the offspring the susceptibility to the human parasite Toxocara canisCoautor: Segovia-Mendoza, Mariana, Del Rio-Araiza, Victor H., Palacios-Arreola, I, Margarita, Nava-Castro, Karen E., et al.2020ENVIRONMENTAL RESEARCHWoS-id: 000526178000079
Scopus-id: 2-s2.0-85082107362
1212
23How microplastic components influence the immune system and impact on children health: Focus on cancer1ᵉʳ autor: Segovia-Mendoza, Mariana, Nava-Castro, Karen E., Palacios-Arreola, Margarita I., Garay-Canales, Claudia, et al.2020Birth Defects ResearchWoS-id: 000556191800001
Scopus-id: 2-s2.0-85089101159
5664
24An organotin indomethacin derivative inhibits cancer cell proliferation and synergizes the antiproliferative effects of lapatinib in breast cancer cells1ᵉʳ autor: Segovia-Mendoza, Mariana, Camacho-Camacho, Carlos, Rojas-Oviedo, Irma, Prado-Garcia, Heriberto, et al.2020AMERICAN JOURNAL OF CANCER RESEARCHWoS-id: 000583897900018
60
25The chemical environmental pollutants BPA and BPS induce alterations of the proteomic profile of different phenotypes of human breast cancer cells: A proposed interactome1ᵉʳ autor: Segovia-Mendoza M., Gómez de León C.T., García-Becerra R., Ambrosio J., et al.2020ENVIRONMENTAL RESEARCHWoS-id: 000587971600008
Scopus-id: 2-s2.0-85092224337
2627
26Immune Tumor Microenvironment in Breast Cancer and the Participation of Estrogens and Its Receptors Into Cancer Physiopathology1ᵉʳ autor: Segovia-Mendoza, Mariana, Morales-Montor, Jorge2019FRONTIERS IN IMMUNOLOGYWoS-id: 000459974400001
Scopus-id: 2-s2.0-85063271580
97101
27Breast Cancer Metastasis: Are Cytokines Important Players during Its Development and Progression?Coautor: Segovia-Mendoza, Mariana, Méndez-García L.A., Nava-Castro K.E., Ochoa-Mercado T.D.L., et al.2019JOURNAL OF INTERFERON AND CYTOKINE RESEARCHWoS-id: 000463009500005
Scopus-id: 2-s2.0-85059829128
5458
28Calcitriol Inhibits the Proliferation of Triple-Negative Breast Cancer Cells through a Mechanism Involving the Proinflammatory Cytokines IL-1 beta and TNF-alphaCoautor: Segovia-Mendoza, Mariana, Martinez-Reza, Isela, Diaz, Lorenza, Barrera, David, et al.2019JOURNAL OF IMMUNOLOGY RESEARCHWoS-id: 000465298200001
Scopus-id: 2-s2.0-85066878363
3940
29ASTEMIZOLE, AN INHIBITOR OF ETHER-À-GO-GO-1 POTASSIUM CHANNEL, INCREASES THE ACTIVITY OF THE TYROSINE KINASE INHIBITOR GEFITINIB IN BREAST CANCER CELLSCoautor: Segovia-Mendoza M., García-Quiroz J., González-González M.E., Díaz L., et al.2019REVISTA DE INVESTIGACION CLINICA-CLINICAL AND TRANSLATIONAL INVESTIGATIONWoS-id: 000476468900005
Scopus-id: 2-s2.0-85067821579
1617
30Sex-associated protective effect of early bisphenol-A exposure during enteric infection with Trichinella spiralis in miceCoautor: Segovia-Mendoza, Mariana, Nava-Castro K.E., Solleiro-Villavicencio, Helena, del Río-Araiza V.H., et al.2019PLOS ONEWoS-id: 000484947800018
Scopus-id: 2-s2.0-85069565848
66
31Synergistic antitumorigenic activity of calcitriol with curcumin or resveratrol is mediated by angiogenesis inhibition in triple negative breast cancer xenograftsCoautor: Segovia-Mendoza, Mariana, Garcia-Quiroz, Janice, Garcia-Becerra, Rocio, Santos-Cuevas, Clara, et al.2019CancersWoS-id: 000502290100121
Scopus-id: 2-s2.0-85074979868
4950
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Documentos no indexados (Humanindex)

# Título del documento ISSN Revista Año Fuente
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Capítulos de libros (WoS y Scopus)

# Título del capítulo Título del libro Autores Alcance Año ISBN Fuente
1Hormonal bias in cardiovascular diseases: A focus on the atherosclerotic processUnderstanding Sexual DimorphismSegovia-Mendoza M., Lemini C., Morales-Montor J., Capítulo de un Libro20239798886979459Scopus-id: 2-s2.0-85171606134
2Modulation of the Innate Immune System by the Endocrine Disrupting Compounds Bisphenol A (BPA) and PhtalathesThe Innate Immune System In Health And Disease: From The Lab Bench Work To Its Clinical Implications: Volume 2Nava-Castro K.E., Palacios-Arreola M.I., Del Río-Araiza V.H., et al.Capítulo de un Libro20229781685076498Scopus-id: 2-s2.0-85136719167
3Immunoconjugates as immune canoes to kill breast cancer cellsImmunotherapy In Resistant Cancer: From The Lab Bench Work To Its Clinical PerspectivesSegovia-Mendoza M., Lemini C., García-Becerra R., et al.Capítulo de un Libro20209780128220283Scopus-id: 2-s2.0-85147600645
4PrefaceImmunotherapy In Resistant Cancer: From The Lab Bench Work To Its Clinical PerspectivesMorales-Montor J., Segovia-Mendoza M., Editorial Material20209780128220283Scopus-id: 2-s2.0-85147600366
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No se encuentran registros en la base de datos de obras con ISBN (Indautor).

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Proyectos

# Nombre Participantes Convocatoria Fecha Inicio Fecha Fin
1Evaluación en sílico de las interacciones de los 17ß-aminoestrógenos prolame, butolame y pentolame, con el receptor de estrógenos membranal (GPER), el receptor de angiotensina II (ATI), y la enzima convertidora de angiotensina (ECA) mediante estudios de simulación molecular.MARIANA SEGOVIA MENDOZA,
Ingresos Propios04-05-202104-05-2024
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Participación en Comités de Tesis

# Título del documento Tipo de Tesis Sinodales Autores Año Entidad Url
1Efecto del 17 beta aminoestrógeno pentolame en el perfil de citocinas pro y antiinflamatorias en células de cáncer de mamaTesis de LicenciaturaMARIANA SEGOVIA MENDOZA; LEONOR AGUILAR SANTELISES; RODRIGO ANIBAL MATEOS NAVA; Reyes Plata, Brenda; 2023Facultad de Estudios Superiores "Zaragoza", Facultad de Medicina,
2"Implicación del receptor de estrógenos membranal GPER1 en procesos de migración y proliferación celular en cáncer de mama"Tesis de LicenciaturaMARIANA SEGOVIA MENDOZA; Barceló Márquez, Guillermo Roberto; 2023Facultad de Medicina,
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Docencia Impartida

# Entidad Nivel Asignatura Año Semestre Alumnos
1Facultad de MedicinaLicenciaturaFARMACOLOGIA20232024-126
2Facultad de MedicinaLicenciaturaFARMACOLOGIA20222023-038
3Facultad de MedicinaLicenciaturaFARMACOLOGIA20212022-043
4Facultad de MedicinaLicenciaturaFARMACOLOGIA20202021-038
5Facultad de MedicinaLicenciaturaFARMACOLOGIA20192020-033
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No se encuentran registros en la base de datos de patentes.

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No se encuentran registros en la base de datos de libros completos (Humanindex).

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Capítulos de libros (Humanindex)

# Título del libro Título del capítulo ISBN Editorial Año Fuente