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Título del libro: Molecular Medical Microbiology: Second Edition
Título del capítulo: Towards a Synthesis of Population Genomics and Epidemiology: Next-Generation Sequencing of Bacterial Pathogens

Autores UNAM:
SANTIAGO CASTILLO RAMIREZ;
Autores externos:

Idioma:
Inglés
Año de publicación:
2014
Palabras clave:

Ecology of pathogens; Evolutionary genetics; Genome dynamics; Population genetics


Resumen:

The advent of next-generation sequencing technology has provided unprecedented detail as to the micro-evolutionary processes impacting on bacterial genomes. These data are also leading to a powerful synthesis between evolutionary genetics, population biology, ecology and epidemiology: such a holistic approach is necessary to understand the emergence and spread of bacterial pathogens. Here the recent advances made in understanding genome dynamics within this broader epidemiological context are reviewed, and the challenges and opportunities bestowed by next-generation sequencing in the future are discussed. © 2015, 2002 Elsevier Ltd. All rights reserved.


Entidades citadas de la UNAM: