OCTAVIO TONATIUH RAMIREZ REIVICH



DATOS GENERALES
Nombre completo   OCTAVIO TONATIUH RAMIREZ REIVICH
Máximo nivel de estudios   POSDOCTORADO
Antigüedad académica en la UNAM   35 años
NOMBRAMIENTOS
Vigente   INVESTIGADOR TITULAR C TC Definitivo
Instituto de Biotecnología
Desde 01-01-2008 (fecha inicial de registros en el SIIA)
ESTIMULOS, PROGRAMAS, PREMIOS Y RECONOCIMIENTOS
* SNI EméritoVIGENTE
* SNI III - 2025
* PRIDE D - 2024
* RDUNJA Innovación tecnológica y diseño industrial2000
* PUN Innovación tecnológica y diseño industrial2010

INFORMACIÓN DE PUBLICACIONES
Firmas  
Ramírez O.T. Ramirez O.T. Ramirez, O Ramirez, O. T. Ramirez, Octavio T. Ramirez, OT
ID's SCOPUS  
7102090460
Áreas de conocimiento  
Biochemical research methods Biochemistry & molecular biology Biology Biotechnology & applied microbiology Biotechnology and applied microbiology
Cell biology Chemistry, analytical Endocrinology and metabolism Engineering, chemical Food science & technology
Food science and technology Materials science, multidisciplinary Mathematical and computational biology Medicine, research & experimental Medicine, research and experimental
Metallurgy and metallurgical engineering Microbiology Multidisciplinary sciences Physics, applied Physics, multidisciplinary
Plant sciences Virology Agricultural and Biological Sciences (miscellaneous) Agronomy and crop science Applied microbiology and biotechnology
Biochemistry Biochemistry, Genetics and Molecular Biology (miscellaneous) Biotechnology Clinical Biochemistry Chemical Engineering (miscellaneous)
Chemistry (miscellaneous) Environmental Engineering Food Science Genetics Insect science
Materials Science (miscellaneous) Mechanical Engineering Medicine (miscellaneous) Modeling and simulation Molecular biology
Multidisciplinary Physical and theoretical chemistry Physics and astronomy (miscellaneous) Physiology (medical) Process Chemistry and Technology
Veterinary (miscellaneous) Virology
Coautorías con entidades de la UNAM  
  • Consejo Técnico y Coordinación de la Investigación Científica
  • Centro de Ciencias Genómicas
  • Centro de Ciencias Aplicadas y Desarrollo Tecnológico
  • Instituto de Investigaciones Biomédicas
  • Instituto de Química
  • Instituto de Ciencias Nucleares
  • Instituto de Biotecnología
  • Instituto de Ciencias Físicas
  • Instituto de Energías Renovables
  • Instituto de Ciencias Aplicadas y Tecnología
  • Facultad de Ciencias
  • Facultad de Medicina
  • Facultad de Medicina Veterinaria y Zootecnia
  • Facultad de Estudios Superiores "Cuautitlán"
  • Coordinación de Estudios de Posgrado
Revistas en las que ha publicado  (57):
  1. Abstracts Of Papers Of The American Chemical Society, Estados Unidos America (2012, 2013)
  2. Advances in Biochemical Engineering-Biotechnology, Estados Unidos America (2021)
  3. ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS, Países Bajos (2022)
  4. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, Estados Unidos America (2008)
  5. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, Estados Unidos America (1997)
  6. ARCHIVES OF VIROLOGY, Austria (2014)
  7. BIOCHEMICAL ENGINEERING JOURNAL, Países Bajos (2004, 2005, 2009, 2011, 2013, 2018)
  8. Bioelectrochemistry, Suiza (2019)
  9. Bioengineered Bugs, (2011)
  10. Biotechniques, Estados Unidos America (2003)
  11. BIOTECHNOL TECH, (1987)
  12. BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY, Estados Unidos America (2005, 2007)
  13. BIOTECHNOLOGY AND BIOENGINEERING, Estados Unidos America (1989, 1990, 1997, 2001, 2002, 2004, 2005, 2006, 2008, 2009, 2016, 2020, 2023)
  14. BIOTECHNOLOGY JOURNAL, Alemania (2011)
  15. BIOTECHNOLOGY LETTERS, Países Bajos (1995, 1996, 2001, 2021)
  16. BIOTECHNOLOGY PROGRESS, Estados Unidos America (1992, 2001, 2005, 2011)
  17. BMC BIOTECHNOLOGY, Reino Unido (2007)
  18. BMC SYSTEMS BIOLOGY, Reino Unido (2018)
  19. Cell Engineering, Suiza (2015)
  20. CLASSICAL AND QUANTUM GRAVITY, Reino Unido (2025)
  21. Cytotechnology, Países Bajos (1994, 1996, 1998)
  22. Electronic Journal Of Biotechnology, Chile (2020)
  23. Electrophoresis, Alemania (2010)
  24. ENGINEERING IN LIFE SCIENCES, Estados Unidos America (2011, 2016)
  25. ENZYME AND MICROBIAL TECHNOLOGY, Estados Unidos America (1994, 1996, 1998, 2000, 2001, 2003, 2013)
  26. FEBS JOURNAL, Estados Unidos America (2010)
  27. FREE RADICAL BIOLOGY AND MEDICINE, Estados Unidos America (2012, 2025)
  28. Frontiers in Bioengineering and Biotechnology, Suiza (2020)
  29. JOURNAL OF BIOSCIENCE AND BIOENGINEERING, Japón (2014)
  30. JOURNAL OF BIOTECHNOLOGY, Países Bajos (1999, 2006, 2012, 2013, 2017, 2022, 2026)
  31. JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY, Estados Unidos America (2010)
  32. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, Países Bajos (2005, 2006, 2011)
  33. JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY, Alemania (2012)
  34. JOURNAL OF MATERIALS SCIENCE, Estados Unidos America (2019)
  35. JOURNAL OF MOLECULAR MICROBIOLOGY AND BIOTECHNOLOGY, Suiza (2005, 2007)
  36. JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY, Estados Unidos America (2013)
  37. Journal of Scanning Probe Microscopy, Estados Unidos America (2008)
  38. JOURNAL OF VIROLOGY, Estados Unidos America (2022)
  39. Langmuir, Estados Unidos America (2014)
  40. METABOLIC ENGINEERING, Estados Unidos America (2006, 2024)
  41. METALS, Suiza (2016)
  42. Methods, Estados Unidos America (2012)
  43. Methods in Molecular Biology, Estados Unidos America (2004, 2012, 2024)
  44. MICROBIAL CELL FACTORIES, Reino Unido (2008, 2010, 2011, 2012, 2013, 2014, 2019, 2024)
  45. MOLECULAR BIOLOGY OF THE CELL, Estados Unidos America (2017)
  46. MOLECULAR BIOTECHNOLOGY, Estados Unidos America (2006)
  47. Nanotechnology, Reino Unido (2013, 2014, 2020)
  48. Nature Biotechnology, Estados Unidos America (1999)
  49. PLANT CELL REPORTS, Estados Unidos America (1997)
  50. PLANT CELL TISSUE AND ORGAN CULTURE, Países Bajos (1997)
  51. PLOS ONE, Estados Unidos America (2016, 2020, 2025)
  52. PROCESS BIOCHEMISTRY, Reino Unido (1994, 2005)
  53. Progress In Biotechnology, (1996)
  54. PROTEIN EXPRESSION AND PURIFICATION, Estados Unidos America (2025)
  55. SCIENTIFIC REPORTS, Reino Unido (2022)
  56. Stem Cells, Estados Unidos America (1998)
  57. Vaccine, Países Bajos (2009, 2014, 2019)


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Documentos indexados (WoS y Scopus)

# Título del documento Autores Año Revista Fuente Citas WoS Citas Scopus
1Comparative analysis of manufacturability and binding of various bispecific antibody architectures2ᵒ autor: Ramirez, OT, Rivera-Castro, JC, Palomares, LA2026JOURNAL OF BIOTECHNOLOGYWoS-id: 001757120100001
Scopus-id: 2-s2.0-105036397987
00
2Molecular characterization of the effects of heat shock on the infection cycle progression and productivity of the baculovirus expression vector systemCoautor: Ramírez, OT, Paz-Cortés, E, Pastor, AR, Salinas-Marín, R, et al.2025PLOS ONEWoS-id: 001459354900009
Scopus-id: 2-s2.0-105001937197
33
3On the unexpected geometrical origin of the algebra of symmetries1ᵉʳ autor: Ramirez, O, Bonder, Y2025CLASSICAL AND QUANTUM GRAVITYWoS-id: 001520251700001
Scopus-id: 2-s2.0-105010028278
00
4Monitoring Golgi redox potential in CHO cells under hypoxia: A comparison of transient and stable roGFP1-iL expressionCoautor: Ramírez, OT, Meza, SW, Contreras, MA, Palomares, LA2025FREE RADICAL BIOLOGY AND MEDICINEWoS-id: 001522338800059
00
5Functional expression of five refolded recombinant variants of RBD from SARS-CoV-2 in Escherichia coliCoautor: Ramírez O.T., Tobón E., Riaño-Umbarila L., Flores H., et al.2025PROTEIN EXPRESSION AND PURIFICATIONWoS-id: 001539850900001
Scopus-id: 2-s2.0-105011255132
11
6Oral administration of a recombinant modified RBD antigen of SARS-CoV-2 as a possible immunostimulant for the care of COVID-19Coautor: Ramirez, OT, Valdez-Cruz, NA, Rosiles-Becerril, D, Martínez-Olivares, CE, et al.2024MICROBIAL CELL FACTORIESWoS-id: 001158375200001
Scopus-id: 2-s2.0-85184531576
00
7Expression in CHO cells of a bacterial biosynthetic pathway producing a small non-ribosomal peptide aldehyde prevents proteolysis of recombinant proteinsCoautor: Ramírez O.T., Guadarrama-Pérez V., Aguilar C., Porras-Sanjuanico A., et al.2024METABOLIC ENGINEERINGWoS-id: 001184962300001
Scopus-id: 2-s2.0-85184523200
33
8One-Step Purification Strategy for Cowpea Chlorotic Mottle Virus-Like Particles Produced by the IC-BEVSCoautor: Ramírez O.T., Martínez A., Porras A., Pastor A.R., et al.2024Methods in Molecular BiologyScopus-id: 2-s2.0-85197682834
01
9Construction of Recombinant Baculoviruses2ᵒ autor: Ramírez O.T., Pastor A.R., Palomares L.A.2024Methods in Molecular BiologyScopus-id: 2-s2.0-85197699965
00
10Mimotope discovery as a tool to design a vaccine against Zika and dengue virusesCoautor: Ramírez O.T., Cuevas-Juárez E., Liñan-Torres A., Hernández C., et al.2023BIOTECHNOLOGY AND BIOENGINEERINGWoS-id: 000971957300001
Scopus-id: 2-s2.0-85153071759
810
11Dengue Virus NS1 Uses Scavenger Receptor B1 as a Cell Receptor in Cultured CellsCoautor: Ramirez, Octavio T., Alcala, Ana C., Maravillas, Jose L., Meza, David, et al.2022JOURNAL OF VIROLOGYWoS-id: 000779305000034
Scopus-id: 2-s2.0-85126097462
3836
12Growth and phycocyanin production with Galdieria sulphuraria UTEX 2919 using xylose, glucose, and corn stover hydrolysates under heterotrophy and mixotrophyCoautor: Ramirez, Octavio T., Portillo F.V.-L., Sierra-Ibarra, Estefania, Vera-Estrella, Rosario, et al.2022ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTSWoS-id: 000810451000002
Scopus-id: 2-s2.0-85131432834
2633
13Effect of sericin, a silk derived protein, on the amplification of Zika virus in insect and mammalian cell culturesCoautor: Ramirez, Octavio T., Alcala, Ana C., Contreras, Martha A., Cuevas-Juarez, Esmeralda, et al.2022JOURNAL OF BIOTECHNOLOGYWoS-id: 000860321500004
Scopus-id: 2-s2.0-85131401014
33
14Comparable diagnostic accuracy of SARS-CoV-2 Spike RBD and N-specific IgG tests to determine pre-vaccination nation-wide baseline seroprevalence in MexicoCoautor: Ramirez, Octavio T., Martinez-Barnetche, Jesus, Carnalla, Martha, Gaspar-Castillo, Carlos, et al.2022SCIENTIFIC REPORTSWoS-id: 000874705000112
Scopus-id: 2-s2.0-85140809582
1212
15A novel method for the in vitro assembly of virus-like particles and multimeric proteinsCoautor: Ramirez, Octavio T., Rodriguez, Mabel, Castro-Acosta, Ricardo M., Ruiz-Morales, Elias R., et al.2021BIOTECHNOLOGY LETTERSWoS-id: 000622652900001
Scopus-id: 2-s2.0-85101955278
33
16Glycobiotechnology of the Insect Cell-Baculovirus Expression SystemCoautor: Ramirez, Octavio T., Palomares, Laura A., Srivastava, Indresh K., Cox, Manon M. J.2021Advances in Biochemical Engineering-BiotechnologyWoS-id: 000691738200004
Scopus-id: 2-s2.0-85111851217
2728
17Understanding cellular interactions with nanomaterials: towards a rational design of medical nanodevicesCoautor: Ramirez, Octavio T., Villanueva-Flores, Francisca, Castro-Lugo, Andres, Palomares, Laura A.2020NanotechnologyWoS-id: 000520978400001
Scopus-id: 2-s2.0-85080125614
130155
18Dynamic Modeling of CHO Cell Metabolism Using the Hybrid Cybernetic Approach With a Novel Elementary Mode Analysis StrategyCoautor: Ramírez O.T., Martínez J.A., Bulté D.B., Contreras M.A., et al.2020Frontiers in Bioengineering and BiotechnologyWoS-id: 000531245200001
Scopus-id: 2-s2.0-85083964675
1718
19Overexpression of the mitochondrial pyruvate carrier reduces lactate production and increases recombinant protein productivity in CHO cellsCoautor: Ramirez, Octavio T., Bulte, Dubhe B., Palomares, Laura A., Parra, Carolina Gomez, et al.2020BIOTECHNOLOGY AND BIOENGINEERINGWoS-id: 000540461900001
Scopus-id: 2-s2.0-85089414000
1918
20Enrichment of microsomes from Chinese hamster ovary cells by subcellular fractionation for its use in proteomic analysisCoautor: Ramírez O.T., Pérez-Rodriguez S., de Jesús Ramírez-Lira M., Wulff T., et al.2020PLOS ONEWoS-id: 000565553400053
Scopus-id: 2-s2.0-85089924693
55
21Comparison of protein precipitation methods for sample preparation prior to proteomic analysis of Chinese hamster ovary cell homogenates2ᵒ autor: Ramírez O.T., Pérez-Rodriguez S., Trujillo-Roldán M.A., Valdez-Cruz N.A.2020Electronic Journal Of BiotechnologyWoS-id: 000590229400011
Scopus-id: 2-s2.0-85092931284
1516
22Poly(vinyl alcohol co-vinyl acetate) as a novel scaffold for mammalian cell culture and controlled drug releaseCoautor: Ramirez, Octavio T., Villanueva-Flores, Francisca, Miranda-Hernandez, Margarita, Flores-Flores, Jose O., et al.2019JOURNAL OF MATERIALS SCIENCEWoS-id: 000460069500037
Scopus-id: 2-s2.0-85061207632
66
23Rotavirus VP6 protein as a bio-electrochemical scaffold: Molecular dynamics and experimental electrochemistryCoautor: Ramirez O.T., Garcia-Garcia W.I., Vidal-Limon A., Arrocha-Arcos A.A., et al.2019BioelectrochemistryWoS-id: 000464481700021
Scopus-id: 2-s2.0-85062413604
78
24Xylose-glucose co-fermentation to ethanol by Escherichia coli strain MS04 using single- and two-stage continuous cultures under micro-aerated conditionsCoautor: Ramirez, Octavio T., Fernandez-Sandoval, Marco T., Galindez-Mayer, Juvencio, Bolivar, Francisco, et al.2019MICROBIAL CELL FACTORIESWoS-id: 000483042800001
Scopus-id: 2-s2.0-85071431539
2228
25Defining the multiplicity and time of infection for the production of Zaire Ebola virus-like particles in the insect cell-baculovirus expression systemCoautor: Ramírez O.T., Pastor A.R., González-Domínguez G., Díaz-Salinas M.A., et al.2019VaccineWoS-id: 000496858100005
Scopus-id: 2-s2.0-85067914146
910
26Flocculation of CHO cells for primary separation of recombinant glycoproteins: Effect on glycosylation profilesCoautor: Ramirez, Octavio T., Gomez, Itzcoatl A., Hernandez, Vanessa, Palomares, Laura A.2018BIOCHEMICAL ENGINEERING JOURNALWoS-id: 000433266500027
Scopus-id: 2-s2.0-85041477306
56
27Metabolic modeling and response surface analysis of an Escherichia coli strain engineered for shikimic acid productionCoautor: Ramirez, Octavio T., Martinez, Juan A., Rodriguez, Alberto, Moreno, Fabian, et al.2018BMC SYSTEMS BIOLOGYWoS-id: 000450275600001
Scopus-id: 2-s2.0-85056348372
910
28Real-time imaging reveals unique heterogeneous population features in insect cell culturesCoautor: Ramirez, Octavio T., Hidalgo, David, Paz, Enrique, Palomares, Laura A.2017JOURNAL OF BIOTECHNOLOGYWoS-id: 000412035000010
Scopus-id: 2-s2.0-85028315662
45
29Subcellular fractionation of suspension CHO cells producing a monoclonal antibody by a differential and isopicnic centrifugation based protocol.Coautor: Ramirez, O. T., Rodriguez, S. P., Lira, M. R., Cruz, N. V., et al.2017MOLECULAR BIOLOGY OF THE CELLWoS-id: 000426664302078
00
30Physiological effects of pH gradients on Escherichia coli during plasmid DNA productionCoautor: Ramirez, Octavio T., Cortes, Jose T., Flores, Noemi, Bolivar, Francisco, et al.2016BIOTECHNOLOGY AND BIOENGINEERINGWoS-id: 000369015100015
Scopus-id: 2-s2.0-84955749623
2428
31Effect of Temperature Downshift on the Transcriptomic Responses of Chinese Hamster Ovary Cells Using Recombinant Human Tissue Plasminogen Activator Production CultureCoautor: Ramirez, Octavio T., Bedoya-Lopez, Andrea, Estrada, Karel, Sanchez-Flores, Alejandro, et al.2016PLOS ONEWoS-id: 000372582800072
Scopus-id: 2-s2.0-84962144653
5456
32Molecular Docking and Aberration-Corrected STEM of Palladium Nanoparticles on Viral TemplatesCoautor: Ramirez, Octavio T., Carreno-Fuentes, Liliana, Bahena, Daniel, Palomares, Laura A., et al.2016METALSWoS-id: 000385527100007
Scopus-id: 2-s2.0-84984846546
68
33Toward efficient microaerobic processes using engineered Escherichia coli W3110 strainsCoautor: Ramirez, Octavio T., Pablos, Tania E., Olivares, Roberto, Carlos Sigala, Juan, et al.2016ENGINEERING IN LIFE SCIENCESWoS-id: 000386156400002
Scopus-id: 2-s2.0-84963828810
1111
34An Overview of Cell Culture Engineering for the Insect Cell-Baculovirus Expression Vector System (BEVS)Coautor y autor de correspondencia: Ramirez, Octavio T., Palomares, Laura A., Realpe, Mauricio2015Cell EngineeringWoS-id: 000357817100016
150
35Effect of metal catalyzed oxidation in recombinant viral protein assembliesCoautor: Ramirez, OT, Castro-Acosta, RM, Rodriguez-Limas, WA, Valderrama, B, et al.2014MICROBIAL CELL FACTORIESWoS-id: 000333117900001
Scopus-id: 2-s2.0-84894246950
1617
36Understanding internalization of rotavirus VP6 nanotubes by cells: towards a recombinant vaccineCoautor: Ramírez O.T., Rodríguez M., Wood C., Sanchez-López R., et al.2014ARCHIVES OF VIROLOGYWoS-id: 000335777600017
Scopus-id: 2-s2.0-84899974344
1515
37Effect of growth rate on plasmid DNA production and metabolic performance ofengineered Escherichia coli strainsCoautor: Ramírez O.T., Wunderlich M., Taymaz-Nikerel H., Gosset G., et al.2014JOURNAL OF BIOSCIENCE AND BIOENGINEERINGWoS-id: 000335874000015
Scopus-id: 2-s2.0-84893807208
1925
38Immunogenicity and protective efficacy of yeast extracts containing rotavirus-like particles: A potential veterinary vaccineCoautor: Ramírez O.T., Rodríguez-Limas W.A., Pastor A.R., Esquivel-Soto E., et al.2014VaccineWoS-id: 000336704900006
Scopus-id: 2-s2.0-84899967218
813
39The assembly conformation of rotavirus VP6 determines its protective efficacy against rotavirus challenge in miceCoautor: Ramírez O.T., Pastor A.R., Rodríguez-Limas W.A., Contreras M.A., et al.2014VaccineWoS-id: 000336704900019
Scopus-id: 2-s2.0-84899951439
2831
40Characterization of conductive nanobiomaterials derived from viral assemblies by low-voltage STEM imaging and Raman scatteringCoautor: Ramírez O.T., Plascencia-Villa G., Carreno-Fuentes, L, Bahena D., et al.2014NanotechnologyWoS-id: 000342503400010
Scopus-id: 2-s2.0-84918833436
35
41Modulating the physicochemical and structural properties of gold-functionalized protein nanotubes through thiol surface modificationCoautor: Ramírez O.T., Carreno-Fuentes, L, Plascencia-Villa G., Palomares L.A., et al.2014LangmuirWoS-id: 000346685100033
Scopus-id: 2-s2.0-84918823538
712
42Modification of glucose import capacity in Escherichia coli: Physiologic consequences and utility for improving DNA vaccine productionCoautor: Ramírez O.T., Fuentes L.G., Lara A.R., Martínez L.M., et al.2013MICROBIAL CELL FACTORIESWoS-id: 000318981300001
Scopus-id: 2-s2.0-84876862339
4244
43Effect of controlled redox potential and dissolved oxygen on the in vitro refolding of an E. coli alkaline phosphatase and chicken lysozymeCoautor: Ramírez O.T., Meneses-Acosta A., Vizcaíno-Meza L.R., Ayala-Castro H.G., et al.2013ENZYME AND MICROBIAL TECHNOLOGYWoS-id: 000319237600002
Scopus-id: 2-s2.0-84876743450
46
44Strategies for specifically directing metal functionalization of protein nanotubes: Cnstructing protein coated silver nanowiresCoautor: Ramírez O.T., Carreno-Fuentes, L, Ascencio J.A., Medina A., et al.2013NanotechnologyWoS-id: 000319327600015
Scopus-id: 2-s2.0-84878066672
1916
45Structural characterization of rotavirus-directed synthesis and assembly of metallic nanoparticle arraysCoautor: Ramírez O.T., Plascencia-Villa G., Medina A., Palomares L.A., et al.2013JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGYWoS-id: 000320632200051
Scopus-id: 2-s2.0-84878076925
67
46Enhancing thermo-induced recombinant protein production in Escherichia coli by temperature oscillations and post-induction nutrient feeding strategiesCoautor: Ramírez O.T., Caspeta L., Lara A.R., Pérez N.O., et al.2013JOURNAL OF BIOTECHNOLOGYWoS-id: 000323093400007
Scopus-id: 2-s2.0-84880007600
1314
47Production of silver nanowires inside rotavirus VP6 tubesCoautor: Ramirez, OT, Carreno-Fuentes, L, Medina, A, Ascencio, JA, et al.2013Abstracts Of Papers Of The American Chemical SocietyWoS-id: 000323851301153
00
48Constitutive expression of selected genes from the pentose phosphate and aromatic pathways increases the shikimic acid yield in high-glucose batch cultures of an Escherichia coli strain lacking PTS and pykFCoautor: Ramírez O.T., Rodriguez A., Martínez J.A., Báez-Viveros J.L., et al.2013MICROBIAL CELL FACTORIESWoS-id: 000325795900001
Scopus-id: 2-s2.0-84884693506
6573
49Effect of heating rate on pDNA production by E. coliCoautor y autor de correspondencia: Ramírez O.T., Jaén K.E., Lara A.R.2013BIOCHEMICAL ENGINEERING JOURNALWoS-id: 000326421100030
Scopus-id: 2-s2.0-84883813170
1417
50Enhanced production of plasmid DNA by engineered Escherichia coli strainsCoautor: Ramírez O.T., Pablos T.E., Soto R., Mora E.M., et al.2012JOURNAL OF BIOTECHNOLOGYWoS-id: 000302771900008
Scopus-id: 2-s2.0-84859481011
1616
51Plasmid DNA production for therapeutic applications2ᵒ autor y autor de correspondencia: Ramírez O.T., Lara A.R.2012Methods in Molecular BiologyWoS-id: 000303413800014
Scopus-id: 2-s2.0-84855926389
3546
52Simultaneous expression of recombinant proteins in the insect cell-baculovirus system: Production of virus-like particlesCoautor y autor de correspondencia: Ramirez, OT, Palomares, LA, Mena, JA2012MethodsWoS-id: 000303974100008
Scopus-id: 2-s2.0-84860485720
2325
53New insights into Escherichia coli metabolism: carbon scavenging, acetate metabolism and carbon recycling responses during growth on glycerolCoautor: Ramirez, OT, Martinez-Gomez, K, Flores, N, Castaneda, HM, et al.2012MICROBIAL CELL FACTORIESWoS-id: 000306377300001
Scopus-id: 2-s2.0-84862179493
167181
54Control of redox potential in hybridoma cultures: effects on MAb production, metabolism, and apoptosisCoautor y autor de correspondencia: Ramírez O.T., Meneses-Acosta A., Gómez A.2012JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGYWoS-id: 000307248300011
Scopus-id: 2-s2.0-84865175081
44
55Effect of Oxidation on Viral Protein Macrostructures AssembliesCoautor: Ramirez, OT, Castro-Acosta, RM, Valderrama, B, Palomares, LA2012FREE RADICAL BIOLOGY AND MEDICINEWoS-id: 000310660600347
00
56Engineering Escherichia coli to increase plasmid DNA production in high cell-density cultivations in batch modeCoautor: Ramírez O.T., Borja G.M., Mora, EM, Barrón B., et al.2012MICROBIAL CELL FACTORIESWoS-id: 000311451700001
Scopus-id: 2-s2.0-84866297923
5155
57Flocculation of CHO cells for separation of recombinant glycoproteins: Effect on glycosylation profiles1ᵉʳ autor: Ramirez, OT, Gomez, IA2012Abstracts Of Papers Of The American Chemical SocietyWoS-id: 000324475100737
00
58Expression of recombinant proteins by a novel thermoinducible two-compartment continuous production system1ᵉʳ autor: Ramirez, OT, Nino, OL, Tepez, NA2012Abstracts Of Papers Of The American Chemical SocietyWoS-id: 000324475100867
00
59Intracellular Localization of Adeno-Associated Viral Proteins Expressed in Insect Cells2ᵒ autor: Ramirez, OT, Gallo-Ramirez, LE, Palomares, LA2011BIOTECHNOLOGY PROGRESSWoS-id: 000289431600023
Scopus-id: 2-s2.0-79954426212
77
60Strategies for the purification and characterization of protein scaffolds for the production of hybrid nanobiomaterialsCoautor: Ramirez, OT, Plascencia-Villa, G, Mena, JA, Castro-Acosta, RM, et al.2011JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCESWoS-id: 000290645400012
Scopus-id: 2-s2.0-79955007794
2120
61Molecular and process design for rotavirus-like particle production in Saccharomyces cerevisiaeCoautor: Ramírez O.T., Rodríguez-Limas W.A., Tyo, KEJ, Nielsen J., et al.2011MICROBIAL CELL FACTORIESWoS-id: 000291855700002
Scopus-id: 2-s2.0-79955852979
6261
62Simulation of dissolved CO2 gradients in a scale-down system: A metabolic and transcriptional study of recombinant Escherichia coliCoautor: Ramirez, OT, Baez, A, Flores, N, Bolivar, F2011BIOTECHNOLOGY JOURNALWoS-id: 000294108100006
Scopus-id: 2-s2.0-79961182391
2223
63Vitreoscilla hemoglobin expression in engineered Escherichia coli: Improved performance in high cell-density batch cultivationsCoautor: Ramírez O.T., Pablos T.E., Mora E.M., Le Borgne S., et al.2011BIOTECHNOLOGY JOURNALWoS-id: 000294108100009
Scopus-id: 2-s2.0-79961192899
1921
64Comparison of oxygen enriched air vs. pressure cultivations to increase oxygen transfer and to scale-up plasmid DNA production fermentationsCoautor: Ramírez O.T., Lara A.R., Knabben I., Regestein L., et al.2011ENGINEERING IN LIFE SCIENCESWoS-id: 000294263600006
Scopus-id: 2-s2.0-84860389876
2425
65High cell-density cultivation in batch mode for plasmid DNA production by a metabolically engineered E-coli strain with minimized overflow metabolismCoautor: Ramírez O.T., Soto R., Caspeta L., Barrón B., et al.2011BIOCHEMICAL ENGINEERING JOURNALWoS-id: 000295197000009
Scopus-id: 2-s2.0-80051786518
2628
66Molecular responses of Escherichia coli caused by heat stress and recombinant protein production during temperature induction2ᵒ autor: Ramírez O.T., Valdez-Cruz N.A., Trujillo-Roldán M.A.2011Bioengineered BugsScopus-id: 2-s2.0-79952467659
018
67Production of recombinant proteins in E. coli by the heat inducible expression system based on the phage lambda pL and/or pR promotersCoautor: Ramírez O.T., Valdez-Cruz N.A., Caspeta L., Pérez N.O., et al.2010MICROBIAL CELL FACTORIESWoS-id: 000276409100001
Scopus-id: 2-s2.0-77951237154
158173
68Separation and quantification of doubleand triple-layered rotavirus-like particles by CZECoautor: Ramirez, OT, Castro-Acosta, RM, Revilla, AL, Palomares, LA2010ElectrophoresisWoS-id: 000277778900013
Scopus-id: 2-s2.0-77951187440
1819
69Metabolic engineering for the production of shikimic acid in an evolved Escherichia coli strain lacking the phosphoenolpyruvate: carbohydrate phosphotransferase systemCoautor: Ramirez, OT, Escalante, A, Calderon, R, Valdivia, A, et al.2010MICROBIAL CELL FACTORIESWoS-id: 000278309000001
Scopus-id: 2-s2.0-77950649821
8494
70Transcriptional and protease activity analysis as tools for increasing rotavirus protein production in Saccharomyces cerevisiaeCoautor: Ramirez, O, Rodriguez-Limas, W, Tyo, K, Palomares, L, et al.2010FEBS JOURNALWoS-id: 000278565100353
00
71Design and characterization of a one-compartment scale-down system for simulating dissolved oxygen tension gradientsCoautor y autor de correspondencia: Ramírez O.T., De León-Rodríguez A., Galindo E.2010JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGYWoS-id: 000279510900007
Scopus-id: 2-s2.0-77953510736
46
72The Effect of Heating Rate on Escherichia coli Metabolism, Physiological Stress, Transcriptional Response, and Production of Temperature-induced Recombinant Protein: A Scale-DowCoautor: Ramírez O.T., Caspeta L., Flores N., Pérez N.O., et al.2009BIOTECHNOLOGY AND BIOENGINEERINGWoS-id: 000262540300014
Scopus-id: 2-s2.0-58249087221
6972
73Metabolic and Transcriptional Response of Recombinant Escherichia coli to Elevated Dissolved Carbon Dioxide ConcentrationsCoautor: Ramirez, OT, Baez, A, Flores, N, Bolivar, F2009BIOTECHNOLOGY AND BIOENGINEERINGWoS-id: 000269096800011
Scopus-id: 2-s2.0-69249095394
3841
74Impact of Physicochemical Parameters on In Vitro Assembly and Disassembly Kinetics of Recombinant Triple-Layered Rotavirus-Like ParticlesCoautor: Ramírez O.T., Mellado, MCM, Mena J.A., Lopes A., et al.2009BIOTECHNOLOGY AND BIOENGINEERINGWoS-id: 000271173400005
Scopus-id: 2-s2.0-70350492883
2628
75Use of Recombinant Rotavirus VP6 Nanotubes as a Multifunctional Template for the Synthesis of Nanobiomaterials Functionalized With MetalsCoautor: Ramirez, OT, Plascencia-Villa, G, Saniger, JM, Ascencio, JA, et al.2009BIOTECHNOLOGY AND BIOENGINEERINGWoS-id: 000271728400005
Scopus-id: 2-s2.0-70350542837
2832
76Genotypification of bovine group A rotavirus in MexicoCoautor: Ramirez, OT, Rodriguez-Limas, WA, Flores-Samaniego, B, de la Mora, G, et al.2009VaccineWoS-id: 000271922700005
Scopus-id: 2-s2.0-70350138224
1114
77Fast Dynamic Response of the Fermentative Metabolism of Escherichia coli to Aerobic and Anaerobic Glucose PulsesCoautor: Ramírez O.T., Lara A.R., Taymaz-Nikerel H., Mashego M.R., et al.2009BIOTECHNOLOGY AND BIOENGINEERINGWoS-id: 000273813400011
Scopus-id: 2-s2.0-70350503165
5869
78Challenges for the production of virus-like particles in insect cells: The case of rotavirus-like particles2ᵒ autor y autor de correspondencia: Ramirez, OT, Palomares, LA2009BIOCHEMICAL ENGINEERING JOURNALWoS-id: 000274704200001
Scopus-id: 2-s2.0-67349117338
5357
79Utility of an Escherichia coli strain engineered in the substrate uptake system for improved culture performance at high glucose and cell concentrations: An fed-batch culturesCoautor: Ramirez, OT, Lara, AR, Caspeta, L, Gosset, G, et al.2008BIOTECHNOLOGY AND BIOENGINEERINGWoS-id: 000253277300017
Scopus-id: 2-s2.0-39549119605
6667
80Coutilization of glucose and glycerol enhances the production of aromatic compounds in an Escherichia coli strain lacking the phosphoenolpyruvate: Carbohydrate phosphotransferase systemCoautor: Ramirez, OT, Martinez, K, de Anda, R, Hernandez, G, et al.2008MICROBIAL CELL FACTORIESWoS-id: 000253532600001
Scopus-id: 2-s2.0-39749112439
4854
81Metabolic engineering of Escherichia coli for L-tyrosine production by expression of genes coding for the chorismate mutase domain of the native chorismate mutase-prephenate dehCoautor: Ramirez, OT, Chavez-Bejar, MI, Lara, AR, Lopez, H, et al.2008APPLIED AND ENVIRONMENTAL MICROBIOLOGYWoS-id: 000256074900044
Scopus-id: 2-s2.0-44249098772
6169
82Scanning tunneling microscopy of rotavirus VP6 protein self-assembled into nanotubes and nanospheresCoautor: Ramírez O.T., Rodríguez-Galván A., Heredia A., Plascencia-Villa G., et al.2008Journal of Scanning Probe MicroscopyScopus-id: 2-s2.0-67649467343
04
83Differences in the glycosylation profile of a monoclonal antibody produced by hybridomas cultured in serum-supplemented, serum-free or chemically defined mediaCoautor: Ramírez O.T., Serrato J.A., Hernández V., Estrada-Mondaca S., et al.2007BIOTECHNOLOGY AND APPLIED BIOCHEMISTRYWoS-id: 000246946800005
Scopus-id: 2-s2.0-34249889580
3944
84Population kinetics during simultaneous infection of insect cells with two different recombinant baculoviruses for the production of rotavirus-like particles2ᵒ autor: Ramírez O.T., Mena J.A., Palomares L.A.2007BMC BIOTECHNOLOGYWoS-id: 000248184500001
Scopus-id: 2-s2.0-34547115676
3234
85Growth recovery on glucose under aerobic conditions of an Escherichia coli strain carrying a phosphoenolpyruvate:carbohydrate phosphotransferase system deletion by inactivating arcA and overexpressing the genes coding for glucokinase and galCoautor: Ramírez O.T., Flores N., Leal L., Sigala J.C., et al.2007JOURNAL OF MOLECULAR MICROBIOLOGY AND BIOTECHNOLOGYWoS-id: 000248808400012
Scopus-id: 2-s2.0-38449090698
3636
86Transcriptional and metabolic response of recombinant Escherichia coli to spatial dissolved oxygen tension gradients simulated in a scale-down systemCoautor: Ramírez O.T., Lara A.R., Leal L., Flores N., et al.2006BIOTECHNOLOGY AND BIOENGINEERINGWoS-id: 000234773400019
Scopus-id: 2-s2.0-33645580745
8995
87Intracellular distribution of rotavirus structural proteins and virus-like particles expressed in the insect cell-baculovirus system2ᵒ autor: Ramírez O.T., Mena J.A., Palomares L.A.2006JOURNAL OF BIOTECHNOLOGYWoS-id: 000236823800005
Scopus-id: 2-s2.0-33645369679
3736
88Replacement of the glucose phosphotransferase transport system by galactose permease reduces acetate accumulation and improves process performance of Escherichia coli for recombinant protein production without impairment of growth rateCoautor: Ramírez O.T., de Anda R., Lara A.R., Hernández V., et al.2006METABOLIC ENGINEERINGWoS-id: 000237888400009
Scopus-id: 2-s2.0-33646082049
119124
89Engineering Escherichia coli to improve culture performance and reduce formation of by-products during recombinant protein production under transient intermittent anaerobic conditionsCoautor: Ramírez O.T., Lara A.R., Vazquez-Limón C., Gosset G., et al.2006BIOTECHNOLOGY AND BIOENGINEERINGWoS-id: 000239541200017
Scopus-id: 2-s2.0-33747120984
3945
90Rotavirus-like particles primary recovery from insect cells in aqueous two-phase systemsCoautor: Ramírez O.T., Benavides J., Mena J.A., Cisneros-Ruiz M., et al.2006JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCESWoS-id: 000240712700008
Scopus-id: 2-s2.0-33748182784
8284
91Living with heterogeneities in bioreactors: Understanding the effects of environmental gradients on cellsCoautor: Ramírez O.T., Lara A.R., Galindo E., Palomares L.A.2006MOLECULAR BIOTECHNOLOGYWoS-id: 000242502300006
Scopus-id: 2-s2.0-33846885651
331356
92Production of ß-galactosidase by Kluyveromyces marxianus under oscillating dissolved oxygen tensionCoautor: Ramírez O.T., Cortés G., Trujillo-Roldán M.A., Galindo E.2005PROCESS BIOCHEMISTRYWoS-id: 000225235400037
Scopus-id: 2-s2.0-7444242068
3235
93Culture of Escherichia coli under dissolved oxygen gradients simulated in a two-compartment scale-down system: Metabolic response and production of recombinant proteinCoautor: Ramírez O.T., Sandoval-Basurto E.A., Gosset G., Bolivar F.2005BIOTECHNOLOGY AND BIOENGINEERINGWoS-id: 000226701100010
Scopus-id: 2-s2.0-14244251570
6879
94Cell Culture Engineering IX1ᵉʳ autor: Ramírez O.T., Piret J., Krummen L., Konstantinov K.2005BIOTECHNOLOGY PROGRESSWoS-id: 000226934800001
Scopus-id: 2-s2.0-84888890052
00
95Effect of production method and gene amplification on the glycosylation pattern of a secreted reporter protein in CHO cellsCoautor: Ramírez O.T., Lipscomb M.L., Palomares L.A., Hernández V., et al.2005BIOTECHNOLOGY PROGRESSWoS-id: 000226934800007
Scopus-id: 2-s2.0-13544270916
3441
96Mannosamine supplementation extends the N-acetylglucosaminylation of recombinant human secreted alkaline phosphatase produced in Trichoplusia ni (cabbage looper) insect cell culturesCoautor y autor de correspondencia: Ramírez O.T., Estrada-Mondaca S., Delgado-Bustos L.A.2005BIOTECHNOLOGY AND APPLIED BIOCHEMISTRYWoS-id: 000231192900004
Scopus-id: 2-s2.0-23644436651
78
97Quantification of rotavirus-like particles by gel permeation chromatography2ᵒ autor: Ramírez O.T., Mena J.A., Palomares L.A.2005JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCESWoS-id: 000231768900034
Scopus-id: 2-s2.0-24044548021
2630
98Specific growth rate determines the molecular mass of the alginate produced by Azotobacter vinelandiiCoautor: Ramírez O.T., Priego-Jimenéz R., Peña C., Galindo E.2005BIOCHEMICAL ENGINEERING JOURNALWoS-id: 000231935800001
Scopus-id: 2-s2.0-23944459546
2731
99Role of pyruvate oxidase in Escherichia coli strains lacking the phosphoenolpyruvate:carbohydrate phosphotransferase systemCoautor: Ramírez O.T., Flores N., De Anda R., Flores S., et al.2005JOURNAL OF MOLECULAR MICROBIOLOGY AND BIOTECHNOLOGYWoS-id: 000232082700003
Scopus-id: 2-s2.0-25444522888
2424
100Utilization of oxygen uptake rate to assess the role of glucose and glutamine in the metabolism of infected insect cell culturesCoautor y autor de correspondencia: Ramírez O.T., Palomares L.A., López S.2004BIOCHEMICAL ENGINEERING JOURNALWoS-id: 000221565300013
Scopus-id: 2-s2.0-2342552941
4644
101Heterogeneous conditions in dissolved oxygen affect N-glycosylation but not productivity of a monoclonal antibody in hybridoma culturesCoautor: Ramírez O.T., Serrato J.A., Palomares L.A., Meneses-Acosta A.2004BIOTECHNOLOGY AND BIOENGINEERINGWoS-id: 000224266600005
Scopus-id: 2-s2.0-7044232898
6066
102Production of recombinant proteins: challenges and solutions.Coautor y autor de correspondencia: Ramírez O.T., Palomares L.A., Estrada-Mondaca S.2004Methods in Molecular BiologyScopus-id: 2-s2.0-4644299621
0146
103Titration of non-occluded baculovirus using a cell viability assay2ᵒ autor: Ramírez O.T., Mena J.A., Palomares L.A.2003BiotechniquesWoS-id: 000180892500005
Scopus-id: 2-s2.0-0037311940
7576
104Effects of dissolved oxygen tension on the production of recombinant penicillin acylase in Escherichia coliCoautor: Ramírez O.T., De León A., Hernández V., Galindo E.2003ENZYME AND MICROBIAL TECHNOLOGYWoS-id: 000185366500020
Scopus-id: 2-s2.0-0042882411
2432
105Strategies for manipulating the relative concentration of recombinant rotavirus structural proteins during simultaneous production by insect cellsCoautor y autor de correspondencia: Ramírez O.T., Palomares L.A., López S.2002BIOTECHNOLOGY AND BIOENGINEERINGScopus-id: 2-s2.0-0037142388
3239
106Comparative characterization of cell death between Sf9 insect cells and hybridoma culturesCoautor: Ramírez O.T., Meneses-Acosta A., Mendona R.Z., Merchant H., et al.2001BIOTECHNOLOGY AND BIOENGINEERINGWoS-id: 000166774900007
Scopus-id: 2-s2.0-0035916380
2530
107Parameters that determine virus adsorption kinetics: Toward the design of better infection strategies for the insect cell - Baculovirus expression systemCoautor: Ramírez O.T., Petricevich V.L., Palomares L.A., González M.2001ENZYME AND MICROBIAL TECHNOLOGYWoS-id: 000169619400007
Scopus-id: 2-s2.0-0035811945
2325
108Two useful dimensionless parameters that combine physiological, operational and bioreactor design parameters for improved control of dissolved oxygenCoautor: Ramírez O.T., De León A., Barba-De La Rosa A.P., Mayani H., et al.2001BIOTECHNOLOGY LETTERSWoS-id: 000169863100008
Scopus-id: 2-s2.0-0034910147
1216
109Effect of oscillating dissolved oxygen tension on the production of alginate by Azotobacter vinelandiiCoautor: Ramirez O.T., Trujillo-Roldán M.A., Peña C., Galindo E.2001BIOTECHNOLOGY PROGRESSWoS-id: 000172758800009
Scopus-id: 2-s2.0-0035543347
5057
110Erratum: Two useful dimensionless parameters that combine physiological, operational and bioreactor design parameters for improved control of dissolved oxygen (Biotechnology Letters (2001) 23 (1051-1056))Coautor: Ramírez O.T., De León A., Barba-de la Rosa A.P., Mayani H., et al.2001BIOTECHNOLOGY LETTERSScopus-id: 2-s2.0-0034805952
00
111Cell size as a tool to predict the production of recombinant protein by the insect-cell baculovirus expression systemCoautor y autor de correspondencia: Ramírez O.T., Palomares L.A., Pedroza J.C.2001BIOTECHNOLOGY LETTERSScopus-id: 2-s2.0-0035119844
3138
112Evidence of Pluronic F-68 direct interaction with insect cells: Impact on shear protection, recombinant protein, and baculovirus productionCoautor y autor de correspondencia: Ramírez O.T., Palomares L.A., González M.2000ENZYME AND MICROBIAL TECHNOLOGYScopus-id: 2-s2.0-0342632836
5166
113An insight into insect cell metabolism through selective nutrient manipulationCoautor y autor de correspondencia: Ramírez O.T., Mendonça R.Z., Palomares L.A.1999JOURNAL OF BIOTECHNOLOGYWoS-id: 000081199300006
Scopus-id: 2-s2.0-0033010963
3638
114Pharmaceutical biotechnology emerges in Mexico1ᵉʳ autor: Ramirez O.T., Quintero R.1999Nature BiotechnologyScopus-id: 2-s2.0-0032829543
11
115Kinetics of hematopoiesis in Dexter-type long-term cultures established from human umbilical cord blood cellsCoautor: Ramírez O.T., Mayani H., Gutiérrez-Rodríguez M., Espinoza L., et al.1998Stem CellsWoS-id: 000072793200007
Scopus-id: 2-s2.0-15644362188
4248
116Effect of growth rate on the production of ß-galactosidase from Escherichia coli in Bacillus subtilis using glucose-limited exponentially fedbatch cultures2ᵒ autor: Ramírez O.T., Martínez A., Valle F.1998ENZYME AND MICROBIAL TECHNOLOGYWoS-id: 000073262800013
Scopus-id: 2-s2.0-17444446388
2024
117Design, characterization and application of a minibioreactor for the culture of human hematopoietic cells under controlled conditionsCoautor y autor de correspondencia: Ramírez O.T., De León A., Mayani H.1998CytotechnologyWoS-id: 000079991700014
Scopus-id: 2-s2.0-0032438795
3432
118Cell suspension culture of Solanum chrysotrichum (Schldl.) - A plant producing an antifungal spirostanol saponinCoautor: Ramírez O.T., Villarreal Ma.L., Arias C., Feria-Velasco A., et al.1997PLANT CELL TISSUE AND ORGAN CULTUREWoS-id: A1997YH32900007
Scopus-id: 2-s2.0-0030693117
815
119Large-scale cultivation of Solanum chrysotrichum cells: Production of the antifungal saponin SC-1 in 100-l airlift bioreactorsCoautor: Ramírez O.T., Villarreal Ma.L., Arias C., Vega J., et al.1997PLANT CELL REPORTSScopus-id: 2-s2.0-0030947489
010
120Improvement of culture conditions to overproduce ß-galactosidase from Escherichia coli in Bacillus subtilis2ᵒ autor: Ramírez O.T., Martínez A., Valle F.1997APPLIED MICROBIOLOGY AND BIOTECHNOLOGYWoS-id: A1997WF46400006
Scopus-id: 2-s2.0-0031039821
2224
121The use of culture redox potential and oxygen uptake rate for assessing glucose and glutamine depletion in hybridoma culturesCoautor y autor de correspondencia: Ramírez O.T., Higareda A.E., Possani L.D.1997BIOTECHNOLOGY AND BIOENGINEERINGScopus-id: 2-s2.0-0031555504
027
122The effect of dissolved oxygen tension and the utility of oxygen uptake rate in insect cell culture2ᵒ autor y autor de correspondencia: Ramírez O.T., Palomares L.A.1996CytotechnologyWoS-id: A1996WG51200026
Scopus-id: 2-s2.0-0030426430
7073
123A postfermentative stage improves penicillin acylase production by a recombinant E. ColiCoautor y autor de correspondencia: Ramírez O.T., De León A., Galindo E.1996BIOTECHNOLOGY LETTERSScopus-id: 2-s2.0-0029774046
012
124Effect of pH in the synthesis of ampicillin by penicillin acylaseCoautor: Ramírez O.T., Ospina S., Barzana E., López-Munguía A.1996ENZYME AND MICROBIAL TECHNOLOGYWoS-id: A1996VL25700008
Scopus-id: 2-s2.0-0030298227
7987
125Strategies in the design of an enzymatic process for the synthesis of ampicillin: A whole cell E. coli recombinant penicillin amidase biocatalystCoautor: Ramírez O.T., Ospina S., Barzana E., López-Munguía A.1996Progress In BiotechnologyScopus-id: 2-s2.0-27944464296
03
126Recombinant whole cell penicillin acylase biocatalyst: Production, characterization and use in the synthesis and hydrolysis of antibioticsCoautor: Ramirez O.T., Ospina S., Merino E., López-Munguía A.1995BIOTECHNOLOGY LETTERSWoS-id: A1995RH40400012
Scopus-id: 2-s2.0-0029004520
78
127Kinetic study of penicillin acylase production by recombinant E. coli in batch cultures1ᵉʳ autor: Ramírez O.T., Zamora R., Espinosa G., Merino E., et al.1994PROCESS BIOCHEMISTRYWoS-id: A1994MV95200004
Scopus-id: 2-s2.0-0027951891
4855
128Exponentially fed-batch cultures as an alternative to chemostats: The case of penicillin acylase production by recombinant E. coli1ᵉʳ autor: Ramírez O.T., Zamora R., Quintero R., López-Munguía A.1994ENZYME AND MICROBIAL TECHNOLOGYWoS-id: A1994PG56400011
Scopus-id: 2-s2.0-0028518967
2627
129Metabolic and kinetic studies of hybridomas in exponentially fed-batch cultures using T-flasksCoautor y autor de correspondencia: Ramírez O.T., Higareda A.E., Possani L.D.1994CytotechnologyWoS-id: A1994QC63400009
Scopus-id: 2-s2.0-0028708645
67
130Effect of Serum on the Plasma Membrane Fluidity of Hybridomas: An Insight into Its Shear Protective Mechanism1ᵉʳ autor: Ramirez O.T., Mutharasan R.1992BIOTECHNOLOGY PROGRESSWoS-id: A1992HC77500007
Scopus-id: 2-s2.0-0026609774
2931
131Bovine colostrum or milk as a serum substitute for the cultivation of a mouse hybridoma1ᵉʳ autor: Ramírez O.T., Sureshkumar G.K., Mutharasan R.1990BIOTECHNOLOGY AND BIOENGINEERINGWoS-id: A1990CY24100004
Scopus-id: 2-s2.0-0025407793
3531
132Cell cycle- and growth phase-dependent variations in size distribution, antibody productivity, and oxygen demand in hybridoma cultures1ᵉʳ autor: Ramirez O.T., Mutharasan R.1990BIOTECHNOLOGY AND BIOENGINEERINGWoS-id: A1990EE14000013
Scopus-id: 2-s2.0-0025499794
123129
133The role of the plasma membrane fluidity on the shear sensitivity of hybridomas grown under hydrodynamic stress1ᵉʳ autor: Ramírez O.T., Mutharasan R.1990BIOTECHNOLOGY AND BIOENGINEERINGWoS-id: A1990ED68600005
Scopus-id: 2-s2.0-0025513915
102109
134Physical immobilization characteristics of a hybridoma in a glass bead packed-bed reactor1ᵉʳ autor: Ramírez O.T., Mutharasan R.1989BIOTECHNOLOGY AND BIOENGINEERINGWoS-id: A1989T464100015
Scopus-id: 2-s2.0-0024639479
1519
135A novel immobilized hybridoma reactor for the production of monoclonal antibodies1ᵉʳ autor: Ramirez O.T., Mutharasan R., Magee W.E.1987BIOTECHNOL TECHScopus-id: 2-s2.0-34250107267
02
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Documentos no indexados (Humanindex)

# Título del documento ISSN Revista Año Fuente
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Capítulos de libros (WoS y Scopus)

# Título del capítulo Título del libro Autores Alcance Año ISBN Fuente
1Hydrodynamic stress and heterogeneities in animal cell cultureComprehensive BiotechnologyPalomares L.A., Ramírez O.T., Capítulo de un Libro20199780444640475Scopus-id: 2-s2.0-85079513418
2Scale-down: Simulating large-scale cultures in the laboratoryScale-Down: Simulating Large-Scale Cultures In The LaboratoryPalomares, L.A., Ramírez, O.T., Lara, A.R., Capítulo de un Libro20169783527807833Scopus-id: 2-s2.0-85014852348
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Obras con ISBN (Indautor)

# Título del documento Autores Alcance Año ISBN Fuente
1For The Responsible Use Of Genetically Modified OrganismsBolívar-Zapata, Francisco Gonzalo, Carlos Federico Arias-Ortiz, Elena Arriaga Arellano, et al.Libro Completo20129786079516642INDAUTORCIC
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Proyectos

# Nombre Participantes Convocatoria Fecha Inicio Fecha Fin
1Bioingeniería del cultivo de células de eucariotes superiores. Ingeniería de bioprocesos para la producción de proteínas recombinantes de uso terapéutico.OCTAVIO TONATIUH RAMIREZ REIVICH,
Presupuesto de la UNAM asignado a la Dependencia01-01-201430-06-2021
2Desarrollo de nuevas plataformas nanoestructuradas para la regeneración del tejido neuronalOCTAVIO TONATIUH RAMIREZ REIVICH,
Recursos PAPIIT01-01-201629-03-2018
3Laboratorio nacional para la producción y análisis de moléculas y medicamentos biotecnológicos (consolidación)OCTAVIO TONATIUH RAMIREZ REIVICH,
Recursos CONACYT06-04-201705-04-2018
4Laboratorio Nacional para la Producción y Análisis de Moléculas y Medicamentos Biotecnológicos (LAMMB)OCTAVIO TONATIUH RAMIREZ REIVICH,
Recursos CONACYT03-05-201803-05-2019
5Montaje e implementación de un método para la detección y cuantificación de anticuerpos que reconocen a SARS-Cov-2: Siguiendo a COVID-19OCTAVIO TONATIUH RAMIREZ REIVICH,
Sector Pblico (Federal, Estatal o Municipal)05-06-202031-12-2020
6Evaluación de la función efectora y el efecto de amplificación de la infección de anticuerpos contra virus Zika, dengue y SARS-CoV.2OCTAVIO TONATIUH RAMIREZ REIVICH,
Recursos PAPIIT01-01-202131-12-2023
7Equipamiento del Laboratorio Nacional para la Producción y Análisis de Moléculas y Medicamentos Biotecnológicos para determinar la inmunidad celular y humoral durante pruebas clínica relacionadas con COVID-19 y otras enfermedades emergentes.OCTAVIO TONATIUH RAMIREZ REIVICH,
Recursos CONACYT10-09-202131-12-2021
8Caracterización de la heterogeneidad poblacional como base para seleccionar células de ovario de hámster chino con actividad mitocondrial y capacidad biosintética incrementadasOCTAVIO TONATIUH RAMIREZ REIVICH,
Recursos PAPIIT01-01-202431-12-2026
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Participación en Comités de Tesis

# Título del documento Tipo de Tesis Sinodales Autores Año Entidad Url
1Estudio transcripcional de las vías de N-glicosilación en células de ovario de hámster chino (CHO) cultivadas en condiciones de hipotermia moderadaTesis de MaestríaOCTAVIO TONATIUH RAMIREZ REIVICH; Hidalgo Morales, Martha Rosa; 2010Instituto de Biotecnología,
2Caracterizacion de las poblaciones celulares y del metabolismo en cultivos estaticos de celulas hematopoyeticas de sangre de cordon umbilical humanoTesis de MaestríaOCTAVIO TONATIUH RAMIREZ REIVICH; Valderrama Bonilla, Alexandra; 2001
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Docencia Impartida

# Entidad Nivel Asignatura Año Semestre Alumnos
1Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACIÓN I20242024-21
2Instituto de BiotecnologíaMaestríaCURSO III DINÁMICA Y CONTROL DE BIORREACTORES20242024-21
3Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACIÓN II20242024-21
4Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACIÓN II20242024-21
5Instituto de BiotecnologíaMaestríaCURSO IV DINÁMICA Y CONTROL DE BIORREACTORES20242024-21
6Instituto de BiotecnologíaMaestríaSEMINARIO DE INVESTIGACIÓN II20242024-22
7Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACIÓN III20232024-11
8Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACIÓN I20232024-12
9Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACIÓN II20232023-21
10Instituto de BiotecnologíaMaestríaSEMINARIO DE INVESTIGACIÓN III20222022-21
11Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACIÓN III20222022-21
12Instituto de BiotecnologíaMaestríaCURSO IV20222022-21
13Instituto de BiotecnologíaMaestríaCURSO III20222022-20
14Instituto de BiotecnologíaMaestríaSEMINARIO DE INVESTIGACIÓN III20212022-12
15Instituto de BiotecnologíaMaestríaSEMINARIO DE INVESTIGACIÓN II20212022-11
16Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACIÓN II20212022-11
17Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACIÓN III20212022-11
18Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACIÓN III20212022-11
19Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACIÓN III20212021-21
20Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACIÓN II20212021-21
21Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACIÓN II20212021-21
22Instituto de BiotecnologíaMaestríaSEMINARIO DE INVESTIGACIÓN III20212021-21
23Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACIÓN I20212021-21
24Instituto de BiotecnologíaMaestríaSEMINARIO DE INVESTIGACIÓN II20212021-22
25Instituto de BiotecnologíaMaestríaSEMINARIO DE INVESTIGACIÓN II20202021-11
26Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACIÓN I20202021-12
27Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACIÓN II20202021-11
28Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACIÓN I20202020-21
29Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACIÓN II20192020-11
30Instituto de BiotecnologíaMaestríaSEMINARIO DE INVESTIGACIÓN III20192019-22
31Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACIÓN III20192019-21
32Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACIÓN III20192019-21
33Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACIÓN III20192019-21
34Instituto de BiotecnologíaMaestríaSEMINARIO DE INVESTIGACIÓN II20182019-12
35Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACIÓN II20182019-11
36Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACIÓN II20182019-11
37Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACION I20182018-22
38Instituto de BiotecnologíaMaestríaSEMINARIO DE INVESTIGACION III20172018-11
39Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACION III20172018-11
40Facultad de QuímicaMaestríaTRABAJO DE INVESTIGACIÓN II20172017-21
41Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACIÓN I20172017-21
42Instituto de BiotecnologíaMaestríaSEMINARIO DE INVESTIGACIÓN II20172017-21
43Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACIÓN II20172017-21
44Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACION I20162017-11
45Instituto de BiotecnologíaMaestríaSEMINARIO DE INVESTIGACION III20162016-21
46Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACION III20162016-21
47Instituto de BiotecnologíaMaestríaSEMINARIO DE INVESTIGACION II20152016-11
48Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACION II20152016-11
49Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACION I20152015-21
50Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACION III20152015-21
51Instituto de BiotecnologíaMaestríaSEMINARIO DE INVESTIGACION III20152015-21
52Instituto de BiotecnologíaMaestríaSEMINARIO DE INVESTIGACION III20142015-11
53Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACION III20142015-11
54Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACION II20142015-11
55Instituto de BiotecnologíaMaestríaSEMINARIO DE INVESTIGACION II20142015-11
56Instituto de BiotecnologíaMaestríaSEMINARIO DE INVESTIGACION II20142014-21
57Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACION II20142014-21
58Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACION I20132014-11
59Instituto de BiotecnologíaMaestríaSEMINARIO DE INVESTIGACION III20132013-22
60Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACION III20132013-21
61Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACION III20132013-21
62Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACION I20132013-21
63Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACION III20122013-11
64Instituto de BiotecnologíaMaestríaSEMINARIO DE INVESTIGACION III20122013-11
65Instituto de BiotecnologíaMaestríaSEMINARIO DE INVESTIGACION II20122013-12
66Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACION II20122013-11
67Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACION II20122013-11
68Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACION II20122012-21
69Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACION I20122012-22
70Instituto de BiotecnologíaMaestríaSEMINARIO DE INVESTIGACION II20122012-21
71Facultad de QuímicaMaestríaTRABAJO DE INVESTIGACION20122012-21
72Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACION III20122012-21
73Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACION II20112012-11
74Facultad de QuímicaMaestríaTRABAJO DE INVESTIGACION20112012-11
75Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACION I20112012-11
76Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACION III20112011-21
77Instituto de BiotecnologíaMaestríaSEMINARIO DE INVESTIGACION III20112011-21
78Instituto de BiotecnologíaMaestríaSEMINARIO DE INVESTIGACION II20102011-11
79Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACION II20102011-11
80Instituto de BiotecnologíaMaestríaSEMINARIO DE INVESTIGACION III20102011-11
81Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACION III20102011-11
82Instituto de BiotecnologíaMaestríaSEMINARIO DE INVESTIGACION III20102010-21
83Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACION III20102010-21
84Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACION II20102010-21
85Instituto de BiotecnologíaMaestríaSEMINARIO DE INVESTIGACION II20102010-21
86Instituto de BiotecnologíaMaestríaSEMINARIO DE INVESTIGACION I20102010-21
87Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACION I20102010-21
88Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACION I20092010-11
89Instituto de BiotecnologíaMaestríaSEMINARIO DE INVESTIGACION I20092010-11
90Instituto de BiotecnologíaMaestríaSEMINARIO DE INVESTIGACION II20092010-11
91Facultad de QuímicaMaestríaTRABAJO DE INVESTIGACION III20092010-11
92Instituto de BiotecnologíaMaestríaSEMINARIO DE INVESTIGACION III20092010-11
93Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACION III20092010-11
94Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACION II20092010-11
95Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACION II20092009-21
96Instituto de BiotecnologíaMaestríaSEMINARIO DE INVESTIGACION II20092009-21
97Instituto de BiotecnologíaMaestríaSEMINARIO DE INVESTIGACION I20092009-21
98Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACION I20092009-21
99Instituto de BiotecnologíaMaestríaSEMINARIO DE INVESTIGACION I20082009-11
100Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACION I20082009-11
101Instituto de BiotecnologíaMaestríaSEMINARIO DE INVESTIGACION II20082008-21
102Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACION I20082008-21
103Instituto de BiotecnologíaMaestríaSEMINARIO DE INVESTIGACION I20082008-21
104Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACION II20082008-21
105Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACION III20082008-21
106Instituto de BiotecnologíaMaestríaSEMINARIO DE INVESTIGACION III20072008-11
107Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACION II20072008-11
108Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACION III20072008-11
109Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACION III20072008-11
110Instituto de BiotecnologíaMaestríaSEMINARIO DE INVESTIGACION I20072008-11
111Instituto de BiotecnologíaMaestríaTRABAJO DE INVESTIGACION I20072008-11
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Patentes Otorgadas

# Título Inventores Año Sección
1METODO ANALITICO PARA LA CUANTIFICACION DIFERENCIADA DE ESTRUCTURAS VIRALES PROTEICAS MULTIMERICAS.OCTAVIO TONATIUH RAMIREZ REIVICH, ALMA LUISA REVILLA VAZQUEZ, LAURA ALICIA PALOMARES AGUILERA, 2015CHEMISTRY; METALLURGYPERFORMING OPERATIONS; TRANSPORTING
2ESTRATEGIA PARA GENERAR CELULAS INSENSIBLES A CONDICIONES HETEROGENEAS EN BIORREACTORES INDUSTRIALES A TRAVES DE MUTACIONES DE VIAS METABOLICAS ANAEROBIAS.FRANCISCO GONZALO BOLIVAR ZAPATA, GUILLERMO GOSSET LAGARDA, OCTAVIO TONATIUH RAMIREZ REIVICH, et al.2014CHEMISTRY; METALLURGY
3CEPA DE ESCHERICHIA COLI CON MUTACIONES PARA LA ALTA PRODUCCION DE ACIDOS NUCLEICOS RECOMBINANTES CON UNA BAJA ACUMULACION DE ACETATO Y SU USO EN CULTIVOS DE ALTA DENSIDAD CELULAR EN MODO LOTE.GUILLERMO GOSSET LAGARDA, OCTAVIO TONATIUH RAMIREZ REIVICH, 2016CHEMISTRY; METALLURGY
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No se encuentran registros en la base de datos de libros completos (Humanindex).

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Capítulos de libros (Humanindex)

# Título del libro Título del capítulo ISBN Editorial Año Fuente